Results 231 to 240 of about 130,050 (381)

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

Glia, EarlyView.
ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley   +1 more source

AMX0035 Mitigates Oligodendrocyte Apoptosis and Ameliorates Demyelination in MCAO Rats by Inhibiting Endoplasmic Reticulum Stress and Mitochondrial Dysfunction. [PDF]

Int J Mol Sci
Zhang L, Bian C, Wang Y, Wei L, Sun S, Liu Q.   +5 more
europepmc   +1 more source

Analysis of transcription control elements of the moose myelin basic protein gene in HeLa cell extracts: demonstration of a strong NFI-binding motif in the upstream region

, 1988
Taka-aki Tamura, Masayuki Miura, Kazuhiro Ikenaka, Katsuhiko Mikoshiba   +3 more
openalex   +2 more sources

Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering. [PDF]

, 1992
Ariel Miller, Ofer Lider, Anita B. Roberts, Michael B. Sporn, Howard L. Weiner   +4 more
openalex   +1 more source

Impaired Volume Regulation and Electrophysiology of Astrocytes In Situ in a Mouse Model for Megalencephalic Leukoencephalopathy With Subcortical Cysts

Glia, EarlyView.
Cell culture studies show disrupted astrocyte physiology in the leukodystrophy MLC. Are intact astrocytes similarly affected? This study on astrocytes in MLC mouse brain slices confirms and extends in vitro studies on altered astrocyte physiology. ABSTRACT Electrical signaling, driven by ion fluxes between intra‐ and extracellular compartments, is ...
Sven Kerst, Nina Meesters, Tim S. Heistek, Marjo S. van der Knaap, Huibert D. Mansvelder, Rogier Min   +5 more
wiley   +1 more source

Basic Pathological Mechanisms in Peripheral Nerve Diseases. [PDF]

Int J Mol Sci
Schenone A, Massucco S, Schenone C, Venturi CB, Nozza P, Prada V, Pomili T, Di Patrizi I, Capodivento G, Nobbio L, Grandis M.   +10 more
europepmc   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

Tubulin Polymerization Promoting Proteins: Functional Diversity With Implications in Neurological Disorders. [PDF]

J Neurosci Res
Diaz PJ, Shi Q, McNeish PY, Banerjee S.
europepmc   +1 more source

An idiotype shared by monoclonal antibodies to different peptides of human myelin basic protein. [PDF]

, 1990
Shuang Zhou, John N. Whitaker
openalex   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source