Results 121 to 130 of about 32,619 (226)

Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy

Developmental Medicine &Child Neurology, Volume 68, Issue 3, Page 343-357, March 2026.
Cerebral palsy, caused by non‐progressive brain injury, is frequently accompanied by skeletal muscle alterations. This review synthesizes current evidence from muscle biopsy studies, revealing cellular and molecular adaptations in muscle tissue. Abstract Cerebral palsy (CP), the most prevalent childhood‐onset motor disability, frequently entails ...
Sebastian Edman, Oscar Horwath, Eva Pontén, Sudarshan Dayanidhi, Ferdinand von Walden   +4 more
wiley   +1 more source

Effect of Sarcoplasmic Protein Solutions Dried at Different Times and Rates on Water Migration in Lamb Myofibril In Vitro

Foods
To determine whether sarcoplasmic proteins affected water migration in myofibrils during air-drying, with protein denaturation as an indicator of sarcoplasmic protein changes, the extent of sarcoplasmic protein changes in lamb during air-drying was first
Weili Rao, Sijia Liu, Shiquan Kong, Zhenyu Wang, Zidan Shi, Jianming Cai   +5 more
doaj   +1 more source

Mammalian formin Fhod3 plays an essential role in cardiogenesis by organizing myofibrillogenesis

Biology Open, 2012
Summary Heart development requires organized integration of actin filaments into the sarcomere, the contractile unit of myofibrils, although it remains largely unknown how actin filaments are assembled during myofibrillogenesis.
Meikun Kan-O, Ryu Takeya, Takaya Abe, Naoyuki Kitajima, Motohiro Nishida, Ryuji Tominaga, Hitoshi Kurose, Hideki Sumimoto   +7 more
doaj   +1 more source

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

Animal Research and One Health, Volume 4, Issue 1, Page 36-54, February 2026.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li, Yanyan Sun, Jingwei Yuan, Xiangchen Li, Lei Shi, Adamu Mani Isa, Yuanmei Wang, Pingzhuang Ge, Yunhe Zong, Panlin Wang, Jilan Chen   +10 more
wiley   +1 more source

Fibre Type–Specific Proteomics Reveals Shared and Distinct Skeletal Muscle Adaptations to Resistance Training and Beta2‐Adrenergic Agonist

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Skeletal muscle is essential for metabolic health and physical function. While resistance training promotes muscle hypertrophy, alternative therapeutic strategies are needed for individuals unable to engage in physical activity. Because beta2‐adrenergic stimulation induces muscle growth without mechanical load, we assessed muscle ...
Søren Jessen, Andrea Di Credico, Roger Moreno‐Justicia, Lukas Moesgaard, Anders Lemminger, Ben Stocks, Angela Di Baldassarre, Jens Bangsbo, Atul S. Deshmukh, Morten Hostrup   +9 more
wiley   +1 more source

Reference Methods for Measuring Skeletal Muscle Mass: A Critical Perspective

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Skeletal muscle (SM) is an integral organ component in the pathophysiology of many acute and chronic diseases. But is there a ‘gold’ standard or accepted reference method for quantifying the amount and composition of human SM mass? Exploring that question led us to recognize the existence of a SM measurement paradigm that divides methods into ...
Steven B. Heymsfield, Houchun H. Hu, Edvin Johanssen, Sophia Ramirez, Gabriela de Oliveira Lemos, Maria Cristina Gonzalez, Carla M. Prado, Jonathan P. Bennett   +7 more
wiley   +1 more source

Single‐Nucleus Transcriptome Reveals Cellular Heterogeneity and Transcriptional Response to Heat Stress in Skeletal Muscle

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Heat stress can induce skeletal muscle injury. Typical characteristics of heat‐exposed muscle tissues include apoptosis, oxidative stress and autophagy. The understanding of molecular mechanisms underlying heat stress‐induced muscle injury is limited, especially at the single‐cell transcription level.
Ziyin Han, Li Chen, Zhiyu Lei, Jiaman Zhang, Ziyu Chen, Xiaolan Fan, Bo Zeng, Anan Jiang, Hai Xiang, Hua Li, Mingzhou Li, Long Jin   +11 more
wiley   +1 more source

Largely Distinct Post‐Translational Modifications Differentiate Skeletal Muscle Wasting Caused by Cancer, Dexamethasone and Aging

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Skeletal muscle wasting and weakness are prominent disease features. Originally considered to arise from common transcriptional changes, recent analyses demonstrated that different stimuli induce muscle wasting via largely distinct mRNA and protein changes.
Anna Stephan, Flavia A. Graca, Suresh Poudel, Yingxue Fu, Yong‐Dong Wang, Myriam Labelle, Fabio Demontis   +6 more
wiley   +1 more source

Thymoquinone Protects Against Cardiac Hypertrophy via PPAR‐γ/PI3K/Akt Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Thymoquinone (TQ), the principal active constituent of Nigella stativa, has demonstrated numerous biological properties and therapeutic effects on various diseases. However, its therapeutic potential against cardiac hypertrophy remains uncertain.
Rong‐bin Qiu, Zi‐ming Wu, Zhi‐qiang Xu, Li‐juan Hu, Shi‐tao Zhao, Rui‐yuan Zeng, Zhi‐cong Qiu, Lian‐fen Zhou, Song‐qing Lai, Wen‐jun Wang, Li Wan   +10 more
wiley   +1 more source

Integrating Transcriptomics and Gut Microbiota Analysis Reveals the Anti‐Osteoporotic Mechanisms of Wine and Oil Co‐Processed Epimedium

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Firstly, we determined the content of the components in the co‐products of Epimedium wine and oil. Secondly, the clinical indications of the co‐products of Epimedium wine and oil were determined by in vitro cell experiments. Finally, the in vivo animal model was used for experimental verification.
Jinling Liang, Shichang Li, Yulin Dai, Zifeng Pi, Jia Liu, Pan Li, Weixia Sun, Tao Jiang, Tianyang Xu, Peng Yu   +9 more
wiley   +1 more source