Results 21 to 30 of about 47,831 (279)

N-acetylcysteine as an adjunct treatment of schizophrenia

open access: yesEuropean Psychiatry, 2021
Introduction An increasing body of literature supports the hypothesis that immune imbalance towards a pro-inflammatory status in the brain plays an important role in schizophrenia.
R. Mota Freitas, M.T. Valadas
doaj   +1 more source

The effect of N-acetylcysteine on mechanical fatigue resistance of antibiotic-loaded bone cement

open access: yesJournal of Orthopaedic Surgery and Research, 2018
Background This biomechanical study evaluates the effect of N-acetylcysteine alone and in combination with the most commonly used antibiotic-loaded bone cement mixtures.
Erhan Sukur   +5 more
doaj   +1 more source

Both PKA and Epac pathways mediate N-acetylcysteine-induced Connexin43 preservation in rats with myocardial infarction. [PDF]

open access: yesPLoS ONE, 2013
Cardiac remodeling was shown to be associated with reduced gap junction expression after myocardial infarction. A reduction in gap junctional proteins between myocytes may trigger ventricular arrhythmia.
Tsung-Ming Lee   +2 more
doaj   +1 more source

Effects of melatonin and N-acetylcysteine on aluminum phosphide poisoning in rats

open access: yesJournal of Family Medicine and Primary Care, 2022
Introduction: Aluminum phosphide (ALP) poisoning is one of the deadliest types of poisoning in the world. The antioxidant properties of melatonin and N-acetylcysteine and their effects on reducing cell death have been identified.
Ramin Parvizrad   +3 more
doaj   +1 more source

N-Acetylcysteine Restores Sevoflurane Postconditioning Cardioprotection against Myocardial Ischemia-Reperfusion Injury in Diabetic Rats

open access: yesJournal of Diabetes Research, 2016
The effect of sevoflurane postconditioning (sevo-postC) cardioprotection is compromised in diabetes which is associated with increased oxidative stress. We hypothesized that antioxidant N-Acetylcysteine may enhance or restore sevo-postC cardioprotection ...
Jiefu Lin   +6 more
doaj   +1 more source

N-acetylcysteine in dermatology

open access: yesIndian Journal of Dermatology, Venereology and Leprology, 2018
N-acetylcysteine is a mucolytic drug which is commonly used as an antidote for acetaminophen toxicity. It is a thiol compound, which acts as a donor of cysteine, leading to replenishment of glutathione and thus acts as an antioxidant. It also has anti-inflammatory effects, alters the levels of neurotransmitters, inhibits proliferation of fibroblasts ...
Mohammad, Adil   +2 more
openaire   +2 more sources

GSH rescue by N-acetylcysteine [PDF]

open access: yesKlinische Wochenschrift, 1991
Reduced glutathione (GSH) is the main intracellular low molecular weight thiol. GSH acts as a nucleophilic scavenger and as an enzyme-catalyzed antioxidant in the event of electrophilic/oxidative tissue injury. Therefore, GSH has a major role as a protector of biological structures and functions.
Ruffmann, R., Wendel, A.
openaire   +2 more sources

A simple, sensitive and cost-effective electrochemical sensor for the determination of N-acetylcysteine

open access: yesJournal of Electrochemical Science and Engineering, 2023
In the present work, we prepared a simple and novel electrochemical sensor based on zeolitic imidazolate framework-67 (ZIF-67) and ionic liquid 1-Butyl-3-methylimidazolium hexa­fluorophosphate (BMIM.PF6) modified carbon paste electrode (CPE), which was ...
Somayeh Tajik   +2 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Betamethasone was more Effective than N-acetylcysteine for Lung Maturation

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2013
Objective: To compare the effectivity of N-acetylcysteine with Betamethasone in fetal lung maturation. Methods: This research was a double blind randomized clinical trials in women threatened by preterm delivery (28 to 34 weeks of gestation).
Fatmah Oktaviani
doaj   +1 more source

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