Results 101 to 110 of about 34,282 (300)
Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis
ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen +7 more
wiley +1 more source
Critical roles for multiple formins during cardiac myofibril development and repair
Molecular Biology of the Cell, 2014 Seven of 15 different mouse formins localized in diverse patterns to cardiomyocyte sarcomeres. Four were required for proper organization of myofibrils, and two were critical for remodeling and repair of myofibril structure.
M. Rosado +6 more
semanticscholar +1 more source
Experiment K-6-10. Effects of zero gravity on myofibril protein content and isomyosin distribution in rodent skeletal muscle [PDF]
The purpose of this experiment was to investigate the effects of 12 days of zero gravity (0G) exposure (Cosmos 1887 Biosputnik) on the enzymatic properties, protein content, and isomyosin distribution of the myofibril fraction of the slow-twitch vastus ...
Baldwin, K., Herrick, R., Oganov, V.
core +1 more source
Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers [PDF]
, 2015 Aims: Nebulette is a 109 kDa modular protein localized in the sarcomeric Z-line of the heart. In vitro studies have suggested a role of nebulette in stabilizing the thin filament, and missense mutations in the nebulette gene were recently shown to be ...
Bang, Marie-Louise +12 more
core +2 more sources
Food Biomacromolecules, EarlyView.Abstract The perception of flavor in a food system depends on its release from the protein matrix. Apart from hydrogen bonding, hydrophobic interactions and van der Waal's forces, the formation of covalent adducts between the flavor and protein highly impacts the release of flavor from the protein matrix.
Arshita Verma +2 more
wiley +1 more source
EMBO Reports, 2014 In Drosophila, fibrillar flight muscles (IFMs) enable flight, while tubular muscles mediate other body movements. Here, we use RNA‐sequencing and isoform‐specific reporters to show that spalt major (salm) determines fibrillar muscle physiology by ...
Maria L. Spletter +9 more
semanticscholar +1 more source
Nutrition in Clinical Practice, EarlyView.Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto +13 more
wiley +1 more source
Taxa de crescimento e fragmentação Miofibrilar diferenciadas em ratos submetidos a restrição alimentar e realimentação [PDF]
, 2008 Feed regimens alter muscle growth rate, hence they might impact the proteolytic system involved in tenderization during meat conditioning. The aim of this project was to verify the effects of feed restriction regimens on muscular and animal growth and ...
BAGALDO, Adriana Regina +4 more
core +3 more sources
Filamin protects myofibrils from contractile damage through changes in its mechanosensory region [PDF]
, 2023 Lucas A. B. Fisher +5 more
openalex +1 more source