Results 81 to 90 of about 18,015 (263)

Human derived tendon cells contribute to myotube formation in vitro

, 2022
Skeletal muscle possesses remarkable adaptability to mechanical loading and regenerative potential following muscle injury primarily due to satellite cell activity.
Bayer, Monika Lucia, Schjerling, Peter, Tsuchiya, Yoshifumi, Kjaer, Michael, Soendenbroe, Casper   +4 more
core   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Continuous exposure to isoprenaline reduced myotube size by delaying myoblast differentiation and fusion through the NFAT-MEF2C signaling pathway

Scientific Reports, 2023
We aimed to explore whether superfluous sympathetic activity affects myoblast differentiation, fusion, and myofiber types using a continuous single-dose isoprenaline exposure model in vitro and to further confirm the role of distinct NFATs in ISO ...
Jing Yue, Wei Xu, Li Xiang, Shao-juan Chen, Xin-yuan Li, Qian Yang, Ruo-nan Zhang, Xin Bao, Yan Wang, MagdaleenaNaemi Mbadhi, Yun Liu, Lu-yuan Yao, Long Chen, Xiao-ying Zhao, Chang-qing Hu, Jing-xuan Zhang, Hong-tao Zheng, Yan Wu, Shi-You Chen, Shan Li, Jing Lv, Liu-liu Shi, Jun-ming Tang   +22 more
doaj   +1 more source

Morphological comparison of myoblast and myotube nuclei.

, 2013
Nuclei of differentiated myotubes have been characterised by a smaller volume (A) and increased flattening (B) compared to proliferating myoblasts.
Maciej Kurpisz (362146), Piotr Pawlak (140082), Tomasz Mietkiewski (453371), Marcin Siatkowski (171726), Tomasz Kolanowski (453368), Agnieszka Malcher (453370), Marta Olszewska (453372), Natalia Rozwadowska (453367), Ewa Wiland (453369)   +8 more
core   +1 more source

ZBED6 Knockout Promotes Skeletal Muscle Development in Bama Pigs by Relieving Transcriptional Repression of CDKN1A

Animal Research and One Health, EarlyView.
Integrated transcriptomic and functional analyses identify CDKN1A as a direct target of ZBED6 in Bama pigs. ZBED6 knockout relieves transcriptional repression of CDKN1A, thereby promoting myogenic differentiation and skeletal muscle development.
Yitian Ma, Xiu Lin, Pengtao Yuan, Yabin Pu, Yuehui Ma, Zixiao Jiang, Lin Jiang, Chongyang Li, Dandan Wang   +8 more
wiley   +1 more source

Orai1 channels in skeletal myotubes [PDF]

Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology, 2009
ISSN 1990-7478, Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology, 2009, Vol. 3, No. 3, p. 299. © Pleiades Publishing, Ltd., 2009.Original Russian Text © P.V. Avdonin, I.B. Sukhanova, K.V. Surkov, O. Petermann, U.T. Rueggc, 2009, published in Biologicheskie Membrany, 2009, Vol. 26, No. 4, p. 305.
P. V. Avdonin, I. B. Sukhanova, K. V. Surkov, O. Petermann, U. T. Ruegg   +4 more
openaire   +1 more source

Graphene Foam as a Three-Dimensional Platform for Myotube Growth

, 2016
This study demonstrates the growth and differentiation of C2C12 myoblasts into functional myotubes on three-dimensional graphene foam bioscaffolds. Specifically, we establish both bare and laminin-coated graphene foam as a biocompatible platform for ...
Chang, A. Nicole, Cantley, Kurtis D., David Estrada (486190), Krueger, Eric, Eixenberger, Josh, Sepideh Rastegar (2870036), Raquel Brown (2870033), Dale Brown (2870024), Brown, Dale, Brown, Raquel, Josh Eixenberger (2870030), Katie M. Yocham (2870018), Rastegar, Sepideh, A. Nicole Chang (2870027), Yocham, Katie M., Estrada, David, Eric Krueger (2870015), Kurtis D. Cantley (2870021)   +17 more
core   +1 more source

Morphology-Based Analysis of Myoblasts for Prediction of Myotube Formation [PDF]

, 2019
The development of new drugs depends on the efficiency of drug screening. Phenotype-based screening has attracted interest due to its considerable potency for the discovery of first-in-class drugs. In general, fluorescently labeled imagery is the leading
Kanie, Kei, Yoshida, Kei, Kato, Ryuji, Omori, Kenji, Ishikawa, Kiyoshi   +4 more
core   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source