Results 171 to 180 of about 1,662 (193)
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Cell cycle exit upon myogenic differentiation
Current Opinion in Genetics & Development, 1997Myogenic precursor cells withdraw irreversibly from the cell cycle as they differentiate into mature myotubes. Cell cycle exit occurs early during the differentiation program and is required for normal expression of the contractile phenotype. Differentiated myocytes also display a decreased propensity to undergo apoptotic cell death.
K, Walsh, H, Perlman
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Role of JAK3 in myogenic differentiation
Cellular Signalling, 2012Skeletal muscle differentiation is regulated by transcription factors, including members of the myogenic regulatory factor (MRF) family and many signaling pathways. The JAK1 and JAK2 pathways are known to each have different effects on myoblast proliferation and differentiation; however, the role of JAK3 in myoblast differentiation remains unclear.
You-Na, Jang +3 more
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Control of Myogenic Differentiation by Cellular Oncogenes
Molecular Neurobiology, 1988The establishment of a differentiated phenotype in skeletal muscle cells requires withdrawal from the cell cycle and termination of DNA synthesis. Myogenesis can be inhibited by serum components, purified mitogens, and transforming growth factors, but the intracellular signaling pathways utilized by these molecules are unknown.
M D, Schneider, E N, Olson
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Effects of growth factors on myogenic differentiation
American Journal of Physiology-Cell Physiology, 1989It has now been well established that the terminal differentiation of muscle cells in culture is subject to control by hormones and growth factors in the incubation medium. Thus far the most potent and most extensively studied agents are fibroblast growth factor (FGF), the insulinlike growth factors (IGFs), and transforming growth factor-beta (TGF ...
J R, Florini, K A, Magri
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Myogenic Differentiation by Human Processed Lipoaspirate Cells
Plastic and Reconstructive Surgery, 2002The use of undifferentiated cells for cell-based tissue engineering and regeneration strategies represents a promising approach for skeletal muscle repair. For such strategies to succeed, a readily available source of myogenic precursor cells must be identified. We have previously shown that cells isolated from raw human lipoaspirates, called processed
Hiroshi, Mizuno +5 more
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Cutaneous mesenchymal hamartoma with mixed myogenous differentiation
Journal of Cutaneous Pathology, 2006Abstract:A 3‐month‐old infant girl presented with a polypoid lesion in the perianal region. No changes in this lesion had been noted since birth. Microscopic examination of the excised specimen showed a mixture of mesenchymal elements, dominated by haphazard thin fascicles of skeletal muscle.
John Edwin, Schrecengost +3 more
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Involvement of Hexose transport in myogenic differentiation
Journal of Cellular Physiology, 1990AbstractA high (HAHT) and a low (LAHT) affinity hexose transport system are present in undifferentiated rat L6 myoblasts; however, only the latter can be detected in multinucleated myotubes. This suggests that HAHT is either down‐regulated or modified as a result of myogenesis.
P A, Kudo, T C, Lo
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Jun inhibits myogenic differentiation.
Oncogene, 1991Myoblasts from skeletal muscle of chicken or Japanese quail embryos were infected with avian sarcoma virus 17 (ASV-17), a retrovirus carrying the jun oncogene. At high multiplicities of infection ASV-17-induced morphologic transformation inhibited fusion of myoblasts into myotubes and stimulated extended replication.
H Y, Su +3 more
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Myostatin is an inhibitor of myogenic differentiation
American Journal of Physiology-Cell Physiology, 2002Myostatin (MSTN), a transforming growth factor (TGF)-β superfamily member, has been shown to negatively regulate muscle growth by inhibiting muscle precursor cell proliferation. Here, we stably transfected C2C12 cells with mouse MSTN cDNA to investigate its possible role in myoblast differentiation.
Ramón, Ríos +3 more
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Cutaneous extrarenal rhabdoid tumor with myogenic differentiation
Journal of Cutaneous Pathology, 2005Background: The rhabdoid phenotype is characterized by large epithelioid cells with abundant eosinophilic cytoplasm and paranuclear inclusions of intermediate filaments. Although originally described in tumors from pediatric kidneys, the rhabdoid phenotype has since been described in a variety of patient ages and extrarenal sites. Extraordinarily, the
Matthew, Petitt +3 more
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