Results 21 to 30 of about 107,221 (257)
Advances in the pathogenesis of Rett syndrome using cell models
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 532-541, December 2022., 2022 Most Rett syndrome (RTT) patients are affected by the MECP2 gene mutations. And the mutations of MECP2 have wide effects on different cell types of nervous system, including neurons, astrocytes, oligodendrocytes and microglia, which always combined together to lead to abnormalities in the whole neural network.
Sijia Lu, Yongchang Chen, Zhengbo Wang
wiley +1 more source
Non-Thermal Mechanism of Weak Microwave Fields Influence on Nerve Fiber [PDF]
J. Appl. Phys. 114, 104701 (2013), 2013 We propose a non-thermal mechanism of weak microwave field impact on a nerve fiber. It is shown that in the range of about 30 - 300 GHz there are strongly pronounced resonances associated with the excitation of ultrasonic vibrations in the membrane as a result of interaction with electromagnetic radiation.
arxiv +1 more source
Chronic Stress, 2018 Background Astrocytes and oligodendrocytes are pathologically altered in dorsolateral prefrontal and orbitofrontal cortices in major depressive disorder.
José Javier Miguel-Hidalgo +3 more
doaj +1 more source
Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases
Cell Reports, 2016 Breakdown of myelin sheaths is a pathological hallmark of several autoimmune diseases of the nervous system. We employed autoantibody-mediated animal models of demyelinating diseases, including a rat model of neuromyelitis optica (NMO), to target myelin ...
Marie-Theres Weil +13 more
doaj +1 more source
Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]
arXiv, 2022 Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv
Laboratory Animal Research, 2017 Myelin degeneration is one of the characteristics of aging and degenerative diseases. This study investigated age-related alterations in expression of myelin basic protein (MBP) in the hippocampal subregions (dentate gyrus, CA2/3 and CA1 areas) of ...
Ji Hyeon Ahn +11 more
doaj +1 more source
Central and peripheral dysmyelination in a 3‐year‐old girl with ring chromosome 18
Clinical Case Reports, 2019 Myelin basic protein (MBP) contributes to peripheral and central nervous system myelin. Developmental myelinopathies exist on a clinical spectrum, but MBP is not included on leukodystrophy or CMT gene panels.
Dawn Brianna Lammert +6 more
doaj +1 more source
A space-fractional cable equation for the propagation of action potentials in myelinated neurons [PDF]
Emerging Science Journal, Vol. 4, No. 3: 148-164, 2020, 2020 Myelinated neurons are characterized by the presence of myelin, a multilaminated wrapping around the axons formed by specialized neuroglial cells. Myelin acts as an electrical insulator and therefore, in myelinated neurons, the action potentials do not propagate within the axons but happen only at the nodes of Ranvier which are gaps in the axonal ...
arxiv +1 more source
CONTENTS OF SERUM MYELIN BASIC PROTEIN-IGG ANTIBODIES COMPLEXES IN NORMAL PREGNANCY AND GESTOSIS
Медицинская иммунология, 2014 Serum levels of myelin basic protein (MBP)-bound immune complexes were studied in blood sera from women with gestosis, as compared with those in normal pregnancy and non-pregnant woman.
V. G. Levchenko +4 more
doaj +1 more source
Journal of Comparative Neurology, Volume 531, Issue 2, Page 314-335, February 2023., 2023 The main objective of this work was to obtain detailed information on the distribution and localization of the spexin (Spx) system in the sea bass brain. To this purpose, we first identified and characterized the spx1 gene and analyzed its expression in the central nervous system (CNS) of the European sea bass by using quantitative Real‐Time Polymerase
José A. Paullada‐Salmerón +2 more
wiley +1 more source