Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension [PDF]
Myelin is essential for rapid nerve signaling and is increasingly found to play important roles in learning and in diverse diseases of the CNS. Morphological parameters of myelin such as sheath length are thought to precisely tune conduction velocity ...
Manasi Iyer+12 more
doaj +4 more sources
A diffusion MRI model for random walks confined on cylindrical surfaces: towards non-invasive quantification of myelin sheath radius [PDF]
IntroductionQuantifying the myelin sheath radius of myelinated axons in vivo is important for understanding, diagnosing, and monitoring various neurological disorders.
Erick J. Canales-Rodríguez+13 more
doaj +3 more sources
Entangled biphoton generation in myelin sheath [PDF]
Consciousness within the brain hinges on the synchronized activities of millions of neurons, but the mechanism responsible for orchestrating such synchronization remains elusive. In this study, we employ cavity quantum electrodynamics (cQED) to explore entangled biphoton generation through cascade emission in the vibration spectrum of C-H bonds within ...
Zefei Liu, Yong-Cong Chen, Ping Ao
arxiv +6 more sources
Myelinating Schwann Cell Polarity and Mechanically-Driven Myelin Sheath Elongation [PDF]
Myelin sheath geometry, encompassing myelin sheath thickness relative to internodal length, is critical to optimize nerve conduction velocity and these parameters are carefully adjusted by the myelinating cells in mammals.
Nicolas Tricaud
doaj +6 more sources
Myelin sheath injury and repairment after subarachnoid hemorrhage [PDF]
Subarachnoid hemorrhage (SAH) can lead to damage to the myelin sheath in white matter. Through classification and analysis of relevant research results, the discussion in this paper provides a deeper understanding of the spatiotemporal change ...
Mao Chen+16 more
doaj +2 more sources
Identification of 3' UTR motifs required for mRNA localization to myelin sheaths in vivo.
Myelin is a specialized membrane produced by oligodendrocytes that insulates and supports axons. Oligodendrocytes extend numerous cellular processes, as projections of the plasma membrane, and simultaneously wrap multiple layers of myelin membrane around
Katie M Yergert+4 more
doaj +3 more sources
Clinical concentration of sevoflurane had no short-term effect on the myelin sheath in prefrontal cortex of aged marmosets [PDF]
IntroductionThe fragile brain includes both the developing brain in childhood and the deteriorating brain in elderly. While the effects of general anesthesia on the myelin sheath of developing brain have been well-documented, limited research has ...
Zhengjie Miao+6 more
doaj +2 more sources
A Jones matrix formalism for simulating three-dimensional polarized light imaging of brain tissue [PDF]
The neuroimaging technique three-dimensional polarized light imaging (3D-PLI) provides a high-resolution reconstruction of nerve fibres in human post-mortem brains. The orientations of the fibres are derived from birefringence measurements of histological brain sections assuming that the nerve fibres - consisting of an axon and a surrounding myelin ...
Amunts, Katrin+5 more
arxiv +7 more sources
Nanoscale correlated disorder in out-of-equilibrium myelin ultrastructure [PDF]
Ultrastructural fluctuations at nanoscale are fundamental to assess properties and functionalities of advanced out-of-equilibrium materials. We have taken myelin as a model of supramolecular assembly in out-of-equilibrium living matter. Myelin sheath is a simple stable multi-lamellar structure of high relevance and impact in biomedicine. Although it is
Bianconi, Antonio+6 more
arxiv +3 more sources
Shielding effects of myelin sheath on axolemma depolarization under transverse electric field stimulation [PDF]
Axonal stimulation with electric currents is an effective method for controlling neural activity. An electric field parallel to the axon is widely accepted as the predominant component in the activation of an axon.
Hui Ye, Jeffrey Ng
doaj +3 more sources