Results 251 to 260 of about 64,746 (288)

Control of Myogenic Differentiation by Cellular Oncogenes

Molecular Neurobiology, 1988
The establishment of a differentiated phenotype in skeletal muscle cells requires withdrawal from the cell cycle and termination of DNA synthesis. Myogenesis can be inhibited by serum components, purified mitogens, and transforming growth factors, but the intracellular signaling pathways utilized by these molecules are unknown.
M D, Schneider, E N, Olson
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Effects of growth factors on myogenic differentiation

American Journal of Physiology-Cell Physiology, 1989
It has now been well established that the terminal differentiation of muscle cells in culture is subject to control by hormones and growth factors in the incubation medium. Thus far the most potent and most extensively studied agents are fibroblast growth factor (FGF), the insulinlike growth factors (IGFs), and transforming growth factor-beta (TGF ...
J R, Florini, K A, Magri
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Myogenic Differentiation by Human Processed Lipoaspirate Cells

Plastic and Reconstructive Surgery, 2002
The use of undifferentiated cells for cell-based tissue engineering and regeneration strategies represents a promising approach for skeletal muscle repair. For such strategies to succeed, a readily available source of myogenic precursor cells must be identified. We have previously shown that cells isolated from raw human lipoaspirates, called processed
Hiroshi, Mizuno, Patricia A, Zuk, Min, Zhu, H Peter, Lorenz, Prosper, Benhaim, Marc H, Hedrick   +5 more
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Cutaneous mesenchymal hamartoma with mixed myogenous differentiation

Journal of Cutaneous Pathology, 2006
Abstract:A 3‐month‐old infant girl presented with a polypoid lesion in the perianal region. No changes in this lesion had been noted since birth. Microscopic examination of the excised specimen showed a mixture of mesenchymal elements, dominated by haphazard thin fascicles of skeletal muscle.
John Edwin, Schrecengost, Sana, Tabbara, James, Patterson, Mark R, Wick   +3 more
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Involvement of Hexose transport in myogenic differentiation

Journal of Cellular Physiology, 1990
AbstractA high (HAHT) and a low (LAHT) affinity hexose transport system are present in undifferentiated rat L6 myoblasts; however, only the latter can be detected in multinucleated myotubes. This suggests that HAHT is either down‐regulated or modified as a result of myogenesis.
P A, Kudo, T C, Lo
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Jun inhibits myogenic differentiation.

Oncogene, 1991
Myoblasts from skeletal muscle of chicken or Japanese quail embryos were infected with avian sarcoma virus 17 (ASV-17), a retrovirus carrying the jun oncogene. At high multiplicities of infection ASV-17-induced morphologic transformation inhibited fusion of myoblasts into myotubes and stimulated extended replication.
H Y, Su, T J, Bos, F S, Monteclaro, P K, Vogt   +3 more
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Myostatin is an inhibitor of myogenic differentiation

American Journal of Physiology-Cell Physiology, 2002
Myostatin (MSTN), a transforming growth factor (TGF)-β superfamily member, has been shown to negatively regulate muscle growth by inhibiting muscle precursor cell proliferation. Here, we stably transfected C2C12 cells with mouse MSTN cDNA to investigate its possible role in myoblast differentiation.
Ramón, Ríos, Isabel, Carneiro, Víctor M, Arce, Jesús, Devesa   +3 more
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Cutaneous extrarenal rhabdoid tumor with myogenic differentiation

Journal of Cutaneous Pathology, 2005
Background:  The rhabdoid phenotype is characterized by large epithelioid cells with abundant eosinophilic cytoplasm and paranuclear inclusions of intermediate filaments. Although originally described in tumors from pediatric kidneys, the rhabdoid phenotype has since been described in a variety of patient ages and extrarenal sites. Extraordinarily, the
Matthew, Petitt, Katherine, Doeden, Alexis, Harris, Thèrése, Bocklage   +3 more
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p130Cas-dependent actin remodelling regulates myogenic differentiation

Biochemical Journal, 2012
Actin dynamics are implicated in various cellular processes, not only through the regulation of cytoskeletal organization, but also via the control of gene expression. In the present study we show that the Src family kinase substrate p130Cas (Cas is Crk-associated substrate) influences actin remodelling and concomitant muscle-specific gene expression ...
Kawauchi, K., Tan, W.W., Araki, K., Abu Bakar, F.B., Kim, M., Fujita, H., Hirata, H., Sawada, Y.   +7 more
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A role for PKCε during C2C12 myogenic differentiation

Cellular Signalling, 2010
In a previous report we have demonstrated that PLCgamma1 is involved in the differentiation process of C2C12 myoblasts, induced by insulin administration. In order to identify the downstream targets of PLCgamma1-dependent signalling, we have analyzed the expression of DAG-dependent PKC isoforms during muscle differentiation. We show that during myotube
GABOARDI, GIAN CARLO, RAMAZZOTTI, GIULIA, Bavelloni A, PIAZZI, MANUELA, FIUME, ROBERTA, BILLI, ANNA MARIA, Matteucci A, FAENZA, IRENE, COCCO, LUCIO ILDEBRANDO   +8 more
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