Results 41 to 50 of about 130,050 (381)
Citrullination – small change with a great consequence [PDF]
, 2013 Citrullination is one of the possible post-translational modifications of proteins. It is based on a conversion of L-arginine residue (L-Arg) to L-citrulline residue (L-Cit). The reaction is catalyzed by peptidylarginine deiminases (PAD). The change of L-
Gogól Mariusz
core +1 more source
Biochemistry Research International, 2023 In recent years, the pathogenetic role of oxidative stress in damaging myelin cells, a precursor to the development of myelin-related diseases such as multiple sclerosis, has gained increasing significance. Experimental autoimmune encephalomyelitis (EAE)
Gayane Ghazaryan +5 more
doaj +1 more source
Cells, 2022 Oligodendrocytes are the myelinating cells of the central nervous system. The physiological importance of oligodendrocytes is highlighted by diseases such as multiple sclerosis, in which the myelin sheaths are degraded and the axonal signal transmission ...
Juliane Bauch, Andreas Faissner
doaj +1 more source
Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis [PDF]
, 2013 PMCID: PMC3856490This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Amor, S +13 more
core +4 more sources
Chinese Journal of Contemporary Neurology and Neurosurgery, 2020 Objective To investigate the effect of Myriocin on high fat diet induced integrated stress response and further explore the mechanism. Methods A total of 18 ApoE-/-mice were fed a high⁃fat diet and randomly divided into control group (n=9, phosphate ...
Ze⁃mou YU +4 more
doaj
Molecular Mimicry of SARS-CoV-2 Spike Protein in the Nervous System: A Bioinformatics Approach
Computational and Structural Biotechnology Journal, 2022 Introduction: The development of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in record time to cope with the ongoing coronavirus disease 2019 (COVID-19) pandemic has led to uncertainty about their use and the appearance ...
Andrés Felipe Cuspoca +2 more
doaj
Packing of Myelin Protein Zero [PDF]
Neuron, 1996 Warner et al. 1996xWarner, L.E, Hilz, M.J, Appel, S.H, Killan, J.M, Kolodny, E.H, Karpati, G, Carpenter, S, Watters, G.V, Wheeler, C, Witt, D, Bodell, A, Nelis, E, Broeckhoven, C.V, and Lupski, J.R. Neuron. 1996; 17Abstract | Full Text | Full Text PDF | PubMed | Scopus (298)See all ReferencesWarner et al.
openaire +3 more sources
Proteasome Biology Is Compromised in White Matter After Asphyxic Cardiac Arrest in Neonatal Piglets
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Neurological deficits in hypoxic‐ischemic encephalopathy, even with therapeutic hypothermia, are partially attributed to white matter injury. We theorized that proteasome insufficiency contributes to white matter injury.
Polan T. Santos +9 more
doaj +1 more source
Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5
eLife, 2022 Oligodendrocytes facilitate rapid impulse propagation along the axons they myelinate and support their long-term integrity. However, the functional relevance of many myelin proteins has remained unknown.
Tobias J Buscham +16 more
doaj +1 more source
gACSON software for automated segmentation and morphology analyses of myelinated axons in 3D electron microscopy [PDF]
arXiv, 2021 Background and Objective: Advances in electron microscopy (EM) now allow three-dimensional (3D) imaging of hundreds of micrometers of tissue with nanometer-scale resolution, providing new opportunities to study the ultrastructure of the brain. In this work, we introduce a freely available Matlab-based gACSON software for visualization, segmentation ...
arxiv