Results 51 to 60 of about 15,525,833 (178)

Sperm and Egg Jelly Coat from Sea Urchin Lytechinus variegatus Collected in Rio de Janeiro Contain Distinct Sialic Acid-Rich Polysaccharides

Brazilian Archives of Biology and Technology, 2015
This work found the occurrence of a distinct sialic acid-rich polysaccharide in the sperm surface of the sea urchin Lytechinus variegatus, which differed significantly from a similar molecule found in the egg jelly.
Gabrielle M. Valle, Leonardo P. Cinelli, Adriane R. Todeschini, Lycia de Brito-Gitirana, Ana-Cristina E.S. Vilela-Silva, Paulo A.S. Mourão   +5 more
doaj   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

ANALYSIS OF SIALIC ACIDS IN BOVINE INTESTINAL MUCINS [PDF]

, 1984
Molecular species of sialic acids released by mild acid hydrolysis from mucins of bovine small and large intestine were characterized by two dimensional thin layer chromatography and gas chromatography-mass spectrometry.
Masayo, NISHIURA
core   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

The Baboon as a Model to Study Human Health and Complex Disease

American Journal of Primatology, Volume 88, Issue 9, September 2026.
Baboons remain underappreciated as models of human biology and disease offering a distinct combination of biological and practical properties. In this review, we evaluate the baboon as a model for human complex diseases and make the case for broader use of baboons in translational research.
Brittany Hazzard, Yoav Gilad
wiley   +1 more source

DataSheet1_Aberrant N-glycolylneuraminic acid in breast MCF-7 cancer cells and cancer stem cells.docx

, 2022
N-Glycolylneuraminic acid (Neu5Gc) is not normally detected in humans because humans lack the hydroxylase enzyme that converts cytidine-5′-monophosphate-N-acetylneuraminic acid (CMP-Neu5Ac) to CMP-Neu5Gc; thus, any Neu5Gc appearing in the human body is ...
Zhixin Tian (1867531), Zhigang Cheng (647368), Qulian Guo (146481), Wenqian Yang (1947496), Yuan Jiang (296541)   +4 more
core   +1 more source

Xenotransplantation of the Porcine Lung—From Immunological Barriers to Emerging Experimental Strategies

Xenotransplantation, Volume 33, Issue 5, September/October 2026.
ABSTRACT Lung transplantation is the only long‐lasting life‐saving treatment for patients with end‐stage pulmonary disease, but the ever‐growing shortage of suitable donor organs leads to high mortality rates of the afflicted patients. Xenotransplantation, the transplantation of organs across species, has emerged as a promising alternative. This review
Nathalie Roters, Niveditha Varma, Robert Ramm, Heiner Niemann, Patrick Zardo, Arjang Ruhparwar, Tobias Goecke   +6 more
wiley   +1 more source

Mechanism of Uptake and Incorporation of the Non-human Sialic Acid N-Glycolylneuraminic Acid into Human Cells* [PDF]

Journal of Biological Chemistry, 2005
N-Glycolylneuraminic acid (Neu5Gc) is a widely expressed sialic acid in mammalian cells. Although humans are genetically deficient in producing Neu5Gc, small amounts are present in human cells in vivo. A dietary origin was suggested by human volunteer studies and by observing that free Neu5Gc is metabolically incorporated into cultured human carcinoma ...
Muriel, Bardor, Dzung H, Nguyen, Sandra, Diaz, Ajit, Varki   +3 more
openaire   +2 more sources

A Comprehensive Review of Our Current Understanding of Red Blood Cell (RBC) Glycoproteins

Membranes, 2017
Human red blood cells (RBC), which are the cells most commonly used in the study of biological membranes, have some glycoproteins in their cell membrane. These membrane proteins are band 3 and glycophorins A–D, and some substoichiometric glycoproteins (e.
Takahiko Aoki
doaj   +1 more source

Reduced Complement and Granulocyte Activation by α‐Gal Knockout Porcine Pericardium for Bioprosthetic Heart Valves: A Pilot Hemocompatibility Study

Journal of Biomedical Materials Research Part A, Volume 114, Issue 7, July 2026.
Genetically modified, α‐Gal‐depleted porcine pericardium and wild type tissues are investigated for hemocompatibility and material properties such as mechanobiology and ECM profile to carve out the suitability of the gene‐modified tissue as material for biological heart valve prostheses. ABSTRACT Xenogeneic pericardium is the main source for biological
Claudia Dittfeld, Elisabeth Kemter, Barbara Kessler, Eckhard Wolf, Anett Jannasch, Claudia Sperling, Sems‐Malte Tugtekin, Manfred F. Maitz   +7 more
wiley   +1 more source