Results 11 to 20 of about 165,721 (325)

Nontuberculous Mycobacteria-Overview

Microbiology Spectrum, 2017
ABSTRACT Nontuberculous mycobacteria (NTM) are emerging pathogens that affect both immunocompromised and immunocompetent patients. The development of molecular methods has allowed the characterization of new species and the identification of NTM to the precise species and subspecies levels.
W. Koh
openaire   +3 more sources

MmpL3 is the flippase for mycolic acids in mycobacteria [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2017
The defining feature of the mycobacterial outer membrane (OM) is the presence of mycolic acids (MAs), which, in part, render the bilayer extremely hydrophobic and impermeable to external insults, including many antibiotics.
Chng, Shu-Sin, Meshcheryakov, Vladimir A., Poce, Giovanna, Xu, Zhujun   +3 more
core   +2 more sources

Global trends of pulmonary infections with nontuberculous mycobacteria: a systematic review.

International Journal of Infectious Diseases, 2022
OBJECTIVES To describe global trends of pulmonary nontuberculus mycobacteria (NTM) infection and disease. METHODS A systematic review of studies including culture-based NTM data over time.
V. Dahl, M. Mølhave, A. Fløe, Prof Jakko van Ingen, Prof Thomas Schön, Prof Troels Lillebaek, Prof Aase Bengaard Andersen, Prof Christian Wejse   +7 more
semanticscholar   +1 more source

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria

Cell, 2023
Summary Inborn errors of human IFN-γ-dependent macrophagic immunity underlie mycobacterial diseases, whereas inborn errors of IFN-α/β-dependent intrinsic immunity underlie viral diseases. Both types of IFNs induce the transcription factor IRF1.
J. Rosain, Anna-Lena Neehus, J. Manry, Rui Yang, J. Le Pen, W. Daher, Zhiyong Liu, Yi-Hao Chan, Natalia Tahuil, Ö. Türel, Mathieu Bourgey, Masato Ogishi, Jean-Marc Doisne, Helena M. Izquierdo, Takayoshi Shirasaki, T. Le Voyer, Antoine Guérin, P. Bastard, M. Moncada-Vélez, Ji Eun Han, Taushif Khan, F. Rapaport, Seon-Hui Hong, Andrew M Cheung, Kathrin Haake, Barbara C. Mindt, Laura Pérez, Q. Philippot, Danyel Lee, Peng Zhang, Darawan Rinchai, F. Al Ali, Manar Mahmoud Ahmad Ata, M. Rahman, Jessica N. Peel, Søren Heissel, Henrik Molina, Yasemin Kendir-Demirkol, Rasheed Bailey, Shuxiang Zhao, J. Bohlen, Mathieu Mancini, Y. Seeleuthner, M. Roelens, Lazaro Lorenzo, Camille Soudée, M. Paz, M. González, M. Jeljeli, Jean Soulier, Serge Romana, A-S. L’Honneur, M. Materna, Rubén Martínez-Barricarte, Mathieu Pochon, Carmen Oleaga-Quintas, Alexandre Michev, M. Migaud, R. Lévy, M. Alyanakian, Flore Rozenberg, Carys A. Croft, Guillaume Vogt, Jean-François Emile, Laurent Kremer, Cindy S. Ma, Jörg H. Fritz, Stanley M. Lemon, A. Spaan, Nicolas Manel, L. Abel, Margaret R MacDonald, S. Boisson-Dupuis, N. Marr, S. Tangye, J. D. Di Santo, Qian Zhang, Shen-Ying Zhang, Charles M. Rice, V. Béziat, Nico Lachmann, D. Langlais, J. Casanova, P. Gros, J. Bustamante   +84 more
semanticscholar   +1 more source

Drug Resistance in Nontuberculous Mycobacteria: Mechanisms and Models

Biology, 2021
Simple Summary Recently, there has been a considerable rise in infections caused by nontuberculous mycobacteria (NTM). These mycobacteria, which comprise a large and diverse range of species, have developed resistance to most conventional antibiotics ...
S. Saxena, H. Spaink, G. Forn-Cuní
semanticscholar   +1 more source

Ecology of Nontuberculous Mycobacteria

Microorganisms, 2021
Nontuberculous mycobacteria (NTM) are opportunistic human pathogens that are widespread in the human environment. In fact, NTM surround humans. The basis for their widespread presence in soils and natural and human-engineered waters lies primarily in ...
J. Falkinham
semanticscholar   +1 more source

Mycobacteria

Microbiology Spectrum, 2016
ABSTRACT The immunocompromised host is at increased risk of Mycobacterium tuberculosis complex and nontuberculous mycobacteria infection. Although Mycobacterium tuberculosis complex is a significant mycobacterial pathogen, nontuberculous mycobacteria causes substantial disease in ...
Patricia J, Simner, Gail L, Woods, Nancy L, Wengenack   +2 more
openaire   +3 more sources

General Overview of Nontuberculous Mycobacteria Opportunistic Pathogens: Mycobacterium avium and Mycobacterium abscessus

Journal of Clinical Medicine, 2020
Nontuberculous mycobacteria (NTM) are emerging human pathogens, causing a wide range of clinical diseases affecting individuals who are immunocompromised and who have underlying health conditions.
K. To, Ruoqiong Cao, Aram Yegiazaryan, James Owens, V. Venketaraman   +4 more
semanticscholar   +1 more source

Performance and impact of GeneXpert MTB/RIF® and Loopamp MTBC Detection Kit® assays on tuberculosis case detection in Madagascar

BMC Infectious Diseases, 2019
Background Tuberculosis rapid molecular assays, including GeneXpert MTB/RIF® and Loopamp MTBC Detection Kit®, are highly sensitive and specific. Such performance does not automatically translate in improved disease control and highly depends on their use,
Niaina Rakotosamimanana, Simon Grandjean Lapierre, Vaomalala Raharimanga, Mamy Serge Raherison, Astrid M. Knoblauch, Antso Hasina Raherinandrasana, Andrianantenaina Rakotoson, Julio Rakotonirina, Voahangy Rasolofo   +8 more
doaj   +1 more source

No ntuberculous Mycobacteria

BIOpreparations. Prevention, Diagnosis, Treatment, 2020
There has been a sharp increase in the number of diseases associated with potentially pathogenic microorganisms of the genus Mycobacterium, which differ from Mycobacterium tuberculosis. These bacteria are known as atypical mycobacteria or nontuberculosis
M. Makarova, L. Guntupova
semanticscholar   +1 more source