Results 31 to 40 of about 94,343 (260)

Distribution of environmental mycobacteria in Karonga District, northern Malawi. [PDF]

, 2006
The genus Mycobacterium includes many species that are commonly found in the environment (in soil and water or associated with plants and animals), as well as species that are responsible for two major human diseases, tuberculosis (Mycobacterium ...
Fine, Paul EM, Hirsch, P. R., Floyd, Sian, Chilima, Benson Z, Chilima, B. Z., Clark, Ian M, Hirsch, Penny R, Floyd, S., Clark, I. M., Fine, P. E. M., Clark, Ian, Hirsch, Penny   +11 more
core   +1 more source

Complexities and benefits of adopting next-generation sequencing-based tuberculosis diagnostics: a qualitative study among stakeholders in low and high-income countries

BMJ Open, 2023
Objectives To clarify perceived benefits, barriers and facilitators of Mycobacterium tuberculosis next-generation sequencing implementation in Madagascar and Canada, towards informing implementation of this diagnostic technology in public health agencies
Elysée Nouvet, Niaina Rakotosamimanana, Simon Grandjean Lapierre, Catherine-Audrey Boutin, Maxwell J Smith, Marie-Sylvianne Rabodoarivelo, Omar Mahboob   +6 more
doaj   +1 more source

Late Embryogenesis Abundant Proteins Contribute to the Resistance of Toxoplasma gondii Oocysts against Environmental Stresses

mBio, 2023
Toxoplasma gondii oocysts, which are shed in large quantities in the feces from infected felines, are very stable in the environment, resistant to most inactivation procedures, and highly infectious. The oocyst wall provides an important physical barrier
David Arranz-Solís, David Warschkau, Benedikt T. Fabian, Frank Seeber, Jeroen P. J. Saeij   +4 more
doaj   +1 more source

Longitudinal Variations of M. tuberculosis-Induced IFN-γ Responses in HIV-Negative Pregnant Women Exposed to Tuberculosis

Frontiers in Immunology, 2021
IntroductionPregnancy triggers an alteration of the immune functions and increases the risk of developing the active tuberculosis (TB) symptoms in exposed women. The effect of pregnancy on the Mycobacterium tuberculosis-specific immune responses used for
Paulo Ranaivomanana, Rila Ratovoson, Crisca Razafimahatratra, Arimanitra Razafimahefa, Jonathan Hoffmann, Perlinot Herindrainy, Julio Rakotonirina, Niaina Rakotosamimanana   +7 more
doaj   +1 more source

Nontuberculous mycobacteria isolated from specimens of pulmonary tuberculosis suspects, Northern Tunisia: 2002–2016

BMC Infectious Diseases, 2019
Background Reports on the worldwide ascending trend of pulmonary nontuberculous mycobacteria (NTM) isolation rates and their effective role in respiratory tract infections are compelling.
Reem Gharbi, Besma Mhenni, Saloua Ben Fraj, Helmi Mardassi   +3 more
doaj   +1 more source

Usefulness of Xpert MTB/RIF Ultra for rapid diagnosis of extrapulmonary tuberculosis in Tunisia

Scientific Reports
Extrapulmonary tuberculosis (EPTB) remains a challenging diagnosis. The purpose of this study was to assess the accuracy of Xpert MTB/RIF Ultra (Cepheid, USA) for rapid diagnosis of EPTB in Tunisia.
Imen Bouzouita, Asma Ghariani, Khouloud Ben Dhaou, Sabrine Jemaeil, Leila Essaalah, Sana Bejaoui, Henda Draoui, Naceur El Marzouk, Emna Mehiri, Leila Slim-Saidi   +9 more
doaj   +1 more source

Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide.

, 2008
Mycobacterium tuberculosis is a facultative intracellular pathogen that inhibits phagosome maturation in macrophages thereby securing survival and growth.
Oschkinat, Hartmut, Stefan H. E. Kaufmann, Albert Haas, Enders, Jana, Jana Enders, Hartmut Oschkinat, Axelrod, Sofia, Brigitte Schlegel, Kaufmann, Stefan HE, Ulrich E. Schaible, Volker Brinkmann, Brinkmann, Volker, Schaible, Ulrich E, Haas, Albert, Sofia Axelrod, Schlegel, Brigitte   +15 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

IRON EXCHANGE IN MYCOBACTERIA [PDF]

, 2016
The review analyzes the major foreign publications on the iron exchange in mycobacteria for the recent years. The issues of iron absorption by tuberculous mycobacteria, its preservation and regulation of their metabolism have been reviewed.
M. P. Zharikova, V. G. Demikhov, V. L. Dobin   +2 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source