Results 91 to 100 of about 16,958 (213)

Transcriptomic comparative study between canalicular adenoma and HMGA2::WIF1 canalicular‐like pleomorphic adenoma

open access: yesThe Journal of Pathology, Volume 269, Issue 4-5, Page 423-432, August 2026.
Abstract Canalicular adenoma (CA) is a benign salivary gland tumor predominantly affecting the upper lip and is characterized by monomorphic epithelial cells arranged in branching cords within a loose and vascularized stroma. Unlike pleomorphic adenoma (PA), CA lacks a chondroid matrix and exhibits specific histological features, such as high cuboidal ...
Ziyad Alsugair   +8 more
wiley   +1 more source

Altered Skeletal Muscle Phosphate Metabolism After Muscle Damage Is Associated With Elevated Effort Perception During Exercise in Humans

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 8, August 2026.
ABSTRACT It remains unclear why exercising damaged muscles is perceived as disproportionately more effortful. Given the known role of inorganic phosphate (Pi) in fatigue and afferent sensory signaling, we tested whether muscle damage disrupts phosphate metabolism and whether this is associated with heightened ratings of perceived exertion (RPE ...
Jamie Stewart McPhee   +5 more
wiley   +1 more source

Phosphate and acidosis cause fibre type‐specific changes to cellular and molecular contractile mechanics at 37°C in skeletal muscle from older adults

open access: yesExperimental Physiology, Volume 111, Issue 8, Page 3753-3771, 1 August 2026.
Abstract Intracellular accumulation of hydrogen ions (H+) and inorganic phosphate (Pi) has temperature‐dependent effects on single‐fibre contractile function between 10°C and 30°C. In vivo, human skeletal muscle temperatures range between 35‐39°C, and although contractile function is highly dependent on temperature, the effects of fatigue‐inducing [H+]
Brent A. Momb   +3 more
wiley   +1 more source

Titin Is Present in the Elastic Tethers That Connect Separating Anaphase Chromosomes in Crane‐Fly Spermatocytes

open access: yesCytoskeleton, Volume 83, Issue 7, Page 496-514, July 2026.
ABSTRACT Elastic tethers connect telomeres of separating chromosomes in anaphase of animal cells. Immunofluorescence staining of titin in crane‐fly spermatocytes, using 4 different antibodies, shows that the giant elastic protein titin seems to be a component of mitotic tethers: titin “strands” extend between separating chromosomes, connecting their ...
Demetra Economopoulos   +5 more
wiley   +1 more source

Effect of Seaweed Fucoidan Incorporated Into Batter on Shelf Life Extension of Silver Carp (Hypophthalmichthys molitrix) Nugget During Refrigerated Storage

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
The fucoidan from Sargassum angustifolium incorporated directly in batter (0%, 1%, 2%, and 3% w/w; C, F1, F2, and F3, respectively) of silver carp (Hypophthalmichthys molitrix) nuggets increased some physiochemical properties during the refrigerated storage.
Sedigheh Babaei   +5 more
wiley   +1 more source

Heterozygous OGDH Variants Are Involved in Peripheral Neuropathy With Ataxia and Optical Atrophy

open access: yesJIMD Reports, Volume 67, Issue 4, July 2026.
ABSTRACT 2‐oxyglutarate dehydrogenase (OGDH) encodes an E1 component of α‐ketoglutarate dehydrogenase complex that plays a pivotal role in the Krebs cycle. Biallelic variants in OGDH have been reported to cause an early‐onset neurodevelopmental and mitochondrial disorder.
Liedewei Van de Vondel   +13 more
wiley   +1 more source

Prenatal Diagnosis and Functional Analysis of Two Compound Heterozygous Variants in the KLHL40 Gene Causing Nemaline Myopathy 8

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 7, July 2026.
This finding may broaden the pathogenic variant of c.1327G> A in the KLHL40 gene causing NEM8 and clarify the genotype and phenotype correlation. ABSTRACT Background Nemaline myopathy (NEM) is a rare congenital muscular disorder characterized by slow progression or static neuromuscular symptoms, which is mainly caused by variants in genes encoding the ...
Jianlong Zhuang   +4 more
wiley   +1 more source

An Integrative Methylation‐Metabolism Gene Signature Defines Prognosis and Immunosuppressive Microenvironment in Prostate Cancer

open access: yesChemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
This study developed a 6‐gene prognostic model integrating methylation and amino acid metabolism to predict PCa outcomes and reveal immunosuppressive TME. ABSTRACT The synergistic crosstalk between epigenetic dysregulation and metabolic reprogramming underlies to prostate cancer (PCa) development and treatment resistance, yet an integrated prognostic ...
Chao Zhang, Likun Liu, Kai Wu
wiley   +1 more source

Multi‐Omics Landscape of Paraspinal Muscles in Spinal Muscular Atrophy With Scoliosis

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Most spinal muscular atrophy (SMA) patients develop severe scoliosis by late adolescence. Given that the paraspinal muscles—particularly the multifidus—are indispensable for maintaining spinal stability, their site‐specific multi‐omics characteristics in SMA remain insufficiently defined. Herein, integrated multi‐omics sequencing was performed
Zhen Wang   +4 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

open access: yesPhotochemistry and Photobiology, Volume 102, Issue 4, Page 797-831, July/August 2026.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew   +3 more
wiley   +1 more source

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