Results 21 to 30 of about 3,818 (198)

Replication of H9 influenza viruses in the human ex vivo respiratory tract, and the influence of neuraminidase on virus release [PDF]

Scientific Reports, 2017
H9N2 viruses are the most widespread influenza viruses in poultry in Asia. We evaluated the infection and tropism of human and avian H9 influenza virus in the human respiratory tract using ex vivo respiratory organ culture.
Renee W. Y. Chan, Louisa L. Y. Chan, Chris K. P. Mok, Jimmy Lai, Kin P. Tao, Adebimpe Obadan, Michael C. W. Chan, Daniel R. Perez, J. S. Malik Peiris, John M. Nicholls   +9 more
doaj   +2 more sources

Polyclonal human antibodies against glycans bearing red meat-derived non-human sialic acid N-glycolylneuraminic acid are stable, reproducible, complex and vary between individuals: Total antibody levels are associated with colorectal cancer risk.

PLoS ONE, 2018
BackgroundN-glycolylneuraminic acid (Neu5Gc) is a non-human red-meat-derived sialic acid immunogenic to humans. Neu5Gc can be metabolically incorporated into glycan chains on human endothelial and epithelial surfaces. This represents the first example of
Annie N Samraj, Kimberly A Bertrand, Robert Luben, Zahra Khedri, Hai Yu, Dzung Nguyen, Christopher J Gregg, Sandra L Diaz, Sherilyn Sawyer, Xi Chen, Heather Eliassen, Vered Padler-Karavani, Kana Wu, Kay-Tee Khaw, Walter Willett, Ajit Varki   +15 more
doaj   +2 more sources

Possible Role of Dietary N-glycolyneuraminic Acid and Dysbiosis in Canine Enteropathy Pathogenesis [PDF]

N-glycolylneuraminic acid (Neu5Gc) is synthesized from its N-acetyl precursor (Neu5Ac) by cytidine-50- monophospho-N acetylneuraminic acid hydroxylase (CMAH). Absent in humans and ferrets, it is polymorphic in dogs.
Alessandra Gavazza, Barbara Simionati, Daniela Oliviero, Fiorella Carnevali, Giacomo Rossi, Ilaria Patuzzi, Livio Galosi, Lucia Biagini, Matteo Cerquetella, Sara Ricci, Sinem Gultekin   +10 more
core   +2 more sources

Analysis on the terahertz spectral characteristics of two types of sialic acids in solid state and aqueous solution [PDF]

Scientific Reports
In this study, N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) were chosen as representative sialic acids to study their terahertz (THz) spectral characteristics in solid and aqueous states.
Zhuang Peng, Yang Gao, Xinrui Zhang, Huiyu Yang, Bo Su, Kai Li, Cunlin Zhang   +6 more
doaj   +2 more sources

Screening and Characterization of Sialic Acid-Binding Variable Lymphocyte Receptors from Hagfish [PDF]

BioTech
Sialic acid is a diverse group of monosaccharides often found on the termini of N- and O-linked glycans as well as being components of glycoconjugates.
Mark Rickard N. Angelia, Abigail Joy D. Rodelas-Angelia, Cheolung Yang, Sojeong Park, Seung pyo Jeong, Hyeok Jang, Dennis Berbulla Bela-ong, Hobin Jang, Kim D. Thompson, Taesung Jung   +9 more
doaj   +2 more sources

Characterization of an Aptamer Targeting Neu5Gc, as an Endogenous Pathogenic Factor Derived from Red Meat [PDF]

Molecules
N-glycolylneuraminic acid (Neu5Gc), a sialic acid predominantly found in the non-neurohumoral fluids of hind-mouthed animals, is incapable of synthesizing Neu5Gc due to a deletion in the CMAH exon of the gene encoding human CMP-Neu5Gc hydroxylase.
Yuxi Guo, Honglin Ren, Han Wang, Yiran Xiao, Cong Wang, Mengdi Liu, Fuchun Duan, Haosong Li, Pan Hu, Yansong Li, Zengshan Liu, Shiying Lu   +11 more
doaj   +2 more sources

Detection of xenoglycan N-glycolylneuraminic acid (NEU5GC) On human sperm and directed anti-NEU5GC antibodies in seminal fluid

Fertility and Sterility, 2011
D. Wu, M. Thomas, R. Maxwell, S. Lindheim, P. Gagneux   +4 more
semanticscholar   +3 more sources

N-glycolylneuraminic acid (Neu5Gc) xenoglycan (XE) and directed antibodies (ABs) are present in the female reproductive tract

Fertility and Sterility, 2011
J. Sroga, I. Ressler, K. DiPaola, P. Gagneux, S. Lindheim   +4 more
semanticscholar   +2 more sources

The avian influenza A virus receptor SA-α2,3-Gal is expressed in the porcine nasal mucosa sustaining the pig as a mixing vessel for new influenza viruses [PDF]

Virus Research
Influenza A viruses (IAVs) originate from wild birds but have on several occasions jumped host barriers and are now also circulating in humans and mammals.
Charlotte Kristensen, Lars E. Larsen, Ramona Trebbien, Henrik E. Jensen   +3 more
doaj   +2 more sources

N-glycolylneuraminic acid as a carbohydrate cancer biomarker

Translational Oncology, 2023
One of the forms of aberrant glycosylation in human tumors is the expression of N-glycolylneuraminic acid (Neu5Gc). The only known enzyme to biosynthesize Neu5Gc in mammals, cytidine-5′-monophosphate-N-acetylneuraminic acid (CMAH), appears to be ...
Jing Wang, Lucy K. Shewell, Christopher J. Day, Michael P. Jennings   +3 more
doaj   +1 more source