Results 11 to 20 of about 1,083 (144)
Modic type 2 changes are fibroinflammatory changes with complement system involvement adjacent to degenerated vertebral endplates [PDF]
JOR SPINE, Volume 6, Issue 1, March 2023., 2022 Background Vertebral endplate signal intensity changes visualized by magnetic resonance imaging termed Modic changes (MC) are highly prevalent in low back pain patients.
Aradi‐Vegh, Borbala +15 more
core +2 more sources
Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts. [PDF]
Chem BiodiversABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Antonysamy JMA +4 more
europepmc +2 more sources
Frontiers in Immunology, 2021 Sjögren’s Syndrome (SS) is an autoimmune exocrinopathy characterized by the progressive damage of salivary and lacrimal glands associated with lymphocytic infiltration.
Laís Garreto +14 more
doaj +1 more source
Adipose Tissue-Derived Small Extracellular Vesicles in Plasma Reveal Molecular Circuitries Underlying Glucose Intolerance. [PDF]
Obesity (Silver Spring)ABSTRACT Objective Glucose tolerance (GT) is a major effector for adipose tissue (AT) remodeling in obesity, yet its molecular mechanisms remain incompletely defined. We hypothesized that the biophysical and molecular profiles of AT‐derived small extracellular vesicles (sEVAT) change in response to glucose availability and differ by GT status.
Mishra S +10 more
europepmc +2 more sources
Non‐invasive diagnosis of early cutaneous squamous cell carcinoma
Experimental Dermatology, Volume 32, Issue 11, Page 1946-1959, November 2023., 2023 Abstract Early cutaneous squamous cell carcinoma (cSCC) can be challenging to diagnose using clinical criteria as it could present similar to actinic keratosis (AK) or Bowen's disease (BD), precursors of cSCC. Currently, histopathological assessment of an invasive biopsy is the gold standard for diagnosis.
Ali Azimi +3 more
wiley +1 more source
ESC Heart Failure, Volume 10, Issue 4, Page 2427-2437, August 2023., 2023 Abstract Aims Heart failure (HF) is a frequent condition in the elderly, further complicated by associated pulmonary hypertension (PH), with impact on morbidity and mortality. Plasma proteins associated with cardiovascular disease, related to inflammation, neurohormonal changes, and myocyte stress, pathways recognized in the pathophysiology of HF, may ...
Abdulla Ahmed +4 more
wiley +1 more source
The neutrophil: A key resourceful agent in immune‐mediated vasculitis
Immunological Reviews, Volume 314, Issue 1, Page 326-356, March 2023., 2023 Summary The term “vasculitis” refers to a group of rare immune‐mediated diseases characterized by the dysregulated immune system attacking blood vessels located in any organ of the body, including the skin, lungs, and kidneys. Vasculitides are classified according to the size of the vessel that is affected.
Karen Aymonnier +4 more
wiley +1 more source
PLoS ONE, 2020 COVID-19 or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appeared throughout the World and currently affected more than 9 million people and caused the death of around 470,000 patients.
Emel Akgun +8 more
doaj +1 more source
Potential Tear Biomarkers for the Diagnosis of Parkinson’s Disease—A Pilot Study [PDF]
, 2022 Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease. In this study, the tear proteome profile of patients with idiopathic PD (iPD, n = 24), carriers of the E46K-SNCA mutation (n = 3) and healthy control (
Acera Osa, Arantxa +9 more
core +1 more source
Rethinking the bile acid/gut microbiome axis in cancer [PDF]
, 2017 Dietary factors, probiotic agents, aging and antibiotics/medicines impact on gut microbiome composition leading to disturbances in localised microbial populations.
Caparros-Martin, Jose A. +4 more
core +1 more source