Results 21 to 30 of about 158,415 (307)

Landscape of Myeloid-derived Suppressor Cell in Tumor Immunotherapy

Biomarker Research, 2021
Myeloid-derived suppressor cells (MDSC) are a group of immature cells that produced by emergency myelopoiesis. Emerging evidences have identified the vital role of MDSC in cancer microenvironment, in which MDSC exerts both immunological and non ...
Zhaonian Hao, Ruyuan Li, Yuanyuan Wang, Shuangying Li, Zhenya Hong, Zhiqiang Han   +5 more
doaj   +1 more source

Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study [PDF]

, 2016
There is an increasing interest for monitoring circulating myeloid-derived suppressor cells (MDSCs) in cancer patients, but there are also divergences in their phenotypic definition.
Brandau, Sven, Britten, Cedrik M, Bronte, Vincenzo, Damuzzo, Vera, Gouttefangeas, C\ue9cile, Mandruzzato, Susanna, Maurer, Dominik, Ottensmeier, Christian, van der Burg, Sjoerd H, Walter, Steffen, Welters, Marij J. P   +10 more
core   +2 more sources

Myeloid derived suppressor cells and autoimmunity [PDF]

Human Immunology, 2016
Myeloid-derived suppressor cells are a heterogeneous group of immature myeloid cells with immunoregulatory function. When activated and expanded, these cells can suppress T cell functions via cell-to cell interactions as well as soluble mediators. Recent studies investigated the involvement of MDSC in autoimmune diseases.
Peter, Boros, Jordi, Ochando, Margit, Zeher   +2 more
openaire   +2 more sources

Staphylococcus aureus ATP Synthase Promotes Biofilm Persistence by Influencing Innate Immunity

mBio, 2020
Staphylococcus aureus is a major cause of prosthetic joint infection (PJI), which is characterized by biofilm formation. S. aureus biofilm skews the host immune response toward an anti-inflammatory profile by the increased recruitment of myeloid-derived ...
Megan E. Bosch, Blake P. Bertrand, Cortney E. Heim, Abdulelah A. Alqarzaee, Sujata S. Chaudhari, Amy L. Aldrich, Paul D. Fey, Vinai C. Thomas, Tammy Kielian   +8 more
doaj   +1 more source

Granulocytic myeloid-derived suppressor cells increased in early phases of primary HIV infection depending on TRAIL plasma level [PDF]

, 2017
Background It has been demonstrated that Myeloid Derived Suppressor Cells (MDSC) are expanded in HIV-1 infected individuals and correlated with disease progression.
Abbate, Isabella, Agrati, Chiara, Ammassari, Adriana, Antinori, Andrea, BILOTTA, MARIA TERESA, Bordoni, Veronica, CAPOBIANCHI, Maria Rosaria, Casetti, Rita, Cimini, Eleonora, Martini, Federico, Pinnetti, Carmela, Sacchi, Alessandra, Tumino, Nicola, Turchi, Federica   +13 more
core   +1 more source

Myeloid-Derived Suppressor Cells in Sepsis [PDF]

Frontiers in Immunology, 2019
Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells characterized by their immunosuppressive functions. MDSCs expand during chronic and acute inflammatory conditions, the best described being cancer. Recent studies uncovered an important role of MDSCs in the pathogenesis of infectious diseases along with sepsis.
Schrijver, Irene T., Théroude, Charlotte, Roger, Thierry   +2 more
openaire   +4 more sources

Myeloid-derived suppressor cells and their role in gynecological malignancies

Tumor Biology, 2018
Myeloid-derived suppressor cells are a heterogeneous population of immature myeloid cells that exhibit immunosuppressive activity (they block the proliferation and activity of both T cells and natural killer cells).
Seiji Mabuchi, Eriko Yokoi, Naoko Komura, Tadashi Kimura   +3 more
doaj   +1 more source

The downregulation of type I IFN signaling in G-MDSCs under tumor conditions promotes their development towards an immunosuppressive phenotype

Cell Death and Disease, 2022
Tumors modify myeloid cell differentiation and induce an immunosuppressive microenvironment. Granulocytic myeloid-derived suppressor cells (G-MDSCs), the main subgroup of myeloid-derived suppressor cells (MDSCs), are immature myeloid cells (IMCs) with ...
Yingying Sun, Xiaoqing Han, Chao Shang, Yawei Wang, Boya Xu, Shu Jiang, Yan Mo, Dake Wang, Yueshuang Ke, Xianlu Zeng   +9 more
doaj   +1 more source

Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells

iScience, 2021
Summary: Myeloid suppressor cells promote tumor growth by a variety of mechanisms which are not fully characterized. We identified myeloid cells (MCs) expressing the latency-associated peptide (LAP) of TGF-β on their surface and LAPHi MCs that stimulate ...
Galina Gabriely, Duanduan Ma, Shafiuddin Siddiqui, Linqing Sun, Nathaniel P. Skillin, Hadi Abou-El-Hassan, Thais G. Moreira, Dustin Donnelly, Andre P. da Cunha, Mai Fujiwara, Lena R. Walton, Amee Patel, Rajesh Krishnan, Stuart S. Levine, Brian C. Healy, Rafael M. Rezende, Gopal Murugaiyan, Howard L. Weiner   +17 more
doaj   +1 more source

Polyphenon E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells [PDF]

, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Note: In this manuscript as well as in the original published version of this article the word "Polyphenon" was incorrectly spelled in the title as ...
Adrian J. Thrasher, Arturo Sala, Chow, Croce, Dale, Daniel A. Morgenstern, Giorgia Santilli, Ikeda, Izabela Piotrowska, John Anderson, Katie Pearson, Marco D'Alicarnasso, Nourredine Himoudi, Olesya Chayka, Sandra Cantilena   +14 more
core   +2 more sources