Results 41 to 50 of about 300,317 (388)

Confined Multilamellae Prefer Cylindrical Morphology [PDF]

open access: yes, 2005
By evaporating a drop of lipid dispersion we generate the myelin morphology often seen in dissolving surfactant powders. We explain these puzzling nonequilibrium structures using a geometric argument: The bilayer repeat spacing increases and thus the ...
Huang, Jung-Ren   +2 more
core   +1 more source

TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis

open access: yesActa Neuropathologica, 2020
Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS) triggered by autoimmune mechanisms.
Francesca Cignarella   +19 more
semanticscholar   +1 more source

Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System

open access: yesFrontiers in Neuroscience, 2019
In this review, we draw attention to the roles of calcitriol (1,25-dihydroxyvitamin D3) in the trophicity of the peripheral nervous system. Calcitriol has long been known to be crucial in phosphocalcium homeostasis. However, recent discoveries concerning
Pierre Antoine Faye   +11 more
doaj   +1 more source

RNASET2-deficient leukoencephalopathy mimicking congenital CMV infection and Aicardi-Goutieres syndrome: a case report with a novel pathogenic variant

open access: yesOrphanet Journal of Rare Diseases, 2019
Background Ribonucleases (RNases) are crucial for degradation of ribosomal RNA (rRNA). RNASET2 as a subtype of RNASEs is a 256 amino acid protein, encoded by RNASET2 gene located on chromosome six.
Reyhaneh Kameli   +9 more
doaj   +1 more source

An atlas for human brain myelin content throughout the adult life span

open access: yesScientific Reports, 2021
Myelin water imaging is a quantitative neuroimaging technique that provides the myelin water fraction (MWF), a metric highly specific to myelin content, and the intra-/extra-cellular T 2 (IET2), which is related to water and iron content. We coupled high-
A. Dvorak   +15 more
semanticscholar   +1 more source

Polarization and Myelination in Myelinating Glia [PDF]

open access: yesISRN Neurology, 2012
Myelinating glia, oligodendrocytes in central nervous system and Schwann cells in peripheral nervous system, form myelin sheath, a multilayered membrane system around axons enabling salutatory nerve impulse conduction and maintaining axonal integrity.
openaire   +2 more sources

Myelin pathology: Involvement of molecular chaperones and the promise of chaperonotherapy [PDF]

open access: yes, 2019
The process of axon myelination involves various proteins including molecular chaperones. Myelin alteration is a common feature in neurological diseases due to structural and functional abnormalities of one or more myelin proteins.
Cappello F.   +4 more
core   +1 more source

Bilateral horizontal gaze palsy in an 8‐year‐old girl: A rare case with NDUFS4 gene mutation

open access: yesClinical Case Reports, 2021
We report a patient with complex clinical presentation including multiple neurological symptoms and eye involvement. Upon genetic investigation, the patient was found to carry a novel homozygous mutation in the NDUFS4 gene, thus adding to the ...
Mohammad Vafaee‐Shahi   +6 more
doaj   +1 more source

Myelin Fat Facts: An Overview of Lipids and Fatty Acid Metabolism

open access: yesCells, 2020
Myelin is critical for the proper function of the nervous system and one of the most complex cell–cell interactions of the body. Myelination allows for the rapid conduction of action potentials along axonal fibers and provides physical and trophic ...
Y. Poitelon   +2 more
semanticscholar   +1 more source

Disruption of Sema3A/Plexin‐A1 inhibitory signalling in oligodendrocytes as a therapeutic strategy to promote remyelination

open access: yesEMBO Molecular Medicine, 2019
Current treatments in multiple sclerosis (MS) are modulating the inflammatory component of the disease, but no drugs are currently available to repair lesions.
Fabien Binamé   +12 more
doaj   +1 more source

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