Results 31 to 40 of about 7,249,751 (246)

Immunosuppressive effects and mechanisms of three myeloid-derived suppressor cells subsets including monocytic-myeloid-derived suppressor cells, granulocytic-myeloid-derived suppressor cells, and immature-myeloid-derived suppressor cells

Journal of Cancer Research and Therapeutics, 2021
Context: Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immune cells of myeloid lineage. Recent reports have suggested that human MDSC are divided into three subsets: monocytic MDSC (M-MDSC), granulocytic MDSC (G-MDSC), and immature MDSC (I-MDSC).
Yoshiaki, Nagatani, Yohei, Funakoshi, Hirotaka, Suto, Yoshinori, Imamura, Masanori, Toyoda, Naomi, Kiyota, Kimihiro, Yamashita, Hironobu, Minami   +7 more
openaire   +2 more sources

Polyphenon E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells [PDF]

, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Note: In this manuscript as well as in the original published version of this article the word "Polyphenon" was incorrectly spelled in the title as ...
Chayka, O, Sala, A, Piotrowska, I, Himoudi, N, D'Alicarnasso, M, Cantilena, S, Santilli, G, Morgenstern, DA, Thrasher, AJ, Pearson, K, Anderson, J   +10 more
core   +1 more source

Myeloid-Derived Suppressor Cells (MDSCs) in Haematology

, 2021
Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells with immunomodulating properties, mainly acting by suppressing T-cell responses [...
Nikoleta Bizymi, Helen A. Papadaki
core   +1 more source

Characteristics of “Tip-DCs and MDSCs” and their potential role in leishmaniasis [PDF]

, 2012
Since the first description of dendritic cells (DCs) by Steinman and Cohn (1973), the myeloid lineage of leukocytes was investigated intensively. Nowadays it is obvious that myeloid cells, especially DCs, are crucial for the adaptive and innate immune ...
Schmid, Maximilian, Anja Kathrin Wege, Maximilian eSchmid, Uwe eRitter, Anja K. Wege, Maximilian Schmid, Uwe Ritter, Ritter, Uwe, Wege, Anja K.   +8 more
core   +1 more source

Regulatory immune cells in transplantation. [PDF]

, 2012
Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control both the innate immune response triggered by the injured ...
Bushell, Andrew, Wood, Kathryn J, Andrew Bushell, Joanna Hester, Kathryn J. Wood, Hester, Joanna   +5 more
core   +1 more source

Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function [PDF]

, 2010
Acute-phase proteins (APPs) are an evolutionarily conserved family of proteins produced mainly in the liver in response to infection and inflammation.
Beraza, N., Linke, Reinhold P, Dierssen, U., Magarian Blander, J., Magarian Blander, Julie, Linke, R., Müller, M.R., Sander, Leif E., Leif E. Sander, Sander, L.E., Christian Trautwein, Dierssen, Uta, Trautwein, Christian, Sara Dutton Sackett, Sander, Leif Erik, Reinhold P. Linke, Müller, Michael, Tacke, F., Dutton Sackett, Sara, Tacke, Frank, Beraza, Naiara, Blander, J Magarian, Michael Müller, Uta Dierssen, Naiara Beraza, Frank Tacke, Sackett, S.D., Sackett, Sara Dutton, Blander, J.M., Trautwein, C., Sander, Leif E, J. Magarian Blander, Linke, Reinhold P.   +32 more
core   +1 more source

Myeloid-derived suppressor cells and their role in gynecological malignancies

Tumor Biology, 2018
Myeloid-derived suppressor cells are a heterogeneous population of immature myeloid cells that exhibit immunosuppressive activity (they block the proliferation and activity of both T cells and natural killer cells).
Seiji Mabuchi, Eriko Yokoi, Naoko Komura, Tadashi Kimura   +3 more
doaj   +1 more source

In Brief: Myeloid‐derived suppressor cells in cancer [PDF]

The Journal of Pathology, 2017
AbstractThe role of myeloid‐derived suppressor cells (MDSCs) in cancer development has become clear over recent years, and MDSC targeting is an emerging opportunity for enhancing the effectiveness of current anticancer therapies. As MDSCs are not only able to limit anti‐tumour T‐cell responses, but also to promote tumour angiogenesis and invasion ...
SOLITO, SAMANTHA, PINTON, LAURA, MANDRUZZATO, SUSANNA   +2 more
openaire   +2 more sources

Landscape of Myeloid-derived Suppressor Cell in Tumor Immunotherapy

Biomarker Research, 2021
Myeloid-derived suppressor cells (MDSC) are a group of immature cells that produced by emergency myelopoiesis. Emerging evidences have identified the vital role of MDSC in cancer microenvironment, in which MDSC exerts both immunological and non ...
Zhaonian Hao, Ruyuan Li, Yuanyuan Wang, Shuangying Li, Zhenya Hong, Zhiqiang Han   +5 more
doaj   +1 more source

On the origin of myeloid-derived suppressor cells

Oncotarget, 2016
Myeloid-derived suppressor cells (MDSCs) have a strong immunosuppressive character that allows them to regulate immune responses and hinder overt inflammatory responses. In cancer, this leads to tumor immune evasion and disease progression. MDSCs come in at least two forms: monocytic (Mo-MDSCs) and granulocytic (G-MDSCs).
Millrud, Camilla Rydberg, Bergenfelz, Caroline, Leandersson, Karin   +2 more
openaire   +3 more sources