Advances in separation and identification of biologically important milk proteins and peptides
ELECTROPHORESIS, Volume 45, Issue 1-2, Page 101-119, January 2024.Abstract Milk is a rich source of biologically important proteins and peptides. In addition, milk contains a variety of extracellular vesicles (EVs), including exosomes, that carry their own proteome cargo. EVs are essential for cell–cell communication and modulation of biological processes. They act as nature carriers of bioactive proteins/peptides in
Miroslava Stastna
wiley +1 more source
A mRNA landscape of bovine embryos after standard and MAPK-inhibited culture conditions: a comparative analysis. [PDF]
, 2015 BACKGROUND: Genes and signalling pathways involved in pluripotency have been studied extensively in mouse and human pre-implantation embryos and embryonic stem (ES) cells.
A Graf +95 more
core +2 more sources
HRB Open Research, 2018 Background: In Duchenne muscular dystrophy, primary abnormalities in the membrane cytoskeletal protein dystrophin trigger the loss of sarcolemmal linkage between the extracellular matrix component laminin-211 and the intracellular cortical actin membrane
Sandra Murphy +4 more
doaj +1 more source
Preferential, enhanced breast cancer cell migration on biomimetic electrospun nanofiber ‘cell highways’ [PDF]
, 2014 BACKGROUND: Aggressive metastatic breast cancer cells seemingly evade surgical resection and current therapies, leading to colonization in distant organs and tissues and poor patient prognosis.
Aaron Short +6 more
core +1 more source
Unraveling the molecular targets pertinent to junction restructuring events during spermatogenesis using the Adjudin-induced germ cell depletion model [PDF]
, 2007 During spermatogenesis, extensive restructuring takes place at the Sertoli-Sertoli and Sertoli-germ cell interface, which is regulated via intriguing interactions among cytokines, proteases, protease inhibitors, kinases, phosphatases, and transcription ...
Cheng, CY, Lee, WWM, Mruk, DD, Xia, W
core +1 more source
Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblasts [PDF]
, 2017 Cancer cells grow in highly complex stromal microenvironments, which through metabolic remodelling, catabolism, autophagy and inflammation nurture them and are able to facilitate metastasis and resistance to therapy.
Győrffy, Balázs +4 more
core
Characterization of FER1L5, a novel dysferlin myoferlin related protein [PDF]
, 2009 The ferlins are mammalian homologues of the C-elegans sperm vesicle fusion protein FER-1 characterised by multiple C2 domains and a C-terminal anchor.
Ramachandran, Usha Kalyani
core
Biology and enzymatic cleavage of ferlins: from membrane repair to cancer [PDF]
, 2018 Enzymatic cleavage can modify the function of target proteins. In this thesis I investigate the enzymatic cleavage of myoferlin and dysferlin, two members of the ferlin family.
Piper, Ann-Katrin
core
Myoferlin is a key regulator of EGFR activity in breast cancer. [PDF]
, 2013 peer reviewedMyoferlin is a member of the ferlin family of proteins that participate in plasma membrane fusion, repair and endocytosis. While some reports have implicated myoferlin in cancer, the extent of its expression in and contributions to cancer ...
Turtoi, Andrei +11 more
core +1 more source
Dysferlin mediates the cytoprotective effects of TRAF2 following myocardial ischemia reperfusion injury [PDF]
, 2014 BACKGROUND: We have demonstrated that tumor necrosis factor (TNF) receptor‐associated factor 2 (TRAF2), a scaffolding protein common to TNF receptors 1 and 2, confers cytoprotection in the heart.
Barger, Philip M +7 more
core +2 more sources