Results 71 to 80 of about 18,015 (263)

Transwell membrane material affects myogenic differentiation in human primary myoblast-adipocyte co-culture. [PDF]

Physiol Rep
Abstract Transwell co‐culture systems are models for examining cellular crosstalk, but the impact of porous membrane material on myogenic outcomes remains uncharacterized. We investigated the influence of transwell membrane material on myoblast differentiation in co‐culture with human primary adipocytes and in varying concentrations of insulin ...
Plissonneau C, Tam BT, Garneau PY, Morais JA, Piekny A, Santosa S.   +5 more
europepmc   +2 more sources

Schematic representation of cantilever deflection system for recording myotube contractions.

, 2013
Schematic representation of cantilever deflection system for recording myotube contractions.
James Hickman (364199), Kerry Wilson (364195), Mainak Das (364196), Kathryn J. Wahl (364197), Richard J. Colton (364198)   +4 more
core   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Effects of Maillard Reaction Products on Skeletal Muscle Cells: An In Vitro Study Using C2C12 Myotubes

Metabolites
Background: Maillard reaction products (MRPs) are known for their antioxidant properties; however, their effects on muscle cells remain unclear. This study aims to elucidate the effects of MRPs on muscle hypertrophy and atrophy in C2C12 myotubes. Methods:
Marina Miyaki, Yusuke Komiya, Itsuki Sumiya, Rina Yamaguchi, Moeka Kuno, Chika Kojima, Ryosuke Makino, Takahiro Suzuki, Yoshihiro Suzuki, Issei Yokoyama, Keizo Arihara   +10 more
doaj   +1 more source

Notch Inhibition via GSI Treatment Elevates Protein Synthesis in C2C12 Myotubes

Biology, 2020
The role of Notch signaling is widely studied in skeletal muscle regeneration but little is known about its influences on muscle protein synthesis (MPS).
Joshua R. Huot, Joseph S. Marino, Michael J. Turner, Susan T. Arthur   +3 more
doaj   +1 more source

Activation of IGF-1 pathway and suppression of atrophy related genes are involved in Epimedium extract (icariin) promoted C2C12 myotube hypertrophy

Scientific Reports, 2021
The regenerative effect of Epimedium and its major bioactive flavonoid icariin (ICA) have been documented in traditional medicine, but their effect on sarcopenia has not been evaluated.
Yi-An Lin, Yan-Rong Li, Yi-Ching Chang, Mei-Chich Hsu, Szu-Tah Chen   +4 more
doaj   +1 more source

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

Advanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong, Tuba Marjan, Ngoc Ha Luong, Taimoor H. Qazi, Chien‐Chi Lin   +4 more
wiley   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

Advanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang, Xiuying Jiang, Xi Sun, Hao Chen, Jianjun Jin, Xin'e Shi   +5 more
wiley   +1 more source

The dose–response effects of arachidonic acid on primary human skeletal myoblasts and myotubes

Journal of the International Society of Sports Nutrition, 2023
Background Cellular inflammatory response, mediated by arachidonic acid (AA) and cyclooxygenase, is a highly regulated process that leads to the repair of damaged tissue.
Brandon M. Roberts, Alexander L. Kolb, Alyssa V. Geddis, Marshall A. Naimo, Ronald W. Matheny   +4 more
doaj   +1 more source