Results 131 to 140 of about 4,549 (160)

Satellite cells and myonuclei in young and elderly women and men

Muscle & Nerve, 2003
AbstractThe overall aim of this study was to assess the effects of aging on the satellite cell population. Muscle biopsies were taken from the tibialis anterior muscle of healthy, moderately active young (age range, 20–32 years;n= 31) and elderly (age range, 70–83 years;n= 27) women and men with comparable physical activity pattern. Satellite cells and
Fawzi, Kadi, Nadia, Charifi, Christian, Denis, Jan, Lexell   +3 more
openaire   +2 more sources

Muscle Fiber Hypertrophy and Myonuclei Addition: A Systematic Review and Meta-analysis

Medicine and Science in Sports and Exercise, 2018
ABSTRACTIntroductionThe myonuclear domain theory postulates that myonuclei are added to muscle fibers when increases in fiber cross-sectional area (i.e., hypertrophy) are ≥26%. However, recent studies have reported increased myonuclear content with lower levels (e.g., 12%) of muscle fiber hypertrophy.PurposeThis study aimed to determine whether a ...
CARLOS Ugrinowitsch, Felipe Damas, Donny Camera   +2 more
exaly   +5 more sources

A distinctive type of infantile inflammatory myopathy with abnormal myonuclei

Journal of the Neurological Sciences, 1996
Four infants developed progressive muscle weakness after a normal initial postnatal development. All patients had a moderate elevation of serum creatine kinase (CK) activity. Muscle biopsies revealed, in addition to myopathic features, endomysial and perivascular inflammation.
N, Sripathi, G, Karpati, S, Carpenter
openaire   +2 more sources

Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging [PDF]

Aging Cell, 2017
SummarySkeletal muscle aging is accompanied by loss of muscle mass and strength. Examining changes in myonuclear proteins with age would provide insight into molecular processes which regulate these profound changes in muscle physiology. However, muscle tissue is highly adapted for contraction and thus comprised largely of contractile proteins making ...
Anita Corbett, Nicholas Seyfried, Grace Pavlath   +2 more
exaly   +3 more sources

MYONUCLEI ARE NOT LOST DURING MUSCLE ATROPHY

Journal of Experimental Biology, 2008
![Figure][1] We have all experienced the fact that skeletal muscles can change size. When we go to the gym and lift weights, our muscles get bigger. However, when we are lazy and stop working out, our muscles decrease in size.
openaire   +1 more source

Apoptotic myonuclei in human Duchenne muscular dystrophy.

Laboratory investigation; a journal of technical methods and pathology, 1998
The current view that apoptosis precedes necrosis in death of dystrophin-deficient muscle fibers of the mdx mouse has been well substantiated. Moreover, apoptotic myonuclei have been reported to increase in dystrophin-deficient mice 2 days after spontaneous exercise.
SANDRI M, MINETTI, CARLO, PEDEMONTE M, CARRARO U.   +3 more
openaire   +3 more sources

A myogenic regulatory gene, qmf1, is expressed by adult myonuclei after injury

American Journal of Physiology-Cell Physiology, 1993
Myogenic regulatory factors (MRFs) induce differentiation in developing muscle. We examined the role of MRFs in the repair of adult muscle using a model of stretch-induced injury in 5-wk-old chickens. The anterior latissimus dorsi muscle was stretched by loading the wing with 10% of body weight, while the contralateral muscle served as a control.
Z A, Eppley, J, Kim, B, Russell
openaire   +2 more sources

Numbers of myonuclei and satellite cell nuclei in latissimus dorsi muscles of the chicken

Cell and Tissue Research, 1987
In the 3-, 33- and 66-day-old chicken, two muscles, the oxidative slow tonic anterior latissimus dorsi and the glycolytic fast twitch posterior latissimus dorsi were compared by the measurement of muscle fibre diameter and the fraction of total muscle tissue nuclei which were either myonuclei or satellite cell nuclei.
C A, Matthew, M J, Moore
exaly   +3 more sources

The expanding roles of myonuclei in adult skeletal muscle health and function

Biochemical Society Transactions
Skeletal muscle cells (myofibers) require multiple nuclei to support a cytoplasmic volume that is larger than other mononuclear cell types. It is dogmatic that mammalian resident myonuclei rely on stem cells (specifically satellite cells) for adding new DNA to muscle fibers to facilitate cytoplasmic expansion that occurs during muscle growth.
Agnieszka K. Borowik, Kevin A. Murach, Benjamin F. Miller   +2 more
openaire   +2 more sources

Adaptations of myonuclei to hypertrophy in patagialis muscle fibers from aged quail

Mechanisms of Ageing and Development, 1996
Hypertrophic responses to stretch are attenuated in slow-tonic muscles from old quail, relative to young birds. It is not known if the age-associated differences would be similar in fast-twitch muscles after stretch. This study compared the effect of 30 days of stretch overload on slow beta fibers and fast-alpha fibers in patagialis (PAT) muscles from ...
J, Lee, S E, Alway
openaire   +2 more sources