Comprehensive proteomic analysis of human cervical-vaginal fluid using colposcopy samples [PDF]
, 2009 Background Cervical-vaginal fluid (CVF) plays an important role in the prevention of gynecological infections, although little is known about the contribution of CVF proteins to the immunity of the lower female genital tract.
Tjalma Wiebren AA +4 more
core +2 more sources
KRAS mutation is associated with elevated myeloblastin activity in human lung adenocarcinoma.
Cancer genomics & proteomics, 2012 Lung cancer is the leading cause of all cancer deaths worldwide with suboptimal prognosis and treatment options. Therefore this study aimed to identify molecular characteristics with a predictive clinical utility which at the same time might represent novel therapeutic targets for human lung adenocarcinoma.
Wiedl, T +9 more
openaire +4 more sources
Regulationsmechanismen des Interferon regulatorischen Faktors IRF-4 in der chronisch myeloischen Leukämie [PDF]
, 2005 Zahlreiche Untersuchungen weisen darauf hin, dass die Gruppe der Interferon-regulatorischen Faktoren (IRF), darunter insbesondere ICSBP und IRF-4, in der Pathogenese der CML eine wichtige Rolle spielt.
Neubauer, Andreas (Prof. Dr.) +1 more
core +1 more source
ビタミンD受容体アゴニストとしての胆汁酸およびその誘導体：分子メカニズムと生物学的作用 [PDF]
, 2018 筑波大学University of Tsukuba博士（生物科学）Doctor of Philosophy in Biological ...
193574 +2 more
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A proteinase 3 contribution to juvenile idiopathic arthritis-associated cartilage damage [PDF]
, 2021 A full understanding of the molecular mechanisms implicated in the etiopathogenesis of juvenile idiopathic arthritis (JIA) is lacking. A critical role for leukocyte proteolytic activity (e.g., elastase and cathepsin G) has been proposed.
Berard, Roberta A. +5 more
core +2 more sources
From influenza infection to anti-ADAMTS13 autoantibodies via cross-reactivity [PDF]
, 2018 Autoantibodies (AAbs) against von Willebrand factor (vWF)-cleaving protease ADAMTS13 causally relate to thrombotic thrombocytopenic purpura (TTP). How anti-ADAMTS13 AAbs are generated is unknown.
Kanduc Darja
core +1 more source
Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients [PDF]
, 2020 Background: The aetiologies and pathogeneses of the joint diseases rheumatoid arthritis (RA) and spondyloarthritis (SpA) are still not fully elucidated.
Bennike, Tue Bjerg +8 more
core +1 more source
Different Faces for Different Places: Heterogeneity of Neutrophil Phenotype and Function
Journal of Immunology Research, Volume 2019, Issue 1, 2019., 2019 As the most abundant leukocytes in the circulation, neutrophils are committed to innate and adaptive immune effector function to protect the human body. They are capable of killing intruding microbes through various ways including phagocytosis, release of granules, and formation of extracellular traps.
Peiqing Yang +4 more
wiley +1 more source
Involvement of Kallikrein‐Related Peptidases in Normal and Pathologic Processes
Disease Markers, Volume 2015, Issue 1, 2015., 2015 Human kallikrein‐related peptidases (KLKs) are a subgroup of serine proteases that participate in proteolytic pathways and control protein levels in normal physiology as well as in several pathological conditions. Their complex network of stimulatory and inhibitory interactions may induce inflammatory and immune responses and contribute to the ...
Ana Carolina B. Stefanini +4 more
wiley +1 more source
Biomarcadores salivares no cancro da cabeça e pescoço [PDF]
, 2022 Head and neck cancer (HNC) are a group of cancers which occur in the organs from the anatomical area referred. The HNC staging system is generalized for most subtypes of HNC and restricted for the seven classifying stages of this cancer, which affects ...
Rentroia, Mara Ivone Santos
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