Distribution and evolution of stable single α-helices (SAH domains) in myosin motor proteins. [PDF]
PLoS ONE, 2017 Stable single-alpha helices (SAHs) are versatile structural elements in many prokaryotic and eukaryotic proteins acting as semi-flexible linkers and constant force springs.
Dominic Simm, Klas Hatje, Martin Kollmar
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Nuclear actin and myosins in adenovirus infection [PDF]
, 2015 Adenovirus serotypes have been shown to cause drastic changes in nuclear organization, including the transcription machinery, during infection. This ability of adenovirus to subvert transcription in the host cell facilitates viral replication.
De Lanerolle, Primal +2 more
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Thick filament‐associated myosin undergoes frequent replacement at the tip of the thick filament
FEBS Open Bio, 2022 Myosin plays a fundamental role in muscle contraction. Approximately 300 myosins form a bipolar thick filament, in which myosin is continuously replaced by protein turnover.
Emi Ichimura +4 more
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Myosin V-mediated transport of Snc1 and Vps10 toward the trans-Golgi network
European Journal of Cell Biology, 2021 Retrieval of cargo proteins from the endosome towards the trans-Golgi network (TGN) is a crucial intracellular process for cellular homeostasis. Its dysfunction is associated with pathogenesis of Alzheimer and Parkinson's diseases. Myosin family proteins
Vy Nguyen +6 more
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Insights into the origin of metazoan filopodia and microvilli. [PDF]
, 2013 Filopodia are fine actin-based cellular projections used for both environmental sensing and cell motility, and they are essential organelles for metazoan cells. In this study, we reconstruct the origin of metazoan filopodia and microvilli.
Burkhardt, Pawel +6 more
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BMC Plant Biology, 2012 Background The positioning and dynamics of vesicles and organelles, and thus the growth of plant cells, is mediated by the acto-myosin system. In Arabidopsis there are 13 class XI myosins which mediate vesicle and organelle transport in different cell ...
Ojangu Eve-Ly +6 more
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Type-I myosins promote actin polymerization to drive membrane bending in endocytosis
eLife, 2019 Clathrin-mediated endocytosis in budding yeast requires the formation of a dynamic actin network that produces the force to invaginate the plasma membrane against the intracellular turgor pressure.
Hetty E Manenschijn +5 more
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Unravelling the molecular basis of the dominant negative effect of myosin XI tails on P-bodies.
PLoS ONE, 2021 The directional movement and positioning of organelles and macromolecules is essential for regulating and maintaining cellular functions in eukaryotic cells.
Lisa Stephan +4 more
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Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells [PDF]
, 2016 Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal ...
Hafner, Anne E., Rieger, Heiko
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Teaming up: from motors to people. [PDF]
, 2013 When I reflect on how I became a cell biologist and why I love being one today, one thing that comes to mind is the many terrific collaborations I have had.
Reck-Peterson, Samara L
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