Results 41 to 50 of about 107,803 (293)

Evolving Therapies for Myocardial Ischemia/Reperfusion Injury

Journal of the American College of Cardiology, 2015
The damage inflicted on the myocardium during acute myocardial infarction is the result of 2 processes: ischemia and subsequent reperfusion (ischemia/reperfusion injury). During the last 3 decades, therapies to reduce ischemic injury (mainly reperfusion strategies) have been widely incorporated into clinical practice.
Ibanez, B., Heusch, G., Ovize, Michel, Werf, F.   +3 more
openaire   +3 more sources

Post-TTM Rebound Pyrexia after Ischemia-Reperfusion Injury Results in Sterile Inflammation and Apoptosis in Cardiomyocytes [PDF]

, 2019
Introduction. Fever is frequently observed after acute ischemic events and is associated with poor outcome and higher mortality. Targeted temperature management (TTM) is recommended for neuroprotection in comatose cardiac arrest survivors, but pyrexia ...
Berger, Felix, Garlen, Nalina N. A. von, Krech, Jana, Lam, Phuong D., Schmitt, Katharina R. L., Tong, Giang, Wowro, Sylvia J.   +6 more
core   +1 more source

Modulation of Mitochondrial Bioenergetics in the Isolated Guinea Pig Beating Heart by Potassium and Lidocaine Cardioplegia: Implications for Cardioprotection [PDF]

, 2009
Mitochondria are damaged by cardiac ischemia/reperfusion (I/R) injury but can contribute to cardioprotection. We tested if hyperkalemic cardioplegia (CP) and lidocaine (LID) differently modulate mitochondrial (m) bioenergetics and protect hearts against ...
Aldakkak, Mohammed, Camara, Amadou K.S., Chen, Qun, Heisner, James S., Lesnefsky, Edward J., Stowe, David F.   +5 more
core   +2 more sources

Platelets, diabetes and myocardial ischemia/reperfusion injury

Cardiovascular Diabetology, 2017
Mechanisms underlying the pathogenesis of ischemia/reperfusion injury are particularly complex, multifactorial and highly interconnected. A complex and entangled interaction is also emerging between platelet function, antiplatelet drugs, coronary diseases and ischemia/reperfusion injury, especially in diabetic conditions.
RUSSO, Isabella, PENNA, Claudia, MUSSO, Tiziana, POPARA, JASMIN, ALLOATTI, Giuseppe, Cavalot, Franco, PAGLIARO, Pasquale   +6 more
openaire   +3 more sources

Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care [PDF]

, 2012
Author can archive publisher's pdf. Free via Creative Commons: CC-BENCHTOBEDSIDE-2.0.
Nandra, KK, Patel, NSA, Thiemermann, C
core   +1 more source

The Safety and Efficacy of Intravascular Lithotripsy in the Treatment of Severe Coronary Artery Calcification in 261 Cases: A Retrospective Study

Health Science Reports
Background Coronary artery calcification is strongly linked to factors such as advanced age, dyslipidemia, and chronic kidney disease. Severe coronary artery calcification significantly elevates the complexity and risk of percutaneous coronary ...
Tiankun Wu, Honghui Yang, Guian Xu, Qingman Li, Lijie Zhu, Yapan Yang, Tingjie Yang   +6 more
doaj   +1 more source

Myocardial ischemia reperfusion injury is alleviated by curcumin-peptide hydrogel via upregulating autophagy and protecting mitochondrial function

Stem Cell Research & Therapy, 2021
Background Ischemia-reperfusion injury (IRI) is an important factor limiting the success of cardiac reperfusion therapy. Curcumin has a significant cardioprotective effect against IRI, can inhibit ventricular remodeling induced by pressure load or MI ...
Chi-Lin Liao, Yang Liu, Meng-Zhao Huang, Hua-Yong Liu, Zi-Liang Ye, Qiang Su   +5 more
doaj   +1 more source

Endothelial preconditioning by transient oxidative stress reduces inflammatory responses of cultured endothelial cells to TNF-α [PDF]

, 2000
Brief episodes of ischemia can render an organ resistant to subsequent severe ischemia. This ‘ischemic preconditioning’ is ascribed to various mechanisms, including oxidative stress. We investigated whether preconditioning exists on an endothelial level.
Akimitsu T., BERNHARD F. BECKER, CHRISTIAN KUPATT, DeFily D. V., Hearse D. J., Hoshida S., Jerome S. N., Schreck R., Schulz R., Siegfried M. R., STEFAN ZAHLER, Yao Z.   +11 more
core   +1 more source

The temporal trends and short‐ and long‐term mortality of people with acute myocardial infarction and rheumatoid arthritis: a nationwide cohort study

Arthritis Care &Research, Accepted Article.
Aims We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analysed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalised with AMI between 2005 and 2019 from the MINAP registry, linked ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A Mamas   +8 more
wiley   +1 more source

Fructose 1,6-diphosphate alleviates myocardial ischemia reperfusion injury in rats through JAK2/STAT3 pathway

Asian Pacific Journal of Tropical Medicine, 2018
Objective: To study the effect of fructose 1,6-diphosphate (FDP) on myocardial ischemia reperfusion injury in rats and its molecular mechanism. Methods: Male SPF SD rats were selected as experimental animals and randomly divided into four groups.
Ju-Fei Wang, Cheng Jiang
doaj   +1 more source