Results 51 to 60 of about 43,839 (265)

Development and Optimization of Micro‐Nanotopographical Platforms for Surface Enhanced Raman Scattering Biomolecular Detection

open access: yesAdvanced Materials Interfaces, EarlyView.
Lithographically defined concentric micro‐ and nanostructures systematically designed and fabricated as reproducible arrays for Surface‐enhanced Raman spectroscopy applications. Abstract Topologically designed micro‐ and nanostructured surface‐enhanced Raman scattering (SERS) substrates propel the advancements of innovative applications, including ...
David Femi Odetade   +2 more
wiley   +1 more source

Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin‐expressing interneurons, and inhibitory function in the auditory cortex

open access: yesGlia, Volume 71, Issue 2, Page 187-204, February 2023., 2023
Main Point Loss of oligodendrocyte ErbB receptor signaling leads to A1 hypomyelination, reduced PV expression and density of PV+ neurons and synapses, hypoconnectivity of inhibitory circuits and shift of the E/I balance towards excitation. Abstract For a long time, myelin was thought to be restricted to excitatory neurons, and studies on dysmyelination
Beatriz C. Borges   +4 more
wiley   +1 more source

Restoration of axon conduction and motor deficits by therapeutic treatment with glatiramer acetate. [PDF]

open access: yes, 2014
Glatiramer acetate (GA; Copaxone) is an approved drug for the treatment of multiple sclerosis (MS). The underlying multifactorial anti-inflammatory, neuroprotective effect of GA is in the induction of reactive T cells that release immunomodulatory ...
Hayardeny, Liat   +6 more
core   +2 more sources

Multi‐Scale Modeling of a 3D Soft Magnetoelectric Patch for Wireless Nerve Stimulation

open access: yesAdvanced Materials Interfaces, EarlyView.
Core‐shell, magnetoelectric nanoparticles (MENPs) can serve as wireless electric nano‐sources, thanks to their ability to generate high levels of electricity, when stimulated by a human‐safe external magnetic field. By combining MENPs with soft, biocompatible polymeric matrices and optimizing its composite configuration and electrical behavior via ...
Giulia Suarato   +6 more
wiley   +1 more source

A subset of OPCs do not express Olig2 during development which can be increased in the adult by brain injuries and complex motor learning

open access: yesGlia, Volume 71, Issue 2, Page 415-430, February 2023., 2023
Main Points A subset of OPCs do not express Olig2, of which population peaks in the juvenile brain while wanes with age. Plastic changes of the brain by acute injuries or complex motor learning stop the expression of Olig2 in OPCs. Abstract Oligodendrocyte precursor cells (OPCs) are uniformly distributed in the mammalian brain; however, their function ...
Li‐Pao Fang   +7 more
wiley   +1 more source

In vivo functional and myeloarchitectonic mapping of human primary auditory areas [PDF]

open access: yes, 2012
In contrast to vision, where retinotopic mapping alone can define areal borders, primary auditory areas such as A1 are best delineated by combining in vivo tonotopic mapping with postmortem cyto- or myeloarchitectonics from the same individual.
Dick, Frederic   +5 more
core   +1 more source

Biological and Mechanical Limitations for Chronic Fast‐Scan Cyclic Voltammetry Sensor Design

open access: yesAdvanced Materials Technologies, EarlyView.
Real‐time detection of neurochemicals has demonstrated value in the field of neuroscience. However, current methods have limitations for use in the chronic setting, which is often the ideal environment for research. This article discusses these limitations, as well as technologies that have been developed to overcome them, and provides recommendations ...
Mason L. Perillo   +6 more
wiley   +1 more source

Galectin-3-mediated glial crosstalk drives oligodendrocyte differentiation and (Re)myelination [PDF]

open access: yes, 2018
Galectin-3 (Gal-3) is the only chimeric protein in the galectin family. Gal-3 structure comprises unusual tandem repeats of proline and glycine-rich short stretches bound to a carbohydrate-recognition domain (CRD).
Pasquini, Laura Andrea, Thomas, Laura
core   +1 more source

Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration

open access: yesAdvanced Therapeutics, EarlyView.
Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana   +5 more
wiley   +1 more source

Optical polarization evolution and transmission in multi-Ranvier-node axonal myelin-sheath waveguides [PDF]

open access: yesarXiv, 2023
In neuroscience, it is of interest to consider all possible modes of information transfer between neurons in order to fully understand processing in the brain. It has been suggested that photonic communication may be possible along axonal connections, especially through the myelin sheath as a waveguide, due to its high refractive index.
arxiv  

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