Results 21 to 30 of about 130,050 (381)
Non-Thermal Mechanism of Weak Microwave Fields Influence on Nerve Fiber [PDF]
J. Appl. Phys. 114, 104701 (2013), 2013 We propose a non-thermal mechanism of weak microwave field impact on a nerve fiber. It is shown that in the range of about 30 - 300 GHz there are strongly pronounced resonances associated with the excitation of ultrasonic vibrations in the membrane as a result of interaction with electromagnetic radiation.
arxiv +1 more source
Recent Advances in Antigen-Specific Immunotherapies for the Treatment of Multiple Sclerosis
Brain Sciences, 2020 Multiple sclerosis (MS) is an autoimmune disease of the central nervous system and is considered to be the leading non-traumatic cause of neurological disability in young adults.
Olga Kammona, Costas Kiparissides
doaj +1 more source
MAG, myelin and overcoming growth inhibition in the CNS.
Frontiers in Molecular Neuroscience, 2015 While neurons in the central nervous system have the capacity to regenerate their axons after injury, they fail to do so, in part because regeneration is limited by growth inhibitory proteins present in CNS myelin.
Lisa eMcKerracher +2 more
doaj +1 more source
Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy [PDF]
, 2017 Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent of ...
Asadollahi, Ebrahim +17 more
core +3 more sources
Conformational transition of a myelin protein [PDF]
FEBS Letters, 1971 An interesting transition from conformation to p-structure has been reported for phosvitin [ 1, 21. Taborsky [l] found that the transition from random to &structure was induced by low pH (1.8) and was reversed by raising the pH. Perlman and Grizzuti [2] found that at pH 2.0 phosvitin had a /3-structure, while in the pH range 6.0-10.0 the ORD and CD ...
John Anthony, Mario A. Moscarello
openaire +3 more sources
Myelin activates FAK/Akt/NF-kappaB pathways and provokes CR3-dependent inflammatory response in murine system. [PDF]
PLoS ONE, 2010 Inflammatory response following central nervous system (CNS) injury contributes to progressive neuropathology and reduction in functional recovery. Axons are sensitive to mechanical injury and toxic inflammatory mediators, which may lead to demyelination.
Xin Sun +11 more
doaj +1 more source
The Multiple Roles of Myelin Protein Genes During the Development of the Oligodendrocyte
ASN Neuro, 2009 It has become clear that the products of several of the earliest identified myelin protein genes perform functions that extend beyond the myelin sheath. Interestingly, these myelin proteins, which comprise proteolipid protein, 2′, 3′-cyclic nucleotide 3′-
Daniel Fulton +2 more
doaj +1 more source
Neurology International, 2021 Hypomyelinating leukodystrophy 7 (HLD7) is an autosomal recessive oligodendroglial cell-related myelin disease, which is associated with some nucleotide mutations of the RNA polymerase 3 subunit a (polr3a) gene.
Sui Sawaguchi +7 more
doaj +1 more source
Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]
arXiv, 2022 Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv
Coronaviruses and Neuroantigens: myelin proteins, myelin genes [PDF]
, 2005 Multiple sclerosis (MS) is an autoimmune disease in which autoreactive T cells specific to central nervous system (CNS) myelin antigens are activated. Although disease etiology remains unknown, coronaviruses are suspected to be involved in MS pathology.
Pierre J. Talbot +3 more
openaire +1 more source