Results 21 to 30 of about 85,956 (299)
Filtered Kombucha Tea Rings the Bell for TLR2, TLR4, MYD88, and Dectin-1 in Mice Model of Colitis [PDF]
Research Journal of Pharmacognosy, 2020 Background and objectives: TLR2, TLR4, and Dectin-1 (Clec7) are pattern recognition receptors (PRRs) expressed by intestinal epithelia cells and MYD88 is a signaling molecule of TLR2 and TLR4.
Elaheh Mahmoudi* +2 more
doaj +1 more source
Journal of food biochemistry, 2021 Although astragaloside IV protects from acute myocardial infarction (AMI)-induced chronic heart failure (CHF), the underlying mechanism of action is unclear.
Hui Shi +8 more
semanticscholar +1 more source
Autoimmunity, 2021 Infantile pneumonia is a common inflammatory disease with the infections of various pathogens in lower respiratory tracts. Here, the role and working mechanism of circular RNA (circRNA) ubiquinol-cytochrome c reductase core protein 2 (circ-UQCRC2 ...
Xuan Zhang, Chunbao Chen, Bei Li, Wei Lu
doaj +1 more source
British Journal of Haematology, 2021 Reliable biomarkers are needed to avoid diagnostic delay and its devastating effects in patients with primary central nervous system (CNS) lymphoma (PCNSL).
A. Ferreri +33 more
semanticscholar +1 more source
A Novel Kindred with MyD88 Deficiency
Journal of Clinical Immunology, 2022 sponsorship: IM is a senior clinical investigator at the Research Foundation - Flanders (FWO) and is supported by the CSL Behring Chair of Primary Immunodeficiencies; by a KU Leuven C1 Grant [grant number C16/18/007]; by a VIB GC PID Grant; by the Research Foundation -Flanders (FWO) [grant numbers G0C8517N, G0B5120N, and G0E8420N]; and by the Jeffrey ...
Bucciol, Giorgia +4 more
openaire +4 more sources
MyD88: At the Heart of Inflammatory Signaling and Cardiovascular Disease
Journal of Molecular and Cellular Cardiology, 2021 Cardiovascular disease is a leading cause of death worldwide and is associated with systemic inflammation. In depth study of the cell-specific signaling mechanisms mediating the inflammatory response is vital to improving anti-inflammatory therapies that
Abraham L. Bayer, P. Alcaide
semanticscholar +1 more source
Immunity, 2008 In this issue of Immunity, Hou et al. (2008) describe the generation of mice that selectively lack the adaptor protein MyD88 in dendritic cells (DCs). These mice demonstrate that the requirement for Toll-like receptor (TLR) signaling in DCs is dependent on the physical form of the TLR ligand.
Pulendran, Bali, Cao, Weiping
openaire +2 more sources
Nature Communications, 2021 MyD88 and MAL are Toll-like receptor (TLR) adaptors that signal to induce pro-inflammatory cytokine production. We previously observed that the TIR domain of MAL (MALTIR) forms filaments in vitro and induces formation of crystalline higher-order ...
Max T. B. Clabbers +24 more
semanticscholar +1 more source
TLR4 knockdown by miRNA-140-5p improves tendinopathy: an in vitr o study
Archives of Medical Science, 2020 Introduction The purpose of this study was to determine whether TLR4 knockdown induced by miRNA-140-5p improves tendinopathy in an in vitro experiment. Material and methods Extraction of tendon-derived stem cells (TDSCs) from SD rats was performed using
Tu Jun, Guo Ruipeng, Xu Bin
doaj +1 more source
Redox Report, 2021 Objectives The study explores the protective role of the peripheral serum of limb remote ischemic postconditioning (LRIP) in reducing the reactive oxygen species (ROS) levels and neutrophil activation, which are responsible for the deleterious ...
Gangling Chen +7 more
doaj +1 more source