Results 41 to 50 of about 163,909 (218)

Devic mouse: a spontaneous double-transgenic mouse model of human opticospinal multiple sclerosis and autoimmune T- B cell cooperation [PDF]

, 2007
Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system (CNS). Myelin antigen(s) specific T cells, B cells, and antibodies are thought to play a role in the pathogenesis of MS.
Krishnamoorthy, Gurumoorthy
core   +1 more source

Myelin oligodendrocyte glycoprotein antibody-associated disease as a novel presentation of central nervous system autoimmunity in a pediatric patient with Wiskott-Aldrich syndrome

Allergy, Asthma & Clinical Immunology, 2023
Background Wiskott-Aldrich syndrome (WAS) is an X-linked primary immunodeficiency caused by mutations in the WAS gene that leads to increased susceptibility to infections, thrombocytopenia, eczema, malignancies, and autoimmunity.
Vivien X. Xie, Wilson File, Christina Wiedl, Brant R. Ward, Blachy Dávila Saldaña, Michael D. Keller, Alexandra B. Kornbluh   +6 more
doaj   +1 more source

Case Report: Fundus findings in myelin oligodendrocyte glycoprotein-associated optic neuritis. [PDF]

Front Ophthalmol (Lausanne)
Myelin oligodendrocyte glycoprotein-associated optic neuritis (MOG-ON) is a sight-threatening demyelinating disorder that can present with various ocular manifestations.
Wilson JR, Cummings OW, Elitt MS, Van Stavern GP.   +3 more
europepmc   +2 more sources

Phenotypic characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in children: a single-center, retrospective study

Frontiers in Neurology, 2023
ObjectiveTo analyze the clinical characteristics and follow-up data of children with different clinical phenotypes of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).MethodsThe basic demographic and clinical features, laboratory ...
Yi Hua, Xuke Yan, Liu Liu, Yilong Wang, Lu Xu, Peifang Jiang, Zhefeng Yuan, Feng Gao   +7 more
doaj   +1 more source

Clinicopathological Features of Pakistani Patients with Myelin Oligodendrocyte Glycoprotein Antibody Associated Disease (MOGAD)

Pakistan Armed Forces Medical Journal
Objective: To characterize clinicopathological features of patients with Myelin Oligodendrocyte Glycoprotein Antibody Associated Disease in local population for early diagnosis and treatment. Study Design: Cross-sectional study.
Muhammad Zain Arshad, Muhammad Omair Riaz, Dawood Ahmad, Muhammad Hussain, Ayesha Tanveer, Maryam Bibi   +5 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A burning encephalitis: Fluid-attenuated inversion recovery-hyperintense lesions in Anti-myelin oligodendrocyte glycoprotein-associated encephalitis with seizures in anti-myelin oligodendrocyte glycoprotein-associated encephalitis with seizures—A case report and review of the literature

SAGE Open Medical Case Reports
FLAMES, or fluid-attenuated inversion recovery-hyperintense lesions in anti-myelin oligodendrocyte glycoprotein (anti-myelin oligodendrocyte glycoprotein)-associated encephalitis with seizures, represents a rarely documented syndrome characterized by ...
Ibtissam El Ouali, Amine Naggar, Kenza Berrada, Mohamed Jiddane, Firdaous Touarsa   +4 more
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Time-lapse imaging of the dynamics of CNS glial-axonal interactions in vitro and ex vivo [PDF]

, 2012
<b>Background</b> Myelination is an exquisite and dynamic example of heterologous cell-cell interaction, which consists of the concentric wrapping of multiple layers of oligodendrocyte membrane around neuronal axons.
Strachan, D., Susan C Barnett, Edgar Julia M., David Strachan (186501), Ioannidou, K., Julia M Edgar, Kurt I Anderson, Susan C. Barnett (186504), David Strachan, Julia M. Edgar (37537), Anderson, K.I., Barnett, S.C., Strachan David, Kalliopi Ioannidou, Kurt I. Anderson (186499), Edgar, J.M., Kalliopi Ioannidou (186497), Ioannidou Kalliopi, Anderson Kurt I., Barnett Susan C.   +19 more
core   +1 more source

Progressive myelin oligodendrocyte glycoprotein-associated demyelination mimicking leukodystrophy [PDF]

, 2022
Background: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) may be associated with relapsing disease, but clinical progression independent of relapse activity is rare.
Jacob, Anu, Rathi, Nitika, Avula, Shivaram, Elhadd, Kariem, Huda, Saif, Gibbons, Emily, Whittam, Daniel, Griffiths, Michael, Bhojak, Maneesh   +8 more
core   +1 more source