Results 31 to 40 of about 18,015 (263)
Involvement of DPY19L3 in Myogenic Differentiation of C2C12 Myoblasts
Molecules, 2021 DPY19L3 has been identified as a C-mannosyltransferase for thrombospondin type-1 repeat domain-containing proteins. In this study, we focused on the role of DPY19L3 in the myogenic differentiation of C2C12 mouse myoblast cells.
Kento Mori +3 more
doaj +1 more source
The Role of Embryonic Chick Muscle Cell Culture in the Study of Skeletal Myogenesis
Frontiers in Physiology, 2021 The mechanisms involved in the development of skeletal muscle fibers have been studied in the last 70 years and yet many aspects of this process are still not completely understood.
Manoel L. Costa +3 more
doaj +1 more source
Frontiers in Physiology, 2020 Mouse olfactory receptor 544 (Olfr544) is ectopically expressed in varied extra-nasal organs with tissue specific functions. Here, we investigated the functionality of Olfr544 in skeletal muscle cells and tissue. The expression of Olfr544 is confirmed by
Trung Thanh Thach +6 more
doaj +1 more source
Cellular and Genomic Features of Muscle Differentiation from Isogenic Fibroblasts and Myoblasts
Cells, 2023 The ability to recapitulate muscle differentiation in vitro enables the exploration of mechanisms underlying myogenesis and muscle diseases. However, obtaining myoblasts from patients with neuromuscular diseases or from healthy subjects poses ethical and
Louise Benarroch +9 more
doaj +1 more source
The nucleotide receptors on mouse C2C12 myotubes [PDF]
British Journal of Pharmacology, 1992 1. The response of C2C12 mouse myotubes to stimulation with adenosine triphosphate (ATP) and other nucleotides was studied by measuring changes in membrane potential. 2. A transient hyperpolarization followed by a slowly declining depolarization of the cells was observed in the presence of ATP (10 microM-1 mM). 3. The hyperpolarization was not observed
Henning, R.H. +3 more
openaire +2 more sources
Development of an in vitro model of myotube ischemia [PDF]
Laboratory Investigation, 2011 Critical limb ischemia causes severe damage to the skeletal muscle. This study develops a reproducible model of myotube ischemia by simulating, in vitro, the critical parameters that occur in skeletal muscle ischemia. Monolayers of C2C12 myoblasts were differentiated into mature myotubes and exposed to nutrition depletion, hypoxia and hypercapnia for ...
Dhiraj, Joshi +5 more
openaire +2 more sources
Frontiers in Cell and Developmental Biology, 2023 To produce muscle fibers for cultured meat on a large scale, it is important to expand myoblasts in a serum-reduced or serum-free medium to avoid cost, ethical, and environmental issues.
Tomoka Katayama +2 more
doaj +1 more source
Netrins and neogenin promote myotube formation [PDF]
The Journal of Cell Biology, 2004 Differentiation of skeletal myoblasts into multinucleated myotubes is a multistep process orchestrated by several families of transcription factors, including myogenic bHLH and NFAT proteins. The activities of these factors and formation of myotubes are regulated by signal transduction pathways, but few extracellular factors that might initiate such ...
Kang, Jong-Sun +5 more
openaire +2 more sources
Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase [PDF]
, 2023 The Warburg effect links growth and glycolysis in cancer. A key purpose of the Warburg effect is to generate glycolytic intermediates for anabolic reactions, such as nucleotides → RNA/DNA and amino acids → protein synthesis.
Gabriel, Brendan M. +27 more
core +1 more source
Physiological Reports, 2019 Much is known about the positive effects of branched‐chain amino acids (BCAA) in regulating muscle protein metabolism. Comparatively much less is known about the effects of these amino acids and their metabolites in regulating myotube formation.
Zameer N. Dhanani +2 more
doaj +1 more source