Results 21 to 30 of about 163,909 (218)

Characteristics of myelin oligodendrocyte glycoprotein antibody-associated meningoencephalitis. [PDF]

Mult Scler J Exp Transl Clin
Background Meningoencephalitis can occur in myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD). Objective To assess the clinical and radiologic features of MOG-IgG meningoencephalitis.
Elfasi A, Alkabie S, Rodriguez E, Montalvo M, Castrodad-Molina R, Cuascut FX, Hutton GJ, Kinkel R, Graves J, Rempe T.   +9 more
europepmc   +2 more sources

Invasive Multimodality Neuromonitoring to Manage Cerebral Edema in Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease

Critical Care Explorations, 2023
Background:. Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an inflammatory disorder of the CNS with a variety of clinical manifestations, including cerebral edema. Case Summary:.
Nina A. Fainberg, MD, Maya R. Silver, MD, John D. Arena, MD, Elizabeth I. Landzberg, MD, Brenda Banwell, MD, Claudia Gambrah-Lyles, MD, Matthew P. Kirschen, MD, PhD, Peter J. Madsen, MD, Loren McLendon, MD, Sona Narula, MD, Alexander M. Tucker, MD, Jimmy W. Huh, MD, Martha F. Kienzle, MD   +12 more
doaj   +1 more source

Analysis of probable predictors of aggressive multiple sclerosis

Бюллетень сибирской медицины, 2020
Objective: to study the probable laboratory predictors of aggressive multiple sclerosis.Materials and methods. Antibodies to myelin oligodendrocyte glycoprotein (MOG), antibodies to thyroperoxidase and markers of endothelial dysfunction in blood serum ...
N. N. Spirin, E. V. Kiseleva, N. N. Spirina   +2 more
doaj   +1 more source

A rare presentation of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) as acute hemorrhagic longitudinally extensive transverse myelitis

The Egyptian Journal of Radiology and Nuclear Medicine, 2023
Background Myelin oligodendrocyte glycoprotein antibody-associated disease is usually associated with optic neuritis, acute disseminated encephalomyelitis or transverse myelitis.
Aniket Nerlekar, Sharad Malvadkar, Dhairyasheel Patil, Bhagyashree Bhoir, Neha Shaikh, Jagdish Sambare   +5 more
doaj   +1 more source

Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more [PDF]

, 2012
B cells and antibodies constitute an important element in different inflammatory diseases of the central nervous system (CNS). Autoantibodies can serve as a biomarker to identify disease subgroups and may in addition contribute to the pathogenic process.
Mayer, Marie Cathrin, Meinl, Edgar, Marie Cathrin Mayer, Edgar Meinl, Meinl, E., Mayer, M.   +5 more
core   +1 more source

Mature and Myelinating Oligodendrocytes Are Specifically Vulnerable to Mild Fluid Percussion Injury in Mice

Neurotrauma Reports, 2023
Myelin loss and oligodendrocyte death are well documented in patients with traumatic brain injury (TBI), as well as in experimental animal models after moderate-to-severe TBI.
Alexandra A. Adams, Teresa L. Wood, Haesun A. Kim   +2 more
doaj   +1 more source

Differential expression and MAL-dependent targeting of the L-MAG and S-MAG isoforms to myelin membranes [PDF]

, 2003
Many degenerative diseases of the nervous system, including Multiple Sclerosis and peripheral neuropathies, are triggered by an impaired interaction between the axons and their surrounding myelin sheaths.
Erb, Michael
core   +1 more source

Neuroprotection in a Novel Mouse Model of Multiple Sclerosis [PDF]

, 2013
Multiple sclerosis is an immune-mediated, demyelinating and neurodegenerative disease that currently lacks any neuroprotective treatments. Innovative neuroprotective trial designs are required to hasten the translational process of drug development.
Coffey, P, Baker, MD, Coffey Pete, Jackson, SJ, Gavin Giovannoni, Baker David, Samuel J. Jackson (468645), Zubair Ahmed (9352), Jackson Samuel J., Zubair Ahmed, Ahmed, Z, Mark D Baker, Pete Coffey (422262), David Baker, Samuel J Jackson, Gavin Giovannoni (125820), Giovannoni Gavin, Munro Peter, Ahmed Zubair, Pete Coffey, David Baker (11642), Peter Munro (479715), Peter Munro, Lidster Katie, Baker Mark D., Baker, D, Lidster, K, Mark D. Baker (146531), Katie Lidster, Munro, P, Katie Lidster (479714), Giovannoni, G   +31 more
core   +1 more source

Synthesis of antagonists of Myelin-associated glycoprotein (MAG) for conformational and SAR studies [PDF]

, 2004
Damage to the central nervous system (CNS) of higher vertebrates, including humans, often results in devastating and persistent functional deficits.
Gao, Gan-Pan
core   +1 more source

Proteasome Biology Is Compromised in White Matter After Asphyxic Cardiac Arrest in Neonatal Piglets

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Neurological deficits in hypoxic‐ischemic encephalopathy, even with therapeutic hypothermia, are partially attributed to white matter injury. We theorized that proteasome insufficiency contributes to white matter injury.
Polan T. Santos, Caitlin E. O'Brien, May W. Chen, C. Danielle Hopkins, Shawn Adams, Ewa Kulikowicz, Rashmi Singh, Raymond C. Koehler, Lee J. Martin, Jennifer K. Lee   +9 more
doaj   +1 more source