Results 1 to 10 of about 78,834 (283)

Widespread macrolide resistance among rapidly growing mycobacteria due to plasmids containing erm(55) [PDF]

Scientific Reports
Macrolides (clarithromycin and azithromycin) are a mainstay of therapy for infections caused by rapidly growing mycobacteria (RGM). Historically, macrolide resistance in RGM species is associated with mutations in the 23S rRNA gene and chromosomal ...
Christopher I. Graham, Barbara A. Brown-Elliott, Bibiana Gonzalez-Ramirez, Kavya Somayaji, Stephanie Melton, Michelle Wuzinski, Nancy L. Wengenack, Richard J. Wallace, David C. Alexander   +8 more
doaj   +2 more sources

Biology of clinical mycobacteria strains

Біологічні студії, 2009
Mycobacteria are very varied microorganisms. This peculiarity make great trouble among ftysiatres, because quantity of patients increases and clinical essence of diseases, which caused by mycobacteria, often are not understand.
H. Yavorska, R. Sybirna
doaj   +3 more sources

Different PPD-stimulated cytokine responses from patients infected with genetically distinct Mycobacterium tuberculosis complex lineages

International Journal of Infectious Diseases, 2021
Objectives: The genetic diversity of Mycobacterium tuberculosis complex (MTBC) influences the immune response of the host, which may affect the immunodiagnostic tests and biomarker assessment studies used for tuberculosis (TB).
Paulo Ranaivomanana, Marie Sylvianne Rabodoarivelo, Mame Diarra Bousso Ndiaye, Niaina Rakotosamimanana, Voahangy Rasolofo   +4 more
doaj   +1 more source

From 3D to 2D: Harmonization of Protocols for Two-dimensional Cultures on Cell Culture Inserts of Intestinal Organoids from Various Species

Bio-Protocol, 2022
In the expanding field of intestinal organoid research, various protocols for three- and two-dimensional organoid-derived cell cultures exist. Two-dimensional organoid-derived monolayers are used to overcome some limitations of three-dimensional organoid
David Warschkau, Estefania Delgado-Betancourt, David Holthaus, Antonia Müller, Gudrun Kliem, Susanne Krug, Joerg- Schulzke, Toni Aebischer, Christian Klotz, Frank Seeber   +9 more
doaj   +1 more source

Evolution and spread of a highly drug resistant strain of Mycobacterium tuberculosis in Papua New Guinea

BMC Infectious Diseases, 2022
Background Molecular mechanisms determining the transmission and prevalence of drug resistant tuberculosis (DR-TB) in Papua New Guinea (PNG) are poorly understood. We used genomic and drug susceptibility data to explore the evolutionary history, temporal
Arnold Bainomugisa, Evelyn Lavu, Sushil Pandey, Suman Majumdar, Jennifer Banamu, Chris Coulter, Ben Marais, Lachlan Coin, Stephen M. Graham, Philipp du Cros   +9 more
doaj   +1 more source

Mycobacteria

Microbiology Spectrum, 2016
ABSTRACT The immunocompromised host is at increased risk of Mycobacterium tuberculosis complex and nontuberculous mycobacteria infection. Although Mycobacterium tuberculosis complex is a significant mycobacterial pathogen, nontuberculous mycobacteria causes substantial disease in ...
Patricia J, Simner, Gail L, Woods, Nancy L, Wengenack   +2 more
openaire   +3 more sources

Phenotypic Diversity of Cryptococcus neoformans var. neoformans Clinical Isolates from Localized and Disseminated Infections

Microorganisms, 2022
Cryptococcus neoformans var. neoformans is the second most prevalent agent of cryptococcosis in central Europe. Infections mostly present with localized skin and disseminated infections.
Zena M. Birkenfeld, Nikita Dittel, Thomas Harrer, Christoph Stephan, Albrecht F. Kiderlen, Volker Rickerts   +5 more
doaj   +1 more source

Urine lipoarabinomannan in HIV uninfected, smear negative, symptomatic TB patients: effective sample pretreatment for a sensitive immunoassay and mass spectrometry

Scientific Reports, 2021
Our study sought to determine whether urine lipoarabinomannan (LAM) could be validated in a sample cohort that consisted mainly of HIV uninfected individuals that presented with tuberculosis symptoms.
Anita G. Amin, Prithwiraj De, Barbara Graham, Roger I. Calderon, Molly F. Franke, Delphi Chatterjee   +5 more
doaj   +1 more source

Unique Features of Mycobacterium abscessus Biofilms Formed in Synthetic Cystic Fibrosis Medium

Frontiers in Microbiology, 2021
Characterizing Mycobacterium abscessus complex (MABSC) biofilms under host-relevant conditions is essential to the design of informed therapeutic strategies targeted to this persistent, drug-tolerant, population of extracellular bacilli.
Juan M. Belardinelli, Wei Li, Charlotte Avanzi, Shiva K. Angala, Elena Lian, Crystal J. Wiersma, Zuzana Palčeková, Kevin H. Martin, Bhanupriya Angala, Vinicius C. N. de Moura, Callan Kerns, Victoria Jones, Mercedes Gonzalez-Juarrero, Rebecca M. Davidson, Jerry A. Nick, Jerry A. Nick, Bradley R. Borlee, Mary Jackson   +17 more
doaj   +1 more source

Import and transmission of Mycobacterium orygis and Mycobacterium africanum, Norway

BMC Infectious Diseases, 2021
Background The aim of the current study was to improve our understanding of the origins and transmission of Mycobacterium africanum (MAF) in Norway. Methods Whole-genome sequences (WGS) were generated for all (n = 29) available clinical isolates received
Vegard Eldholm, Janne O. Rønning, Anne Torunn Mengshoel, Trude Arnesen   +3 more
doaj   +1 more source