Results 11 to 20 of about 107,803 (293)

Myocardial ischemia – reperfusion injury

Zaporožskij Medicinskij Žurnal, 2023
Aim. To summarize and broaden the idea about mechanisms of acute coronary insufficiency development and pathophysiological features of myocardial reperfusion injury.
S. V. Salo, V. O. Shumakov, S. S. Shpak, V. V. Tokhtarov   +3 more
doaj   +4 more sources

Myocardial Ischemia-Reperfusion/Injury [PDF]

Seminars in Cardiothoracic and Vascular Anesthesia, 2012
Myocardial ischemia reperfusion injury contributes to adverse cardiovascular outcomes after myocardial ischemia, cardiac surgery or circulatory arrest. Primarily, no blood flow to the heart causes an imbalance between oxygen demand and supply, named ischemia (from the Greek isch, restriction; and haema, blood), resulting in damage or dysfunction of ...
Saleh, Nermine, Youssef, Magda
openaire   +5 more sources

Platelets in Myocardial Ischemia/Reperfusion Injury

Hämostaseologie, 2022
AbstractCoronary artery disease, including myocardial infarction (MI), remains a leading cause of global mortality. Rapid reperfusion therapy is key to the improvement of patient outcome but contributes substantially to the final cardiac damage. This phenomenon is called “ischemia/reperfusion injury (IRI).” The underlying mechanisms of IRI are complex ...
Schanze, Nancy, Hamad, Muataz Ali, Nührenberg, Thomas G., Bode, Christoph, Dürschmied, Daniel Frank   +4 more
openaire   +3 more sources

Ubiquitin-specific protease 11 Aggravates Ischemia-reperfusion-induced Cardiomyocyte Pyroptosis and Injury by Promoting TRAF3 Deubiquitination

Balkan Medical Journal, 2023
Background: In myocardial ischemia-reperfusion injury, myocardial damage is aggravated when blood perfusion is restored in myocardial infarction. Ubiquitin-specific protease 11 (USP11), a deubiquitinating enzyme, could remove the ubiquitination of ...
Yunfei Zhang, Juledezi Hailati, Xiaoyun Ma, Hasidaer Midilibieke, Zhiqiang Liu   +4 more
doaj   +1 more source

Ilexsaponin A attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. [PDF]

PLoS ONE, 2017
The protective effects of ilexsaponin A on ischemia-reperfusion-induced myocardial injury were investigated. Myocardial ischemia/reperfusion model was established in male Sprague-Dawley rats. Myocardial injury was evaluated by TTC staining and myocardial
Shuang-Wei Zhang, Yu Liu, Fang Wang, Jiao Qiang, Pan Liu, Jun Zhang, Jin-Wen Xu   +6 more
doaj   +1 more source

Transient limb ischemia induces remote ischemic preconditioning in vivo [PDF]

, 2002
Background-Ischemic preconditioning reduces local tissue injury caused by subsequent ischemia-reperfusion (IR), but may also have a salutary effect on IR injury of tissues remote from those undergoing preconditioning.
Hoschtitzky, JA, Kharbanda, RK, Kristiansen, SB, MacAllister, R, Mortensen, UM, Redington, AN, Schmidt, MR, Sorensen, K, Vogel, M, White, PA   +9 more
core   +1 more source

Curcumin attenuates myocardial ischemia-reperfusion injury

Oncotarget, 2017
Cardiovascular diseases (CVDs) are at a badly high-risk of morbidity and mortality in the world.Our study was attempted to investigate the cardioprotective role of curcumin. Hearts injury was assessed in isolated hearts and the rats of coronary artery ligated.The inhibition of pro-inflammatory cytokines was observed by curcumin in coronary artery ...
Liu, Kun, Chen, Honglin, You, Qing-Sheng, Ye, Qing, Wang, Fei, Wang, Shuo, Zhang, Shuang-Long, Yu, Kang-Jun, Lu, Qi   +8 more
openaire   +3 more sources

The role of glycogen synthase kinase 3 beta in brain injury induced by myocardial ischemia/reperfusion injury in a rat model of diabetes mellitus

Neural Regeneration Research, 2017
Myocardial ischemia/reperfusion injury can lead to severe brain injury. Glycogen synthase kinase 3 beta is known to be involved in myo-cardial ischemia/reperfusion injury and diabetes mellitus. However, the precise role of glycogen synthase kinase 3 beta
Bo Zhao, Wen-wei Gao, Ya-jing Liu, Meng Jiang, Lian Liu, Quan Yuan, Jia-bao Hou, Zhong-yuan Xia   +7 more
doaj   +1 more source

Myocardial protective effect by ulinastatin via an anti-inflammatory response after regional ischemia/reperfusion injury in an in vivo rat heart model [PDF]

Korean Journal of Anesthesiology, 2011
BackgroundUlinastatin has anti-inflammatory properties and protects organs from ischemia/reperfusion-induced injury. The aim of this study was to investigate whether ulinastatin provides a protective effect on a regional myocardial ischemia/reperfusion ...
Il-Woo Shin, In-Seok Jang, Seung-Min Lee, Kyeong-Eon Park, Seong-Ho Ok, Ju-Tae Sohn, Heon-Keun Lee, Young-Kyun Chung   +7 more
doaj   +1 more source

Cardioprotective action of aprepitant in a rat model of ischemia-reperfusioninduced myocardial injury: role of PI3K-AkT-GSK-3β-HIF-1α signaling pathway

Acta Cirúrgica Brasileira, 2022
Purpose: The present study explored the role and mechanism involved in aprepitant-induced cardioprotective effects in rat model of ischemia-reperfusion injury.
Mei Qian, Yang Liu
doaj   +1 more source