Results 21 to 30 of about 61,218 (243)
Data supporting the role of Fyn in initiating myelination in the peripheral nervous system
Data in Brief, 2016 Transgenic mice, which express active Fyn tyrosine kinase under the control of a glial fibrillary acidic protein promoter, have been produced. This promoter induces protein expression in the initiation stage of myelination in the peripheral nervous ...
Yuki Miyamoto +7 more
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Assessment of normal myelination in infants and young children using the T1w/T2w mapping technique
Frontiers in Neuroscience, 2023 BackgroundWhite matter myelination is a crucial process of CNS maturation. The purpose of this study was to validate the T1w/T2w mapping technique for brain myelination assessment in infants and young children.MethodsNinety-four patients (0–23 months of ...
Elena Filimonova +9 more
doaj +1 more source
Myelin lipid metabolism and its role in myelination and myelin maintenance
The Innovation, 2023 Myelin is a specialized cell membrane indispensable for rapid nerve conduction. The high abundance of membrane lipids is one of myelin's salient features that contribute to its unique role as an insulator that electrically isolates nerve fibers across their myelinated surface.
Joseph A. Barnes-Vélez +2 more
openaire +3 more sources
Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling
Data in Brief, 2017 Cytohesin-1 is the guanine-nucleotide exchange factor of Arf6, a small GTPase of Arf family, and participates in cellular morphological changes. Knockout mice of cytohesin-1 exhibit decreased myelination of neuronal axons in the peripheral nervous system
Ruri Tsuneishi +11 more
doaj +1 more source
Journal of Neuroscience Research, 2009 AbstractThe capacity to fold proteins properly is fundamental for cell survival. Secreted and transmembrane proteins are synthesized in the endoplasmic reticulum (ER), an organelle that has the ability to discriminate between native and nonnative proteins, in a process called protein quality control.
D'Antonio, Maurizio +2 more
openaire +2 more sources
Frontiers in Cellular Neuroscience, 2021 The benefits of transplanting cultured Schwann cells (SCs) for the treatment of spinal cord injury (SCI) have been systematically investigated in experimental animals since the early 1990s. Importantly, human SC (hSC) transplantation for SCI has advanced
Paula V. Monje +5 more
doaj +1 more source
Nature Communications, 2020 Myelination by Schwann cells (SC) in the peripheral nervous system is essential for motor function, and dysregulation of SC myelination can lead to various neuropathies.
Jincheng Wang +9 more
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Initiation of CNS Myelination in the Optic Nerve Is Dependent on Axon Caliber
Cell Reports, 2018 Summary: Emerging evidence suggests that neuronal signaling is important for oligodendrocyte myelination; however, the necessity of this signaling during development is unclear.
Sonia R. Mayoral +3 more
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Role of tumor necrosis factor-alpha in zebrafish retinal neurogenesis and myelination [PDF]
International Journal of Ophthalmology, 2016 AIM: To investigate the role of tumor necrosis factor-alpha (TNF-α) in zebrafish retinal development and myelination. METHODS: Morpholino oligonucleotides (MO), which are complementary to the translation start site of the wild-type embryonic zebrafish ...
Xu-Dan Lei +5 more
doaj +1 more source
Social Experience-Dependent Myelination: An Implication for Psychiatric Disorders
Neural Plasticity, 2015 Myelination is one of the strategies to promote the conduction velocity of axons in order to adjust to evolving environment in vertebrates. It has been shown that myelin formation depends on genetic programing and experience, including multiple factors ...
Michihiro Toritsuka +2 more
doaj +1 more source