Results 141 to 150 of about 53,137 (327)

Oligodendrocyte Precursor Cells in Demyelination Repair: Mechanisms, Crosstalk, and Therapeutic Frontiers

Medicine Bulletin, EarlyView.
ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao, Mengdi Guo, Kehan Chen, Mei‐Ling Jiang, Lin‐ming Zhang, Lorenzo Di Cesare Mannelli, Cun‐jin Zhang   +6 more
wiley   +1 more source

Bioinformatics analysis of myelin-microbe interactions suggests multiple types of molecular mimicry in the pathogenesis of multiple sclerosis.

PLoS ONE
Multiple sclerosis (MS) is a devastating autoimmune disease that leads to the destruction of the myelin sheath in the human central nervous system (CNS).
Ali Bigdeli, Mostafa Ghaderi-Zefrehei, Bluma J Lesch, Mehrdad Behmanesh, S Shahriar Arab   +4 more
doaj   +1 more source

The Multiple Roles of Myelin Protein Genes During the Development of the Oligodendrocyte

ASN Neuro, 2009
It has become clear that the products of several of the earliest identified myelin protein genes perform functions that extend beyond the myelin sheath. Interestingly, these myelin proteins, which comprise proteolipid protein, 2′, 3′-cyclic nucleotide 3′-
Daniel Fulton, Pablo M Paez, Anthony T Campagnoni   +2 more
doaj   +1 more source

Functional Gap Junctions in the Schwann Cell Myelin Sheath [PDF]

, 1998
Rita J. Balice‐Gordon, Linda Jo Bone, Steven S. Scherer   +2 more
openalex   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

Medicinal Research Reviews, EarlyView.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh, Shubham Mahajan, Sadikalmahdi Abdella, Rehan Khan, Sanjay Garg   +4 more
wiley   +1 more source

Imaging the orientation of myelin sheaths in a non-stained histology slide of human brain [PDF]

, 2020
G. V. Schulz, Hans Deyhle, Christos Bikis, Oliver Bunk, Bert Müller   +4 more
openalex   +1 more source

Importance of R2 accuracy in susceptibility source separation

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose To examine the importance of R2 accuracy on independent paramagnetic and diamagnetic outputs from susceptibility source separation in the brain from two publicly available methods. Methods The effects of R2 errors, which translate into R2′$$ {\mathrm{R}}_2^{\prime } $$ errors, on output maps from χ‐separation and χ‐sepnet were examined
Tereza Beatriz Oliveira Assunção, Nashwan Naji, Jeff Snyder, Peter Seres, Gregg Blevins, Penelope Smyth, Alan H. Wilman   +6 more
wiley   +1 more source

P4–288: Influence of GETO extract on myelin sheath structure and myelin basic protein content in the brain with AD model [PDF]

, 2006
Jing Shi, Jinzhou Tian, Yi Xu, Junxiang Yin, Shuli Sheng, Yongyan Wang   +5 more
openalex   +1 more source

Docosahexaenoic acid ameliorates autistic‐like behaviors by inhibiting oxidative stress and inflammatory response in neonatal maternal separation rats

Pediatric Discovery, EarlyView.
The JNK pathway and oxidative stress are activated, and pro‐inflammatory cytokines are increased in neonatal maternal separation (NMS) rats. While docosahexaenoic acid treatment suppresses the activation of JNK pathway and oxidative stress, and reduces pro‐inflammatory cytokines release, thereby improving autism‐like behavior induced by NMS.
Boqing Xu, Hao Yuan, Xiaohuan Li, Qingyang Yu, Chunfang Dai, Zhifang Dong   +5 more
wiley   +1 more source

On axoplasmic pressure waves and their possible role in nerve impulse propagation

, 2010
It is suggested that the propagation of the action potential is accompanied by an axoplasmic pressure pulse propagating in the axoplasm along the axon length.
Rvachev, Marat M.
core   +1 more source