Results 1 to 10 of about 201,896 (346)

Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension [PDF]

Nature Communications
Myelin is essential for rapid nerve signaling and is increasingly found to play important roles in learning and in diverse diseases of the CNS. Morphological parameters of myelin such as sheath length are thought to precisely tune conduction velocity ...
Manasi Iyer, Husniye Kantarci, Madeline H. Cooper, Nicholas Ambiel, Sammy Weiser Novak, Leonardo R. Andrade, Mable Lam, Graham Jones, Alexandra E. Münch, Xinzhu Yu, Baljit S. Khakh, Uri Manor, J. Bradley Zuchero   +12 more
doaj   +5 more sources

Myelinating Schwann Cell Polarity and Mechanically-Driven Myelin Sheath Elongation [PDF]

Frontiers in Cellular Neuroscience, 2018
Myelin sheath geometry, encompassing myelin sheath thickness relative to internodal length, is critical to optimize nerve conduction velocity and these parameters are carefully adjusted by the myelinating cells in mammals.
Nicolas Tricaud
doaj   +7 more sources

Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo. [PDF]

Nat Neurosci, 2018
How action potentials regulate myelination by oligodendrocytes is uncertain. We show that neuronal activity raises [Ca2+]i in developing oligodendrocytes in vivo and that myelin sheath elongation is promoted by a high frequency of [Ca2+]i transients and ...
Krasnow AM, Ford MC, Valdivia LE, Wilson SW, Attwell D.   +4 more
europepmc   +4 more sources

A diffusion MRI model for random walks confined on cylindrical surfaces: towards non-invasive quantification of myelin sheath radius [PDF]

Frontiers in Physics
IntroductionQuantifying the myelin sheath radius of myelinated axons in vivo is important for understanding, diagnosing, and monitoring various neurological disorders.
Erick J. Canales-Rodríguez, Erick J. Canales-Rodríguez, Erick J. Canales-Rodríguez, Chantal M. W. Tax, Chantal M. W. Tax, Elda Fischi-Gomez, Elda Fischi-Gomez, Elda Fischi-Gomez, Derek K. Jones, Jean-Philippe Thiran, Jean-Philippe Thiran, Jean-Philippe Thiran, Jonathan Rafael-Patiño, Jonathan Rafael-Patiño   +13 more
doaj   +3 more sources

Entangled biphoton generation in myelin sheath [PDF]

Liu, Zefei, Yong-Cong Chen, and Ping Ao. "Entangled biphoton generation in the myelin sheath." Physical Review E 110.2 (2024): 024402
Consciousness within the brain hinges on the synchronized activities of millions of neurons, but the mechanism responsible for orchestrating such synchronization remains elusive. In this study, we employ cavity quantum electrodynamics (cQED) to explore entangled biphoton generation through cascade emission in the vibration spectrum of C-H bonds within ...
Zefei Liu, Yong-Cong Chen, Ping Ao
arxiv   +6 more sources

Dynamic properties of a reconstituted myelin sheath [PDF]

Spectroscopy, 2010
Myelin is a multilamellar membrane which, wrapping the nerve axons, increases the efficiency of nervous signal transmission. Indeed, the molecular components of the myelin sheath interact tightly with each other and molecules on the axonal surface to drive myelination, to keep both myelin and the axon intact, and to transduce signals from myelin to the
Knoll W, Natali F, Peters J, Nanekar R, Wang C, Kursula P   +5 more
semanticscholar   +7 more sources

Myelin sheath injury and repairment after subarachnoid hemorrhage [PDF]

Frontiers in Pharmacology, 2023
Subarachnoid hemorrhage (SAH) can lead to damage to the myelin sheath in white matter. Through classification and analysis of relevant research results, the discussion in this paper provides a deeper understanding of the spatiotemporal change ...
Mao Chen, Peiwen Guo, Peiwen Guo, Peiwen Guo, Xufang Ru, Xufang Ru, Xufang Ru, Yujie Chen, Yujie Chen, Yujie Chen, Shilun Zuo, Shilun Zuo, Shilun Zuo, Shilun Zuo, Hua Feng, Hua Feng, Hua Feng   +16 more
doaj   +2 more sources

Oligodendrocyte HCN2 Channels Regulate Myelin Sheath Length. [PDF]

J Neurosci, 2021
Oligodendrocytes generate myelin sheaths vital for the formation, health, and function of the CNS. Myelin sheath length is a key property that determines axonal conduction velocity and is known to be variable across the CNS.
Swire M, Assinck P, McNaughton PA, Lyons DA, Ffrench-Constant C, Livesey MR.   +5 more
europepmc   +2 more sources

The Akt-mTOR Pathway Drives Myelin Sheath Growth by Regulating Cap-Dependent Translation. [PDF]

J Neurosci, 2021
In the vertebrate CNS, oligodendrocytes produce myelin, a specialized membrane, to insulate and support axons. Individual oligodendrocytes wrap multiple axons with myelin sheaths of variable lengths and thicknesses.
Fedder-Semmes KN, Appel B.
europepmc   +2 more sources

Neurokeratin Network of Myelin Sheaths [PDF]

Nature, 1960
THE recent communication of Tewari and Bourne1 on the neurokeratin network of peripheral nerve fibres is valuable not only for its intrinsic content but also because it validates the histological procedures, findings and arguments derived therefrom, by which it was concluded that neurokeratin formations are part of the architecture of the nerve fibres ...
M. A. Macconaill, Edward Gurr
openaire   +3 more sources