ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]
, 1997 Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Becker, Bernhard F. +6 more
core +1 more source
The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]
, 2012 This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L +5 more
core +1 more source
Novel roles of κ-opioid receptor in myocardial ischemia-reperfusion injury [PDF]
PeerJAcute heart attack is the primary cause of cardiovascular-related death worldwide. A common treatment is reperfusion of ischemic tissue, which can cause irreversible damage to the myocardium.
Wen Zhang +4 more
doaj +2 more sources
The heartbreak of depression: 'Psycho-cardiac' coupling in myocardial infarction [PDF]
, 2017 Ample evidence identifies strong links between major depressive disorder (MDD) and both risk of ischemic or coronary heart disease (CHD) and resultant morbidity and mortality. The molecular mechanistic bases of these linkages are poorly defined. Systemic
Budiono, Boris P +5 more
core +1 more source
Frontiers in Pharmacology, 2021 Baicalin is a natural flavonoid glycoside that confers protection against myocardial ischemia/reperfusion (I/R) injury. However, its mechanism has not been fully understood.
Zhenyu Fan +4 more
doaj +1 more source
Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]
, 2017 Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto +10 more
core +2 more sources
Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice. [PDF]
PLoS ONE, 2014 Myocardial infarction resulting from ischemia-reperfusion injury can be reduced by cardiac postconditioning, in which blood flow is restored intermittently prior to full reperfusion.
Terrence Pong +4 more
doaj +1 more source
Platelet Contributions to Myocardial Ischemia/Reperfusion Injury [PDF]
Frontiers in Immunology, 2019 Obstruction of a coronary artery causes ischemia of heart tissue leading to myocardial infarction. Prolonged oxygen deficiency provokes tissue necrosis, which can result in heart failure and death of the patient. Therefore, restoration of coronary blood flow (reperfusion of the ischemic area) by re-canalizing the affected vessel is essential for a ...
Schanze, Nancy +2 more
openaire +4 more sources
Effects of propofol pretreatment on myocardial cell apoptosis and SERCA2 expression in rats with hepatic ischemia/reperfusion [PDF]
Revista Brasileira de Anestesiologia, 2018 Introduction: Hepatic ischemia-reperfusion injury is a common pathophysiological process in liver surgery. Whether Propofol can reduce myocardial ischemia-reperfusion injury induced by hepatic ischemia-reperfusion injury in rats, together with related ...
Shuzhen Yu +9 more
doaj +4 more sources
Long Noncoding RNAs in Myocardial Ischemia‐Reperfusion Injury
Oxidative Medicine and Cellular Longevity, 2021 Following an acute myocardial infarction, reperfusion therapy is currently the most effective way to save the ischemic myocardium; however, restoring blood flow may lead to a myocardial ischemia‐reperfusion injury (MIRI). Recent studies have confirmed that long‐chain noncoding RNAs (LncRNAs) play important roles in the pathophysiology of MIRIs.
Zhuo Zhao +5 more
openaire +2 more sources