Neuromuscular electrical stimulation alleviates stroke-related sarcopenia by promoting satellite cells myogenic differentiation via AMPK-ULK1-Autophagy axis. [PDF]
Xiang X +14 more
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Possible involvement of zinc transporter ZIP13 in myogenic differentiation. [PDF]
Shoji M +17 more
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Ythdf2 facilitates precursor miR-378/miR-378-5p maturation to support myogenic differentiation. [PDF]
Deng K +8 more
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Inhibition of Sesn2 has negative regulatory effects on the myogenic differentiation of C2C12 myoblasts. [PDF]
Song Z, Lin Q, Liang J, Zhang W.
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Exogenous hydrogen sulfide enhances myogenic differentiation of C2C12 myoblasts under high palmitate stress. [PDF]
Lu F +12 more
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LncRNA 4930581F22Rik promotes myogenic differentiation by regulating the ERK/MAPK signaling pathway. [PDF]
Chen WC +12 more
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Immunofluorescence analysis of myogenic differentiation
2022Skeletal muscle is a highly regenerative tissue that can efficiently recover from various damages caused by injuries and excessive exercises. In adult muscle, stem cells termed satellite cells are mitotically quiescent but activated upon muscle damages to enter the cell cycle as myogenic precursor cells or myoblasts. After several rounds of cell cycles,
Atsushi, Asakura, Nobuaki, Kikyo
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Hormones, Growth Factors, and Myogenic Differentiation
Annual Review of Physiology, 1991Three families of growth factors/hormones have major effects on the differentiation of skeletal muscle cells. Two (FGF and TGF-beta) are potent inhibitors, and the third (IGF) exhibits a biphasic stimulatory action (but is not inhibitory even at high concentrations).
J R, Florini, D Z, Ewton, K A, Magri
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Cell cycle exit upon myogenic differentiation
Current Opinion in Genetics & Development, 1997Myogenic precursor cells withdraw irreversibly from the cell cycle as they differentiate into mature myotubes. Cell cycle exit occurs early during the differentiation program and is required for normal expression of the contractile phenotype. Differentiated myocytes also display a decreased propensity to undergo apoptotic cell death.
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Role of JAK3 in myogenic differentiation
Cellular Signalling, 2012Skeletal muscle differentiation is regulated by transcription factors, including members of the myogenic regulatory factor (MRF) family and many signaling pathways. The JAK1 and JAK2 pathways are known to each have different effects on myoblast proliferation and differentiation; however, the role of JAK3 in myoblast differentiation remains unclear.
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