Results 21 to 30 of about 165,721 (325)

DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]

, 2010
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams, Afanasev, Alina E. Gorna, Aly, Arnold, Bacon, Banu, Bergval, Betts, Boshoff, Boshoff, Bostanabad, Burney, Capelli, Chan, Chan, Cheng, Cooper, Cubillos-Ruiz, Darwin, Darwin, Das, Davis, Dos Vultos, Dubnau, Durbach, Farnia, Fennelly, Filliol, Fleischmann, Flint, Fontan, Friedberg, Frischkorn, Fu, Fu, Gaynor, Gordhan, Graham, Grishko, Guthlein, Hampshire, Hazbon, Hughes, Jain, Jaroslaw Dziadek, Jiao, Kapur, Karakousis, Karakousis, Karunkaran, Katti, Kesavan, Kim, Ko, Ko, Korycka-Machala, Krokan, Kurthkoti, Kurthkoti, Lari, Lever, Loudon, MacMicking, Malshetty, Martinez, Mokrousov, Moller, Movahedzadeh, Mulder, Munoz-Elias, Muttucumaru, Nguyen, Niemann, Nikolayevskyy, Nouvel, O'sullivan, Olano, Peccia, Peccia, Pitcher, Rachman, Rachman, Rad, Ramaswamy, Richard P. Bowater, Riley, Saito, Sander, Sassetti, Sassetti, Saunders, Schnappinger, Schwab, Sherman, Sinha, Sinha, Smeulders, Springer, Srivastava, Stephanou, Talaat, Talaat, Tang, Tsai, Venkatesh, Vilcheze, Voskuil, Voskuil, Waddell, Wanner, Warner, Weikert, Wiid, Wiseman, World Health Organization, Zaczek, Zainuddin   +117 more
core   +1 more source

Translational Rodent Models for Research on Parasitic Protozoa—A Review of Confounders and Possibilities

Frontiers in Cellular and Infection Microbiology, 2017
Rodents, in particular Mus musculus, have a long and invaluable history as models for human diseases in biomedical research, although their translational value has been challenged in a number of cases.
Totta Ehret, Totta Ehret, Francesca Torelli, Christian Klotz, Amy B. Pedersen, Frank Seeber   +5 more
doaj   +1 more source

Expression of in vivo biotinylated recombinant antigens SAG1 and SAG2A from Toxoplasma gondii for improved seroepidemiological bead-based multiplex assays

BMC Biotechnology, 2020
Background Few bead-based multiplex assays have been described that detect antibodies against the protozoan parasite Toxoplasma gondii in large-scale seroepidemiological surveys. Moreover, each multiplex assay has specific variations or limitations, such
Sandra Klein, Daniel Stern, Frank Seeber
doaj   +1 more source

Genome-Wide Association Studies (GWAS) Approaches for the Detection of Genetic Variants Associated with Antibiotic Resistance: A Systematic Review

Microorganisms, 2023
Antibiotic resistance is a significant threat to public health worldwide. Genome-wide association studies (GWAS) have emerged as a powerful tool to identify genetic variants associated with this antibiotic resistance.
Jeanneth Mosquera-Rendón, Claudia Ximena Moreno-Herrera, Jaime Robledo, Uriel Hurtado-Páez   +3 more
doaj   +1 more source

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis

Disease Models & Mechanisms, 2015
Cost-effective animal models that accurately reflect the pathological progression of pulmonary tuberculosis are needed to screen and evaluate novel tuberculosis drugs and drug regimens.
Scott M. Irwin, Emily Driver, Edward Lyon, Christopher Schrupp, Gavin Ryan, Mercedes Gonzalez-Juarrero, Randall J. Basaraba, Eric L. Nuermberger, Anne J. Lenaerts   +8 more
doaj   +1 more source

An immunocompromised dialysis patient with skin and bone lesions [PDF]

, 2010
Patients with chronic kidney failure have disturbances of immune function involving both innate and adaptive systems. These result in both immunodepression which increases susceptibility to infection and immunoactivation leading to a chronic inflammatory
Brown, Griffith, Jarzembowski, Katoch, Swenson, Uslan, Wallace, Wallace   +7 more
core   +2 more sources

Rapid method for Mycobacterium tuberculosis identification using electrospray ionization tandem mass spectrometry analysis of mycolic acids [PDF]

, 2013
Mycolic acids (MAs), which play a crucial role in the architecture of mycobacterial cell walls, were analyzed using electrospray ionization tandem mass spectrometry. A targeted analysis based on the 10 most abundant and characteristic multiple reaction
Beata Janiszewska-Drobinska, Behr, Beukes, Brennan, Butler, Centers for Disease Control & Prevention (CDC), Chang, Daley, Deng, Dorman, Drobniewski, El Khéchine, Fujiwara, Jafari, Konrad Kowalski, Kowalski, Lawn, Lotz, Magdalena Druszczyńska, Ottenhoff, Park, Rafał Szewczyk, Saleeb, Schluger, Shitikov, Shui, Shui, Siddiqi, Song, Steingart, Takayama, Toney, Tostmann, Viader-Salvadó, Vittor, Wang, World Health Organization (WHO), Yassin, Yuan   +38 more
core   +1 more source

Real-Time PCR for Molecular Detection of Zoonotic and Non-Zoonotic Giardia spp. in Wild Rodents

Microorganisms, 2021
Giardiasis in humans is a gastrointestinal disease transmitted by the potentially zoonotic Giardia duodenalis genotypes (assemblages) A and B. Small wild rodents such as mice and voles are discussed as potential reservoirs for G.
Christian Klotz, Elke Radam, Sebastian Rausch, Petra Gosten-Heinrich, Toni Aebischer   +4 more
doaj   +1 more source

Mycobacterial panniculitis caused by Mycobacterium thermoresistibile in a cat. [PDF]

, 2016
Case summaryA domestic shorthair cat was evaluated for chronic, bilateral, ulcerative dermatitis affecting the inguinal region and lateral aspects of both pelvic limbs.
Keel, M Kevin, Reagan, Krystle L, Sykes, Jane E, Vishkautsan, Polina   +3 more
core   +2 more sources

From Entry to Early Dissemination—Toxoplasma gondii's Initial Encounter With Its Host

Frontiers in Cellular and Infection Microbiology, 2019
Toxoplasma gondii is a zoonotic intracellular parasite, able to infect any warm-blooded animal via ingestion of infective stages, either contained in tissue cysts or oocysts released into the environment.
Estefania Delgado Betancourt, Benjamin Hamid, Benedikt T. Fabian, Christian Klotz, Susanne Hartmann, Frank Seeber   +5 more
doaj   +1 more source