Results 11 to 20 of about 77,428 (296)

Mycobacteria and TB [PDF]

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2002
Tuberculosis as a Global Public Health Problem, D.A. Enarson New Perspectives in the Molecular Epidemiology of Tuberculosis, D. van Soolingen, K. Kremer, E. Vynycky Vaccination - The Current Status of BCG, C.J. Clements Laboratory Diagnosis of Tuberculosis, G.E. Pfyffer Mycobacteria and TB - Therapy and Drug Resistance, S. Niemann, S.
KAUFMANN, Stefan H.E., HAHN, Helmut
openaire   +5 more sources

Genome-Wide Association Studies (GWAS) Approaches for the Detection of Genetic Variants Associated with Antibiotic Resistance: A Systematic Review

open access: yesMicroorganisms, 2023
Antibiotic resistance is a significant threat to public health worldwide. Genome-wide association studies (GWAS) have emerged as a powerful tool to identify genetic variants associated with this antibiotic resistance.
Jeanneth Mosquera-Rendón   +3 more
doaj   +1 more source

Mycobacteria

open access: yesMicrobiology Spectrum, 2016
ABSTRACT The immunocompromised host is at increased risk of Mycobacterium tuberculosis complex and nontuberculous mycobacteria infection. Although Mycobacterium tuberculosis complex is a significant mycobacterial pathogen, nontuberculous mycobacteria causes substantial disease in ...
Patricia J, Simner   +2 more
openaire   +2 more sources

Performance and impact of GeneXpert MTB/RIF® and Loopamp MTBC Detection Kit® assays on tuberculosis case detection in Madagascar

open access: yesBMC Infectious Diseases, 2019
Background Tuberculosis rapid molecular assays, including GeneXpert MTB/RIF® and Loopamp MTBC Detection Kit®, are highly sensitive and specific. Such performance does not automatically translate in improved disease control and highly depends on their use,
Niaina Rakotosamimanana   +8 more
doaj   +1 more source

Real-Time PCR for Molecular Detection of Zoonotic and Non-Zoonotic Giardia spp. in Wild Rodents

open access: yesMicroorganisms, 2021
Giardiasis in humans is a gastrointestinal disease transmitted by the potentially zoonotic Giardia duodenalis genotypes (assemblages) A and B. Small wild rodents such as mice and voles are discussed as potential reservoirs for G.
Christian Klotz   +4 more
doaj   +1 more source

Translational Rodent Models for Research on Parasitic Protozoa—A Review of Confounders and Possibilities

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Rodents, in particular Mus musculus, have a long and invaluable history as models for human diseases in biomedical research, although their translational value has been challenged in a number of cases.
Totta Ehret   +5 more
doaj   +1 more source

Acylation of glycerolipids in mycobacteria

open access: yesNature Communications, 2023
We report on the existence of two phosphatidic acid biosynthetic pathways in mycobacteria, a classical one wherein the acylation of the sn-1 position of glycerol-3-phosphate (G3P) precedes that of sn-2 and another wherein acylations proceed in the ...
Shiva Kumar Angala   +15 more
doaj   +1 more source

Proline Dehydrogenase and Pyrroline 5 Carboxylate Dehydrogenase from Mycobacterium tuberculosis: Evidence for Substrate Channeling

open access: yesPathogens, 2023
In Mycobacterium tuberculosis, proline dehydrogenase (PruB) and ∆1-pyrroline-5-carboxylate (P5C) dehydrogenase (PruA) are monofunctional enzymes that catalyze proline oxidation to glutamate via the intermediates P5C and L-glutamate-γ-semialdehyde.
Santosh Kumar   +6 more
doaj   +1 more source

Physiology of Mycobacteria [PDF]

open access: yes, 2009
Mycobacterium tuberculosis is a prototrophic, metabolically flexible bacterium that has achieved a spread in the human population that is unmatched by any other bacterial pathogen. The success of M. tuberculosis as a pathogen can be attributed to its extraordinary stealth and capacity to adapt to environmental changes throughout the course of infection.
Cook, Gregory M.   +6 more
openaire   +5 more sources

Mycobacteria and sarcoidosis [PDF]

open access: yesThorax, 1997
Background. Acid fast cell wall deficient forms (CWDF) of bacteria have been grown from blood, bronchial washings, and ocular anterior chamber fluid from patients with sarcoidosis. A monoclonal antibody raised against Mycobacterium tuberculosis whole cell antigen (H37RV) was used to characterise further CWDF grown from the blood of patients with ...
R M du Bois, O. M. Kon
openaire   +3 more sources

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