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Displaced myonuclei in cancer cachexia suggest altered innervation
Introduction. Central nuclei are considered a hallmark of skeletal muscle fiber regeneration and a sign of myopathy. We and others have previously observed central myonuclei in both pre-cachectic patients and animal models of cancer cachexia, in striking contrast with the reduced regenerative potential characterizing cachectic muscles. Methods.Coletti Dario +9 more
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Muscle déjà vu: are myonuclei the blueprint for muscle regrowth?
The Journal of PhysiologyClaire Traversa +3 more
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