Results 21 to 30 of about 108,243 (307)
Lipid and basic protein interaction in myelin [PDF]
Biochemical Journal, 1974 1. Purified myelin labelled with [3H]myo-inositol or [1-14C]acetate was incubated with trypsin or acetylated trypsin at 37°C, pH8.0 for 30min. 2. After incubation and centrifugation analysis of the myelin pellet showed marked digestion of basic protein on polyacrylamide-gel electrophoresis. Proteolipid and Wolfgram proteins remained unchanged. 3.
Naren L. Banik, Alan N. Davison
openaire +3 more sources
Phosphorylation of Myelin Basic Protein
Journal of Biological Chemistry, 1974 Myelin membranes prepared from rat brain possess both the enzyme and substrates to incorporate 32P from [γ-32P]ATP into membrane protein constituents. Of the myelin polypeptides, only the two basic proteins were phosphorylated; and both components appeared to be equally good substrates for endogenous or added protein kinases.
Andreas J. Steck, Stanley H. Appel
openaire +3 more sources
Non-Thermal Mechanism of Weak Microwave Fields Influence on Nerve Fiber [PDF]
J. Appl. Phys. 114, 104701 (2013), 2013 We propose a non-thermal mechanism of weak microwave field impact on a nerve fiber. It is shown that in the range of about 30 - 300 GHz there are strongly pronounced resonances associated with the excitation of ultrasonic vibrations in the membrane as a result of interaction with electromagnetic radiation.
arxiv +1 more source
Chronic Stress, 2018 Background Astrocytes and oligodendrocytes are pathologically altered in dorsolateral prefrontal and orbitofrontal cortices in major depressive disorder.
José Javier Miguel-Hidalgo +3 more
doaj +1 more source
Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases
Cell Reports, 2016 Breakdown of myelin sheaths is a pathological hallmark of several autoimmune diseases of the nervous system. We employed autoantibody-mediated animal models of demyelinating diseases, including a rat model of neuromyelitis optica (NMO), to target myelin ...
Marie-Theres Weil +13 more
doaj +1 more source
Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]
arXiv, 2022 Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv
A space-fractional cable equation for the propagation of action potentials in myelinated neurons [PDF]
Emerging Science Journal, Vol. 4, No. 3: 148-164, 2020, 2020 Myelinated neurons are characterized by the presence of myelin, a multilaminated wrapping around the axons formed by specialized neuroglial cells. Myelin acts as an electrical insulator and therefore, in myelinated neurons, the action potentials do not propagate within the axons but happen only at the nodes of Ranvier which are gaps in the axonal ...
arxiv +1 more source
Laboratory Animal Research, 2017 Myelin degeneration is one of the characteristics of aging and degenerative diseases. This study investigated age-related alterations in expression of myelin basic protein (MBP) in the hippocampal subregions (dentate gyrus, CA2/3 and CA1 areas) of ...
Ji Hyeon Ahn +11 more
doaj +1 more source
Epilepsia Open, EarlyView., 2022 Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica +6 more
wiley +1 more source
Central and peripheral dysmyelination in a 3‐year‐old girl with ring chromosome 18
Clinical Case Reports, 2019 Myelin basic protein (MBP) contributes to peripheral and central nervous system myelin. Developmental myelinopathies exist on a clinical spectrum, but MBP is not included on leukodystrophy or CMT gene panels.
Dawn Brianna Lammert +6 more
doaj +1 more source