N-acetylmuramoyl-L-alanine amidase : A competent vaccine candidate against IPSID
, 2022 Immunoproliferative small intestine disease (IPSID) is a collective name for a range of diseases caused by various microorganisms but the major and persistent organism is Campylobacter Jejuni. IPSID can lead to minor symptoms like diarrhea, nausea, imbalance of electrolytes in the body etc.
yukti sabikhi +9 more
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The N-acetylmuramoyl-L-alanine amidase encoded by the Bacillus subtilis 168 prophage SPβ [PDF]
Microbiology, 1998 Heat shock ofBacillus subtilisCU1147, a strain lysogenic for SPβc2, a prophage with a thermosensitive repressor, results in phage induction and subsequent cell lysis. Cloning inEscherichia coliand sequencing of a DNA fragment of prophage SPβ led to the identification ofblyA, the gene encoding a 367 amino acid polypetide with a molecular mass of 39.6 ...
Alexandre, Regamey, Dimitri, Karamata
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Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis. [PDF]
PLoS ONE, 2013 Pathogenic bacteria interacting with eukaryotic host express adhesins on their surface. These adhesins aid in bacterial attachment to the host cell receptors during colonization.
Sanjiv Kumar +4 more
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Antibiotics, 2021 The main objective of this study was to characterize using whole-genome sequencing analysis, a new variant of the qnrB gene (qnrB89) carried by a fluoroquinolone-susceptible bacterium isolated from mucus of farmed Salmo salar fingerling in Chile ...
Christopher Concha +4 more
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CodY, a pleiotropic regulator, influences multicellular behaviour and efficient production of virulence factors in Bacillus cereus [PDF]
, 2012 In response to nutrient limitation in the environment, the global transcriptional regulator CodY modulates various pathways in low G+C Gram-positive bacteria.
Basset, Coraline +6 more
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Characteristics of a broad lytic spectrum endolysin from phage BtCS33 of
BMC Microbiology, 2012 Background Endolysins produced by bacteriophages lyse bacteria, and are thus considered a novel type of antimicrobial agent. Several endolysins from Bacillus phages or prophages have previously been characterized and used to target Bacillus strains that ...
Yuan Yihui, Peng Qin, Gao Meiying
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Comparative Genomics of 9 Novel Paenibacillus Larvae Bacteriophages [PDF]
, 2016 American Foulbrood Disease, caused by the bacterium Paenibacillus larvae, is one of the most destructive diseases of the honeybee, Apis mellifera. Our group recently published the sequences of 9 new phages with the ability to infect and lyse P.
Amy, Penny S. +4 more
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Functional characterization of a short peptidoglycan recognition protein from Chinese giant salamander (Andrias davidianus) [PDF]
, 2017 This work was supported by the National Natural Science Foundation of China (Grant no. 31302221, 31172408 and 31272666) and Jiangsu Province (Grant no.
Chang, Mingxian +8 more
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How innate immunity proteins kill bacteria and why they are not prone to resistance [PDF]
, 2017 Recent advances on antibacterial activity of peptidoglycan recognition proteins (PGRPs) offer some insight into how innate immunity has retained its antimicrobial effectiveness for millions of years with no frequent emergence of resistant strains. First,
Dziarski, Roman, Gupta, Dipika
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Mutational Analysis of Catalytic Sites of the Cell Wall Lytic N-Acetylmuramoyl-l-alanine Amidases CwlC and CwlV [PDF]
Journal of Biological Chemistry, 2001 The Bacillus subtilis CwlC and the Bacillus polymyxa var. colistinus CwlV are the cell wall lytic N-acetylmuramoyl-l-alanine amidases in the CwlB (LytC) family. Deletion in the CwlC amidase from the C terminus to residue 177 did not change the amidase activity. However, when the deletion was extended slightly toward the N terminus, the amidase activity
T, Shida +3 more
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