Results 81 to 90 of about 31,768 (245)

ULTRASTRUCTURAL FEATURES OF CARDIOMYOCYTE CONTRACTILE APPARATUS IN RAT OFFSPRING HEARTS FOLLOWING MATERNAL CHRONIC ALCOHOL INTOXICATION

Проблеми екології та медицини
Background. The mechanisms underlying the development of the heart contractile apparatus and the distribution of myofibrils in cardiomyocytes following intrauterine ethanol intoxication continue to be a topic of significant debate.
I.V. Tverdokhlib, D.G. Marchenko
doaj   +1 more source

Altered excitation-contraction coupling in human chronic atrial fibrillation [PDF]

, 2012
This review focuses on the (mal)adaptive processes in atrial excitation-contraction coupling occurring in patients with chronic atrial fibrillation. Cellular remodeling includes shortening of the atrial action potential duration and effective refractory ...
Grandi, E., Pandit, S.V., Workman, A.J.
core   +1 more source

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan, Meryem İlkay Karagül, Hatice Oruç Demirbağ, Ebru Balli   +3 more
wiley   +1 more source

Polarization-resolved microscopy reveals a muscle myosin motor-independent mechanism of molecular actin ordering during sarcomere maturation.

PLoS Biology, 2018
Sarcomeres are stereotyped force-producing mini-machines of striated muscles. Each sarcomere contains a pseudocrystalline order of bipolar actin and myosin filaments, which are linked by titin filaments.
Olivier Loison, Manuela Weitkunat, Aynur Kaya-Çopur, Camila Nascimento Alves, Till Matzat, Maria L Spletter, Stefan Luschnig, Sophie Brasselet, Pierre-François Lenne, Frank Schnorrer   +9 more
doaj   +1 more source

Specific Staining of Muscle Cytoskeletal Proteins in Litopenaeus vannamei and Their Role in Textural Deterioration during Refrigeration [PDF]

Shipin Kexue
To clarify the key material basis for the rapid softening of shrimp muscle during refrigeration, this study established a specific histological detection method for cytoskeletal proteins and analyzed the correlation between the degradation of ...
CAI Peifeng, LIAO Weilong, FENG Jun, HU Li, LI Caihong, XU Defeng
doaj   +1 more source

Bronchial Mucosal Abnormalities in Idiopathic Subglottic Stenosis

The Laryngoscope, EarlyView.
Idiopathic subglottic stenosis (iSGS) is a challenging variant of airway stenosis associated with consistent distal airway abnormalities on bronchoscopy, including pits, depressions, and striations. Despite these findings, most patients demonstrate normal or mild–moderate obstruction on spirometry.
Sydney Ring, Andrew Jay Bowen, Tessa Griffin, J. Scott Ferguson, Seth H. Dailey   +4 more
wiley   +1 more source

Effects of Protein Kinase A on the Phosphorylation Status and Transverse Stiffness of Cardiac Myofibrils

Journal of Pharmacological Sciences, 2013
Stimulation of β-adrenergic receptors in cardiac myocytes activates cyclic AMP– dependent protein kinase A (PKA). PKA-mediated phosphorylation of myofibrils decreases their longitudinal stiffness, but its effect on transverse stiffness is not fully ...
Yoshiki Ohnuki, Takenori Yamada, Yasumasa Mototani, Daisuke Umeki, Kouichi Shiozawa, Takayuki Fujita, Yasutake Saeki, Satoshi Okumura   +7 more
doaj   +1 more source

Association between serum bicarbonate and low mid‐upper arm circumference in patients with non‐dialysis‐dependent chronic kidney disease: A cross‐sectional study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto, Shintaro Mandai, Tamami Fujiki, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Shotaro Naito, Eisei Sohara, Tatsuhiko Anzai, Kunihiko Takahashi, Wataru Akita, Akihito Ohta, Shinichi Uchida, Soichiro Iimori   +13 more
wiley   +1 more source

A novel imaging method (FIM-ID) reveals that myofibrillogenesis plays a major role in the mechanically induced growth of skeletal muscle

eLife
An increase in mechanical loading, such as that which occurs during resistance exercise, induces radial growth of muscle fibers (i.e. an increase in cross-sectional area).
Kent W Jorgenson, Jamie E Hibbert, Ramy KA Sayed, Anthony N Lange, Joshua S Godwin, Paulo HC Mesquita, Bradley A Ruple, Mason C McIntosh, Andreas N Kavazis, Michael D Roberts, Troy A Hornberger   +10 more
doaj   +1 more source

Transcriptomic comparative study between canalicular adenoma and HMGA2::WIF1 canalicular‐like pleomorphic adenoma

The Journal of Pathology, EarlyView.
Abstract Canalicular adenoma (CA) is a benign salivary gland tumor predominantly affecting the upper lip and is characterized by monomorphic epithelial cells arranged in branching cords within a loose and vascularized stroma. Unlike pleomorphic adenoma (PA), CA lacks a chondroid matrix and exhibits specific histological features, such as high cuboidal ...
Ziyad Alsugair, Anne Champagnac, Maxime Fieux, Pierre Philouze, Philippe Ceruse, Brice Thamphya, Daniel Pissaloux, Franck Tirode, Nazim Benzerdjeb   +8 more
wiley   +1 more source