Results 201 to 210 of about 287,774 (303)

Editorial: Hypertrophic Cardiomyopathy and Precision Medicine in Cardiovascular Disease. [PDF]

Med Sci Monit
Parums DV.
europepmc   +1 more source

Mechanosensing in Dendritic Cells. [PDF]

Immunol Rev
Calmettes V, Quintanilla MA, Lacerda Mariano L, Piel M, Moreau HD, Lennon-Duménil AM.   +5 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Dual modes of contractility tailor cytokinesis to the requirements of diverse tissues. [PDF]

iScience
Deduyer I, Montembault E, Claverie MC, Touly N, McCusker D, Royou A.   +5 more
europepmc   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

Dynamics of full-length Arabidopsis myosin XI and its involvement in actin remodeling. [PDF]

Plant Cell Physiol
Obara J, Tominaga M.
europepmc   +1 more source

Prevalence and Mechanisms of Sustained Force Production in the Musculature of the Southern Alligator Lizard (Elgaria multicarinata)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The southern alligator lizard (Elgaria multicarinata) exhibits prolonged mate‐holding behavior. This behavior maybe be underpinned by a phenomenon known as sustained force, observed in the jaw muscles of this species, in which the muscle fails to relax between subsequent contractions.
Allyn Nguyen, Kyle Leong, Jessica Phan, Natalie Holt   +3 more
wiley   +1 more source

Comparing the Efficacy of Myosin Inhibition Versus Thin Filament Calcium Desensitization for Treatment of Pediatric Restrictive Cardiomyopathy Using a Patient-Derived hiPSC Model. [PDF]

Circ Genom Precis Med
Staudt DW, Serrano R, Hnatiuk AP, Sanchez I, Carhuamaca X, Feyen DAM, Mercola M.   +6 more
europepmc   +1 more source