Results 21 to 30 of about 40,761 (237)
Myosins VIII and XI play distinct roles in reproduction and transport of tobacco mosaic virus.
PLoS Pathogens, 2014 Viruses are obligatory parasites that depend on host cellular factors for their replication as well as for their local and systemic movement to establish infection.
Khalid Amari +3 more
doaj +1 more source
Frontiers in Physiology, 2018 Elevated levels of the metabolic by-products, including acidosis (i.e., high [H+]) and phosphate (Pi) are putative agents of muscle fatigue; however, the mechanism through which they affect myosin’s function remain unclear. To elucidate these mechanisms,
Mike Woodward, Edward P. Debold
doaj +1 more source
Thick filament‐associated myosin undergoes frequent replacement at the tip of the thick filament
FEBS Open Bio, 2022 Myosin plays a fundamental role in muscle contraction. Approximately 300 myosins form a bipolar thick filament, in which myosin is continuously replaced by protein turnover.
Emi Ichimura +4 more
doaj +1 more source
Distribution and evolution of stable single α-helices (SAH domains) in myosin motor proteins. [PDF]
PLoS ONE, 2017 Stable single-alpha helices (SAHs) are versatile structural elements in many prokaryotic and eukaryotic proteins acting as semi-flexible linkers and constant force springs.
Dominic Simm, Klas Hatje, Martin Kollmar
doaj +1 more source
Myosin V-mediated transport of Snc1 and Vps10 toward the trans-Golgi network
European Journal of Cell Biology, 2021 Retrieval of cargo proteins from the endosome towards the trans-Golgi network (TGN) is a crucial intracellular process for cellular homeostasis. Its dysfunction is associated with pathogenesis of Alzheimer and Parkinson's diseases. Myosin family proteins
Vy Nguyen +6 more
doaj +1 more source
Evolutionary Bioinformatics, 2016 Myosins are actin-based motor proteins involved in many cellular movements. It is interesting to study the evolutionary patterns and the functional attributes of various types of myosins.
Shaik Naseer Pasha +2 more
doaj +1 more source
Type-I myosins promote actin polymerization to drive membrane bending in endocytosis
eLife, 2019 Clathrin-mediated endocytosis in budding yeast requires the formation of a dynamic actin network that produces the force to invaginate the plasma membrane against the intracellular turgor pressure.
Hetty E Manenschijn +5 more
doaj +1 more source
Unravelling the molecular basis of the dominant negative effect of myosin XI tails on P-bodies.
PLoS ONE, 2021 The directional movement and positioning of organelles and macromolecules is essential for regulating and maintaining cellular functions in eukaryotic cells.
Lisa Stephan +4 more
doaj +1 more source
The ancient sarcomeric myosins found in specialized muscles
Skeletal Muscle, 2019 Striated muscles express an array of sarcomeric myosin motors that are tuned to accomplish specific tasks. Each myosin isoform found in muscle fibers confers unique contractile properties to the fiber in order to meet the demands of the muscle.
Lindsey A. Lee +3 more
doaj +1 more source
Myosin-Powered Membrane Compartment Drives Cytoplasmic Streaming, Cell Expansion and Plant Development. [PDF]
PLoS ONE, 2015 Using genetic approaches, particle image velocimetry and an inert tracer of cytoplasmic streaming, we have made a mechanistic connection between the motor proteins (myosins XI), cargo transported by these motors (distinct endomembrane compartment defined
Valera V Peremyslov +3 more
doaj +1 more source