Results 121 to 130 of about 50,263 (294)

Target Analysis and Retrospective Screening of Multiple Mycotoxins in Pet Food Using UHPLC-Q-Orbitrap HRMS

, 2019
A comprehensive strategy combining a quantitative method for 28 mycotoxins and a post-target screening for other 245 fungal and bacterial metabolites in dry pet food samples were developed using an acetonitrile-based extraction and an ultrahigh ...
Luigi Castaldo, Luana Izzo, Yelko Rodríguez-Carrasco, Alberto Ritieni, Anna Gaspari, Josefa Tolosa, Giulia Graziani   +6 more
core   +1 more source

Contamination of Pet Food with Mycobiota and Fusarium Mycotoxins—Focus on Dogs and Cats

, 2020
A wide range of pet food types are available on the market; the dominant type is dry food formulated in croquets. One of the most common ingredients of dry food are cereals—vectors of harmful mycotoxins posing the risk to pet health. In this study,
Natalia Witaszak, Łukasz Stępień, Agnieszka Waśkiewicz, Jan Bocianowski   +3 more
core   +1 more source

Environmental Mycotoxins and Brain Health: Protective Role of Bromelain Against Fumonisin B1 in SH‐SY5Y Cells

Environmental Toxicology, EarlyView.
ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco, Francesca Inferrera, Nicla Tranchida, Davide Di Paola, Roberta Fusco, Salvatore Cuzzocrea, Enrico Gugliandolo   +6 more
wiley   +1 more source

Effective preparation of a monoclonal antibody against human chromogranin A for immunohistochemical diagnosis

BMC Biotechnology, 2018
Background Human chromogranin A (CgA) is a ~ 49 kDa secreted protein mainly from neuroendocrine cells and endocrine cells. The CgA values in the diagnosis of tumor, and in the potential role in prognostic and predictive tumor as a biomarker.
Danping Zhang, Chengjie Xie, Rongzhi Wang, Qinghai Yang, Huiling Chen, Sumei Ling, Shihua Wang, Kunzhi Jia   +7 more
doaj   +1 more source

Simultaneous Determination of Twenty Mycotoxins in the Korean Soybean Paste Doenjang by LC-MS/MS with Immunoaffinity Cleanup

, 2019
Doenjang, a Korean fermented soybean paste, is vulnerable to contamination by mycotoxins because it is directly exposed to environmental microbiota during fermentation.
Sang Yoo Lee, So Young Ryu, Fei Tian, Hyang Sook Chun, Su Been Park, So Young Woo   +5 more
core   +1 more source

Establishment of a Human Cell‐Based In Vitro Test System for Investigating and Evaluating Cytotoxic and Immunomodulatory Effects of Indoor Mold

Environmental Toxicology, EarlyView.
ABSTRACT Mold growth in damp indoor environments is a widespread problem associated with respiratory health effects, though causal mechanisms remain incompletely understood. We established a human cell‐based in vitro test system using bronchial epithelial cells (NuLi‐1) and macrophages (THP‐1) to assess inhalation toxicity and immunomodulatory effects ...
Anja Wolff, Jessica Reinert, Silke Steinborn, Marion Berger, Judith Neuhoff, Lennart Marske, Kerttu Valtanen, Udo Jäckel, Stefanie Klar   +8 more
wiley   +1 more source

The role of Npt1 in regulating antifungal protein activity in filamentous fungi

Nature Communications
Pathogenic filamentous fungi pose a significant threat to global food security and human health. The limitations of available antifungal agents, including resistance and toxicity, highlight the need for developing innovative antifungal strategies ...
Yu Wang, Sen Wang, Yuanyuan Chen, Chunlan Xie, Haibo Xu, Yunhua Lin, Ranxun Lin, Wanlin Zeng, Xuan Chen, Xinyi Nie, Shihua Wang   +10 more
doaj   +1 more source

STA regulates succinylated AflM triggered by SCS to contribute to aflatoxin biosynthesis through the Ach1

Virulence
Aspergillus flavus and its secondary metabolites, aflatoxins (AFs), especially aflatoxin B1 (AFB1), seriously affect agricultural production, food storage, and human health.
Rui Xie, Zhenhong Zhuang, Qionghui Chen, Chunlan Xie, John Adejor, Xinyi Nie, Shihua Wang   +6 more
doaj   +1 more source

Two‐Dimensional Materials For Lateral Flow Assays: A Critical Review of Functional Roles and Translational Challenges

VIEW, EarlyView.
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu, Ruping Liu, Na Gao, Jianxiao Zhu, Haowen Jiang, Shouzheng Jiao, Zhicheng Sun, Kai Shen, Gaolian Xu, Minghua Du, Ziyan Li, Yang Wang   +11 more
wiley   +1 more source

Presence of 19 Mycotoxins in Human Plasma in a Region of Northern Spain

, 2020
This study was conducted to investigate human exposure to 19 compounds (mycotoxins and their metabolites) in plasma samples from healthy adults (n = 438, aged 19–68 years) from Navarra, a region of northern Spain. Samples were analyzed by LC-MS/MS,
Ángel Irigoyen, Beatriz Arce-López, Elena González-Peñas, Elena Lizarraga   +3 more
core   +1 more source