Results 11 to 20 of about 4,942 (222)

Improved antimicrobial spectrum of the N-acetylmuramoyl-L-alanine amidase from Latilactobacillus sakei upon LysM domain deletion [PDF]

World Journal of Microbiology and Biotechnology, 2021
Abstract The gene encoding N-acetylmuramoyl-L-alanine amidase in Latilactobacillus sakei isolated from a fermented meat product was cloned in two forms: its complete sequence (AmiC) and without one of its anchoring LysM domains (AmiLysM4). Deletion of the LysM domain is believed to affect the target microorganism’s affinity to the cell wall ...
Adriana López-Arvizu, Diana Rocha-Mendoza, Amelia Farrés, Edith Ponce-Alquicira, Israel García-Cano   +4 more
openaire   +5 more sources

Human Peptidoglycan Recognition Protein-L Is an N-Acetylmuramoyl-L-alanine Amidase [PDF]

Journal of Biological Chemistry, 2003
Peptidoglycan recognition proteins (PGRPs) are pattern recognition molecules coded by up to 13 genes in insects and 4 genes in mammals. In insects PGRPs activate antimicrobial pathways in the hemolymph and cells, or are peptidoglycan (PGN)-lytic amidases. In mammals one PGRP is an antibacterial neutrophil protein.
Zheng-Ming, Wang, Xinna, Li, Ross R, Cocklin, Minhui, Wang, Mu, Wang, Koichi, Fukase, Seiichi, Inamura, Shoichi, Kusumoto, Dipika, Gupta, Roman, Dziarski   +9 more
openaire   +4 more sources

Molecular Mimicry of NodA Genes by an N-acetylmuramoyl-L-alanine Amidases Gene in a Nodule Forming Staphylococcus cohnii [RESEARCH NOTE] [PDF]

The Philippine Agricultural Scientist, 2023
A rare, nodule-forming, Gram-positive bacterium (Sub4) was isolated from the forage and cover crop Pueraria phaseoloides, which aligned at 99.26% sequence identity to a partial 16S rDNA sequence of Staphylococcus cohnii sp. This was the first record of a
Aberathne, Aberathne Herath Mudiyanselage Nadeeshani Ruwandika, Gunawardana, Dilantha, Wedage, Wedage Methsala Madurangi   +2 more
core   +3 more sources

Genomic Analysis of 96 Paenibacillus larvae Bacteriophages Including 26 from Aotearoa, New Zealand [PDF]

Viruses
The bacterium Paenibacillus larvae is responsible for the devastating honey bee (Apis mellifera) disease American Foulbrood. Research into bacteriophages that infect P. larvae is growing rapidly due to increasing antibiotic resistance and restrictions on
Danielle N. Kok, Sophia P. Gosselin, Brenham Howard, Steven G. Cresawn, Philippos K. Tsourkas, Heather L. Hendrickson   +5 more
doaj   +2 more sources

Characterization of a novel cell wall hydrolase CwlE involved in Bacillus thuringiensis subsp. israelensis mother cell lysis

Frontiers in Microbiology, 2023
Cell wall hydrolases are ubiquitous among spore-form bacteria and essential for mother cell lysis. In this study, a novel cell wall hydrolase gene cwlE involved in mother cell lysis was characterized from Bacillus thuringiensis subsp.
Lixin Huang, Guangjie Han, Neil Crickmore, Chuanming Li, Yang Xia, Fuping Song, Jian Xu   +6 more
doaj   +2 more sources

Identification of a putative cell wall-hydrolyzing amidase involved in sporangiospore maturation in Actinoplanes missouriensis. [PDF]

J Bacteriol
Actinoplanes missouriensis is a filamentous bacterium that differentiates into terminal sporangia, each containing a few hundred spores. Previously, we reported that a cell wall-hydrolyzing N-acetylglucosaminidase, GsmA, is required for the maturation ...
Tan Z, Tezuka T, Ohnishi Y.
europepmc   +2 more sources

Autolytic system of Staphylococcus simulans 22: influence of cationic peptides on activity of N-acetylmuramoyl-L-alanine amidase [PDF]

Journal of Bacteriology, 1987
Pep 5 and nisin are cationic peptide antibiotics which in addition to their membrane-disruptive action induce autolysis in staphylococci. To investigate the mechanism of lysis induction, the influence of the peptides on the activity of the N-acetylmuramoyl-L-alanine amidase of Staphylococcus simulans 22 was studied.
G, Bierbaum, H G, Sahl
openaire   +4 more sources

Genomic and Transcriptomic Adaptation to Chlorhexidine in <i>Streptococcus</i> spp. [PDF]

J Dent Res
Antiseptics such as chlorhexidine digluconate (CHX) are widely used in clinical dental practice, but their potential risks, particularly regarding antimicrobial resistance (AMR), are not yet known.
Daller B, Auer DL, Buchalla W, Bartsch S, Gessner A, Jakubovics NS, Al-Ahmad A, Hiergeist A, Cieplik F.   +8 more
europepmc   +2 more sources

Screening of Novel Drug Targets and Drug Design for Bordetella pertussis: A Subtractive Proteomics Approach [PDF]

Current Research in Microbial Sciences
Bordetella pertussis causes whooping cough in humans that spreads directly from individual to individual mainly by aerosolized respiratory droplets. Nowadays, it gained the attention of scientific community because it has already been reemerged as one of
Md. Nazmul Islam Bappy, Foeaz Ahmed, Tahera Lasker, Emran Hossain Sajib, Md. Shariful Islam   +4 more
doaj   +2 more sources

Exploration of Human Skin Phageome to Reveal Endolysins and Novel Antimicrobial Peptides for Therapeutic Applications. [PDF]

Microbiologyopen
This study uncovers diverse endolysins and novel antimicrobial peptides from the human skin phageome, highlighting their potential to target antibiotic‐resistant pathogens and disrupt virulence mechanisms, paving the way for next‐generation skin therapeutics.
Paul JK, Akter A, Jewel NA, Rolin MH, Karim D, Niloy RK, Mondal SI.   +6 more
europepmc   +2 more sources