Results 51 to 60 of about 13,066,219 (329)
T cell senescence by N-glycan branching
Aging, 2022 Immune-senescence refers to the aging of the immune system and the resulting deterioration in its ability to fight infections and cancer in older individuals. This phenomenon is reflected in the numerous infectious diseases which show increased severity in the elderly, most recently demonstrated by the COVID-19 pandemic.
Mkhikian, Haik, Demetriou, Michael
openaire +4 more sources
Biological significance of complex N-glycans in plants and their impact on plant physiology
Frontiers in Plant Science, 2014 Asparagine (N)-linked protein glycosylation is a ubiquitous co- and post-translational modification which can alter the biological function of proteins and consequently affects the development, growth and physiology of organisms.
Richard eStrasser
doaj +1 more source
Improved method for drawing of a glycan map, and the first page of glycan atlas, which is a compilation of glycan maps for a whole organism. [PDF]
PLoS ONE, 2014 Glycan Atlas is a set of glycan maps over the whole body of an organism. The glycan map that includes data of glycan structure and quantity displays micro-heterogeneity of the glycans in a tissue, an organ, or cells. The two-dimensional glycan mapping is
Shunji Natsuka +3 more
doaj +1 more source
Molecular & Cellular Proteomics, 2015 Glycans present on glycoproteins and glycolipids of the major human parasite Schistosoma mansoni induce innate as well as adaptive immune responses in the host.
A. V. Diepen +5 more
semanticscholar +1 more source
Glycosylation in the thyroid gland : vital aspects of glycoprotein function in thyrocyte physiology and thyroid disorders [PDF]
, 2018 The key proteins responsible for hormone synthesis in the thyroid are glycosylated. Oligosaccharides strongly affect the function of glycosylated proteins.
Ewa Pocheć +2 more
core +1 more source
Scientific Reports, 2022 Serum N-glycan profiling studies during the past decades have shown robust associations between N-glycan changes and various biological conditions, including infections, in humans.
Laudine M. C. Petralia +10 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 2010 Human malignant malaria is caused by Plasmodium falciparum and accounts for almost 900,000 deaths per year, the majority of which are children and pregnant women in developing countries.
Cristiana S de Macedo +4 more
doaj +1 more source
Terminal Epitope-Dependent Branch Preference of Siglecs Toward N-Glycans
Frontiers in Molecular Biosciences, 2021 Siglecs are sialic acid–binding immunoglobulin-like lectins that play vital roles in immune cell signaling. Siglecs help the immune system distinguish between self and nonself through the recognition of glycan ligands.
Shuaishuai Wang +10 more
doaj +1 more source
Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking [PDF]
, 2009 We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells.
Altschuler Y. +8 more
core +3 more sources
N-Glycan Modification in Aspergillus Species [PDF]
Applied and Environmental Microbiology, 2008 ABSTRACT The production by filamentous fungi of therapeutic glycoproteins intended for use in mammals is held back by the inherent difference in protein N-glycosylation and by the inability of the fungal cell to modify proteins with mammalian glycosylation structures. Here, we report protein N-glycan engineering in two
Elke, Kainz +12 more
openaire +2 more sources