Results 51 to 60 of about 4,942 (222)

Characterization and Engineering Studies of a New Endolysin from the Propionibacterium acnes Bacteriophage PAC1 for the Development of a Broad-Spectrum Artilysin with Altered Specificity

International Journal of Molecular Sciences, 2023
The emergence of multidrug-resistant (MDR) bacteria has risen rapidly, leading to a great threat to global public health. A promising solution to this problem is the exploitation of phage endolysins.
Christina Varotsou, Georgios E Premetis, N. Labrou   +2 more
semanticscholar   +1 more source

Peptide Occurring in Enterobacteriaceae Triggers Streptococcus pneumoniae Cell Death

Frontiers in Cellular and Infection Microbiology, 2019
Non-encapsulated Streptococcus pneumoniae often possess two genes, aliB-like ORF 1 and aliB-like ORF 2, in place of capsule genes. AliB-like ORF 1 is thought to encode a substrate binding protein of an ABC transporter which binds peptide SETTFGRDFN ...
Fauzy Nasher, Fauzy Nasher, Min Jung Kwun, Nicholas J. Croucher, Manfred Heller, Lucy J. Hathaway   +5 more
doaj   +1 more source

Proinflammatory bacterial peptidoglycan as a cofactor for the development of central nervous system autoimmune disease [PDF]

, 2005
Upon stimulation by microbial products through TLR, dendritic cells (DC) acquire the capacity to prime naive T cells and to initiate a proinflammatory immune response.
Boven, L.A. (Leonie), Heer, H.J. de, Laman, J.D. (Jon), Lambrecht, B.N.M. (Bart), Melief, M.J. (Marie-José), Meurs, M. (Marjan) van, Nieuwenhuis, E.E.S. (Edward), Riel, D.A.J. (Debby) van, Strijp, J. van, Visser, L. (Lizette), Zahringer, U.   +10 more
core   +2 more sources

The First Paenibacillus larvae Bacteriophage Endolysin (PlyPl23) with High Potential to Control American Foulbrood. [PDF]

PLoS ONE, 2015
Endolysins, which are peptidoglycan-degrading enzymes expressed during the terminal stage of the reproduction cycle of bacteriophages, have great potential to control Gram-positive pathogens. This work describes the characterization of a novel endolysin (
Ana Oliveira, Marta Leite, Leon D Kluskens, Sílvio B Santos, Luís D R Melo, Joana Azeredo   +5 more
doaj   +1 more source

Complete Genome Sequences of Paenibacillus Larvae Phages BN12, Dragolir, Kiel007, Leyra, Likha, Pagassa, PBL1c, and Tadhana [PDF]

, 2018
We present here the complete genomes of eight phages that infect Paenibacillus larvae, the causative agent of American foulbrood in honeybees. Phage PBL1c was originally isolated in 1984 from a P.
Berg, Jordan A., Breakwell, Donald P., Dhalai, Aziza, Dingman, Douglas W., Fajardo, Chris P., Graves, Kiel, Grose, Julianne H., Hill, Hunter L., Hilton, Jared A., Hope, Sandra, Imahara, Cameron, Knabe, Bradley K., Mangohig, James, Merrill, Bryan D., Monk, Josh, Mun, Heejin, Payne, Ashley M., Salisbury, Alicia, Stamereilers, Casey, Tsourkas, Philippos K., Velez, Kathie, Walker, Jamison K., Ward, Andy T.   +22 more
core   +2 more sources

Single-peptide DNA-dependent RNA polymerase homologous to multi-subunit RNA polymerase [PDF]

, 2017
Transcription in all living organisms is accomplished by multi-subunit RNA polymerases (msRNAPs). msRNAPs are highly conserved in evolution and invariably share a B400 kDa five-subunit catalytic core.
Forrest, David, James, Katherine, Yuzenkova, Yulia, Zenkin, Nikolay   +3 more
core   +2 more sources

A Thermophilic Phage Endolysin Fusion to a Clostridium perfringens-Specific Cell Wall Binding Domain Creates an Anti-Clostridium Antimicrobial with Improved Thermostability

Viruses, 2015
Clostridium perfringens is the third leading cause of human foodborne bacterial disease and is the presumptive etiologic agent of necrotic enteritis among chickens. Treatment of poultry with antibiotics is becoming less acceptable.
Steven M. Swift, Bruce S. Seal, Johnna K. Garrish, Brian B. Oakley, Kelli Hiett, Hung-Yueh Yeh, Rebekah Woolsey, Kathleen M. Schegg, John Eric Line, David M. Donovan   +9 more
doaj   +1 more source

Expression and delivery of an endolysin to combat Clostridium perfringens [PDF]

, 2013
Clostridium perfringens is a cause for increasing concern due to its responsibility for severe infections both in humans and animals, especially poultry. To find new control strategies to treat C.
Arjan Narbad, Giacomo Dugo, Melinda J. Mayer, Nikki Horn, Teresa Gervasi, Udo Wegmann   +5 more
core   +1 more source

Pan-Genome-Wide Analysis of Pantoea ananatis Identified Genes Linked to Pathogenicity in Onion

Frontiers in Microbiology, 2021
Pantoea ananatis, a gram negative and facultative anaerobic bacterium is a member of a Pantoea spp. complex that causes center rot of onion, which significantly affects onion yield and quality.
Gaurav Agarwal, Divya Choudhary, Shaun P. Stice, Brendon K. Myers, Ronald D. Gitaitis, Stephanus N. Venter, Brian H. Kvitko, Bhabesh Dutta   +7 more
doaj   +1 more source

Exploring Codon Adjustment Strategies towards Escherichia coli-Based Production of Viral Proteins Encoded by HTH1, a Novel Prophage of the Marine Bacterium Hypnocyclicus thermotrophus

Viruses, 2021
Marine viral sequence space is immense and presents a promising resource for the discovery of new enzymes interesting for research and biotechnology. However, bottlenecks in the functional annotation of viral genes and soluble heterologous production of ...
Hasan Arsın, Andrius Jasilionis, Håkon Dahle, Ruth-Anne Sandaa, Runar Stokke, Eva Nordberg Karlsson, Ida Helene Steen   +6 more
doaj   +1 more source