Results 81 to 90 of about 16,958 (213)

Nanostructural organization of skeletal muscle myocytes revealed by scanning probe nanotomography

Вестник трансплантологии и искусственных органов
Objective: to perform a statistical analysis of the angular orientations of hexagonal myofilament lattices in rat skeletal muscle myofibrils using scanning probe nanotomography (SPN). Materials and methods.
A. E. Efimov, T. K. Milenin, E. I. Podbolotova, N. V. Grudinin, O. I. Agapova, I. I. Agapov   +5 more
doaj   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct Sarcomeric Protein Isoforms

Frontiers in Physiology, 2018
Characterizing the contractile function of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) is key for advancing their utility for cellular disease models, promoting cell based heart repair, or developing novel pharmacological interventions ...
Bogdan Iorga, Bogdan Iorga, Kristin Schwanke, Natalie Weber, Meike Wendland, Stephan Greten, Birgit Piep, Cristobal G. dos Remedios, Ulrich Martin, Robert Zweigerdt, Theresia Kraft, Bernhard Brenner   +11 more
doaj   +1 more source

Polymorphic myopathological findings in a 77‐year‐old woman with oculo‐bulbo‐facial and distal weakness

Brain Pathology, EarlyView.
Michele Tosi, Angela Puma, Elena Faedo, Gianmarco Severa, Luisa Villa, Sabrina Sacconi, Edoardo Malfatti   +6 more
wiley   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

Effect of Sarcoplasmic Protein Solutions Dried at Different Times and Rates on Water Migration in Lamb Myofibril In Vitro

Foods
To determine whether sarcoplasmic proteins affected water migration in myofibrils during air-drying, with protein denaturation as an indicator of sarcoplasmic protein changes, the extent of sarcoplasmic protein changes in lamb during air-drying was first
Weili Rao, Sijia Liu, Shiquan Kong, Zhenyu Wang, Zidan Shi, Jianming Cai   +5 more
doaj   +1 more source

Sustained Release and Therapeutic Evaluation of Simvastatin‐Loaded Bioglass–Chitosan Gel Formulation for Skin Regeneration and Wound Healing Potential

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
A multifunctional chitosan–gallic acid hydrogel incorporated with heparin modified Zn–Ag doped bioglass and simvastatin was synthesized for chronic wound healing. The system shows antioxidant, antimicrobial, and pro‐angiogenic properties, promoting cell proliferation and collagen production.
Durgesh Kumar, Suhela Tyeb, Baby Shruit Shukla, Vivek Verma, Nitesh Kumar   +4 more
wiley   +1 more source

Unveiling New Insights: Reinterpreting DES Mutation, p.Arg383His, Through a Study of an Iranian Family With Isolated Hypertrophic Cardiomyopathy, Implication for Phenotype–Genotype Correlation Analysis

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Desmin, a crucial intermediate filament in muscle cells, maintains structural integrity in cardiac muscle and provides stability to striated muscle cells. Mutations in the DES gene lead to desminopathies, causing diverse cardiac and skeletal myopathies.
Saeideh Kavousi, Farzad Kamali, Bahareh Rabbani, Mehrdad Behmanesh, Nejat Mahdieh, Mehrdad Noruzinia   +5 more
wiley   +1 more source

The Impact of Ageing on Skeletal Muscle: Roles of Mitochondrial Dysregulation, Systemic Communication, and Exercise

Journal of Cellular Physiology, Volume 241, Issue 8, August 2026.
ABSTRACT Ageing is a major risk factor for degenerative diseases, including sarcopenia, which is characterized by a progressive loss of skeletal muscle mass and function, frailty, and is associated with increased mortality. Skeletal muscle regeneration relies on muscle stem cells and efficient communication with cellular microenvironment.
Juan Diego Hernández‐Camacho, Marielle Saclier   +1 more
wiley   +1 more source

Bronchial Mucosal Abnormalities in Idiopathic Subglottic Stenosis

The Laryngoscope, Volume 136, Issue 8, Page 3527-3533, August 2026.
Idiopathic subglottic stenosis (iSGS) is a challenging variant of airway stenosis associated with consistent distal airway abnormalities on bronchoscopy, including pits, depressions, and striations. Despite these findings, most patients demonstrate normal or mild–moderate obstruction on spirometry.
Sydney Ring, Andrew Jay Bowen, Tessa Griffin, J. Scott Ferguson, Seth H. Dailey   +4 more
wiley   +1 more source