Results 141 to 150 of about 380,707 (403)

Stochastic Ratcheting on a Funneled Energy Landscape is Necessary for Highly Efficient Contractility of Actomyosin Force Dipoles

, 2017
Current understanding of how contractility emerges in disordered actomyosin networks of non-muscle cells is still largely based on the intuition derived from earlier works on muscle contractility.
Komianos, James E., Papoian, Garegin A.
core   +2 more sources

Muscle Organoids Reveal Exercise‐Like Contractions Rapidly Promote Muscle Health Via Lamtor1's Signaling to Both AMPK and mTOR

Advanced Science, EarlyView.
This study develops a novel 3D human skeletal muscle organoid platform to study the immediate molecular effects of exercise‐like contractions. The model uncovers rapid proteomic and transcriptomic responses, resolving a fundamental paradox by demonstrating how exercise‐induced Lamtor1 coordinately activates both AMPK and mTORC1. Lamtor1 is a compelling
Ziyue Yao, Zongmin Jiang, Xupeng Liu, Liping Zhang, Siyu Guo, Yu Chen, Lanfang Luo, Shilin Ma, Peng Wang, Ng Shyh‐Chang   +9 more
wiley   +1 more source

Polarity sorting drives remodeling of actin-myosin networks [PDF]

, 2018
Viktoria Wollrab, Julio M. Belmonte, Lucia Baldauf, Maria Leptin, François Nédélec, Gijsje H. Koenderink   +5 more
openalex   +1 more source

Chromosome movement in lysed mitotic cells is inhibited by vanadate. [PDF]

, 1978
Mitotic PtK1 cells, lysed at anaphase into a carbowax 20 M Brij 58 solution, continue to move chromosomes toward the spindle poles and to move the spindle poles apart at 50% in vivo rates for 10 min.
CANDE, W. Zacheus, Wolniak, S
core   +1 more source

Molecular Model of the Contractile Ring

, 2005
We present a model for the actin contractile ring of adherent animal cells. The model suggests that the actin concentration within the ring and consequently the power that the ring exerts both increase during contraction.
D. Biron, D. Biron, D. Humphrey, D. H. Boal, E. Alvarez-Lacalle, E. Moses, I. Mabuchi, I. Mabuchi, J. Howard, O. Thoumine, R. Rappaport, R. L. Debiasio, T. Tlusty, T. D. Pollard, T. E. Schroeder, T. E. Schroeder   +15 more
core   +1 more source

Cell Contractile Force‐Mediated Morphogenetic Tissue Engineering via 4D Printed Degradable Hydrogel Scaffolds

Advanced Science, EarlyView.
Through the actuation of cell contractile forces, geometrically complex structures are formed via a bioprinted, rapidly degrading cell‐laden hydrogel system, resulting in cell‐only condensation within a few days of culture. This system supports stem cell differentiation down different lineages and new tissue formation, such as chondrogenesis and ...
Aixiang Ding, Kaelyn L. Gasvoda, David S. Cleveland, Sriramya Ayyagari, Eben Alsberg   +4 more
wiley   +1 more source

Identification and characterization of the Bombyx mori myosin II essential light chain and its effect in BmNPV infection

Invertebrate Survival Journal, 2015
Myosin, as a type of molecular motor, is mainly involved in muscle contraction. Recently, myosin research has made considerable progress. However, the function of Bombyx mori myosin remains unclear.
L J Hao, P Lü, L Gao, Y Zhou, Q Yao, Y H Yang, K P Chen   +6 more
doaj  

In vivo interactions between myosin XI, vesicles and filamentous actin are fast and transient in Physcomitrella patens [PDF]

, 2020
Jeffrey P. Bibeau, Fabienne Furt, Sayed Iman Mousavi, James L. Kingsley, Max F. Levine, Erkan Tüzel, Luis Vidali   +6 more
openalex   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

Advanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Mechanism of Blebbistatin Inhibition of Myosin II*

Journal of Biological Chemistry, 2004
Blebbistatin is a recently discovered small molecule inhibitor showing high affinity and selectivity toward myosin II. Here we report a detailed investigation of its mechanism of inhibition.
M. Kovács, J. Tóth, C. Hetényi, A. Málnási-Csizmadia, J. Sellers   +4 more
semanticscholar   +1 more source