Results 111 to 120 of about 48,603 (346)

On axoplasmic pressure waves and their possible role in nerve impulse propagation

open access: yes, 2010
It is suggested that the propagation of the action potential is accompanied by an axoplasmic pressure pulse propagating in the axoplasm along the axon length.
Rvachev, Marat M.
core   +1 more source

What's the Function of Connexin 32 in the Peripheral Nervous System? [PDF]

open access: yes, 2018
Connexin 32 (Cx32) is a fundamental protein in the peripheral nervous system (PNS) as its mutations cause the X-linked form of Charcot-Marie-Tooth disease (CMT1X), the second most common form of hereditary motor and sensory neuropathy and a demyelinating
Bortolozzi, Mario
core   +1 more source

Transplantation of Ciliary Neurotrophic Factor-Expressing Adult Oligodendrocyte Precursor Cells Promotes Remyelination and Functional Recovery after SpinalCord Injury [PDF]

open access: yes, 2010
Demyelination contributes to the dysfunction after traumatic spinal cord injury (SCI). We explored whether the combination of neurotrophic factors and transplantation of adult rat spinal cord oligodendrocyte precursor cells (OPCs) could enhance ...
Cao, Qilin   +11 more
core   +1 more source

Structurally and Functionally Adaptive Biomimetic Periosteum: Materials, Fabrication, and Construction Strategies

open access: yesExploration, EarlyView.
Schematic illustration of structural and functional biomimicry. The upper part shows BP with various structures such as monolayered, surface‐microstructural, bilayered and multilayered. The bottom part exhibits BP with different functions including immune regulation, drugs/cells/factors/ions loading, as well as bioelectrical stimulation and ...
Yuhan Du   +7 more
wiley   +1 more source

Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination [PDF]

open access: yes, 2017
Effective bidirectional signalling between axons and Schwann cells is essential for both the development and maintenance of peripheral nerve function. We have established conditions by which human induced pluripotent stem cell-derived sensory neurons can
Bennett, David L.H.   +5 more
core   +2 more sources

Dual‐Responsive Multi‐Functional Silica Nanoparticles With Repaired Mitochondrial Functions for Efficient Alleviation of Spinal Cord Injury

open access: yesExploration, EarlyView.
Targeting mitochondrial dysfunction presents a potential therapeutic approach for treating spinal cord injury. We have successfully designed and synthesized a functional Se@NADH nanodrug system. This system offers neuroprotective and neuroregenerative benefits by modulating mitochondrial function and neutralizing reactive oxygen species, thereby ...
Guibin Gao   +12 more
wiley   +1 more source

Temporal and partial inhibition of GLI1 in neural stem cells (NSCs) results in the early maturation of NSC derived oligodendrocytes in vitro. [PDF]

open access: yes, 2019
BackgroundOligodendrocytes are a type of glial cells that synthesize the myelin sheath around the axons and are critical for the nerve conduction in the CNS.
Biswas, Sangita   +5 more
core  

Probing white-matter microstructure with higher-order diffusion tensors and susceptibility tensor MRI. [PDF]

open access: yes, 2013
Diffusion MRI has become an invaluable tool for studying white matter microstructure and brain connectivity. The emergence of quantitative susceptibility mapping and susceptibility tensor imaging (STI) has provided another unique tool for assessing the ...
Li, Wei, Liu, Chunlei, Murphy, Nicole E
core   +1 more source

Dry Eye Disease: Oxidative Stress on Ocular Surface and Cutting‐Edge Antioxidants

open access: yesGlobal Challenges, EarlyView.
This review has systematically evaluated the oxidative damage of cornea, tear film, lacrimal gland, conjunctiva and meibomian gland for dry eye, and concluded the antioxidants that are either commercially available or in the research phase. GQDs: Graphene quantum dots; LF: lactoferrin; ROS: Reactive oxygen species; SOD: Superoxide dismutase; tFNA ...
Rong Hu   +3 more
wiley   +1 more source

Extent and mechanism of sealing in transected giant axons of squid and earthworms [PDF]

open access: yes, 1994
Transected axons are often assumed to seal at their cut ends by the formation of continuous membrane barriers that allow for the restoration of function in the axonal stumps.
Ballinger, Martis L.   +3 more
core   +1 more source

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