The effect of recombinant caspase 3 on myofibrillar proteins in porcine skeletal muscle
Animal, 2008 The objective of this study was to investigate the potential role of the caspase protease family in meat tenderisation by examining if caspase 3 was capable of causing myofibril protein degradation.
C.M. Kemp, T. Parr
doaj +1 more source
Cells, 2020 The maintenance of skeletal muscle mass plays a critical role in health and quality of life. One of the most potent regulators of skeletal muscle mass is mechanical loading, and numerous studies have led to a reasonably clear understanding of the ...
Kent W. Jorgenson +2 more
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Inhibition of focal adhesion kinase increases myofibril viscosity in cardiac myocytes
Cytoskeleton, 2020 The coordinated generation of mechanical forces by cardiac myocytes is required for proper heart function. Myofibrils are the functional contractile units of force production within individual cardiac myocytes.
Nilay Taneja +5 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Displaced myofibrils termed ring fibers have been reported for human congenital myopathies and for myopathies of unknown etiology, but their natural cause largely remained elusive.
Lara-Jane Kepser +6 more
semanticscholar +1 more source
Modular proteins from the Drosophila sallimus (sls) gene and their expression in muscles with different extensibility [PDF]
, 2007 The passive elasticity of the sarcomere in striated muscle is determined by large modular proteins, such as titin in vertebrates. In insects, the function of titin is divided between two shorter proteins, projectin and sallimus (Sls), which are the ...
Ayme-Southgate +53 more
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Frontiers in Physiology, 2020 Skeletal muscle fibers are multinucleated cells that contain mostly myofibrils suspended in an aqueous media termed the sarcoplasm. Select evidence suggests sarcoplasmic hypertrophy, or a disproportionate expansion of the sarcoplasm relative to myofibril
Michael D. Roberts +6 more
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Thick filament‐associated myosin undergoes frequent replacement at the tip of the thick filament
FEBS Open Bio, 2022 Myosin plays a fundamental role in muscle contraction. Approximately 300 myosins form a bipolar thick filament, in which myosin is continuously replaced by protein turnover.
Emi Ichimura +4 more
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Tissue Tropism in Host Transcriptional Response to Members of the Bovine Respiratory Disease Complex. [PDF]
, 2017 Bovine respiratory disease (BRD) is the most common infectious disease of beef and dairy cattle and is characterized by a complex infectious etiology that includes a variety of viral and bacterial pathogens.
Behura, Susanta K +11 more
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Myofibril contraction and cross-linking drive nuclear movement to the periphery of skeletal muscle
Nature Cell Biology, 2017 Nuclear movements are important for multiple cellular functions, and are driven by polarized forces generated by motor proteins and the cytoskeleton. During skeletal myofibre formation or regeneration, nuclei move from the centre to the periphery of the ...
W. Roman +8 more
semanticscholar +1 more source
Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]
, 2014 Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
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