Results 21 to 30 of about 54,300 (231)
, 2022 Accumulating evidence indicates that N6-methyladenosine (m6A) and long noncoding RNAs (lncRNAs) play crucial roles in cancer development. However, the biological roles of m6A and lncRNAs in lung cancer tumorigenesis are largely unknown.
Liang Zhu (172992) +3 more
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N6-methyladenosine (m6A) regulates signaling pathways during early embryo development
, 2022 N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA. In recent years, a slew of interesting studies had confirmed its essential role as a post-transcriptional regulator of gene expression in a wide range of biological ...
Jin, Kangxuan
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m6A-ELISA, a simple method for quantifying N6-methyladenosine from mRNA populations.
, 2023 N6-methyladenosine (m6A) is a widely studied and abundant RNA modification. The m6A mark regulates the fate of RNAs in various ways, which in turn, drives changes in cell physiology, development, and disease pathology.
Imke Ensinck (14263964) +6 more
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Molecular Therapy: Nucleic Acids, 2020 N6-Methyladenosine (m6A) is the most common internal modification of eukaryotic messenger RNA (mRNA) that occurred on the N6 nitrogen of adenosine. However, the roles of m6A in oral squamous cell carcinoma (OSCC) are still elusive.
Wei Zhao +9 more
doaj +1 more source
Isothermal Amplification-Based Detection of Single-Base RNA N6-Methyladenosine
, 2023 N6-methyladenosine (m6A) has recently gained much attention due to its diverse biological functions. Currently, the commonly used detection methods for locus-specific m6A marks are complicated to operate, it is difficult to quantify the methylation level,
Cheng Yi (4502179) +11 more
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Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing
Nature Communications, 2023 Direct RNA sequencing using nanopore platform can be used to detect N6-methyladenosine (m6A) modifications on mRNAs. Here the authors systematically compare tools used for m6A detection from nanopore direct sequencing.
Zhen-Dong Zhong +11 more
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Frontiers in Genetics, 2022 Background: N6-methyladenosine (m6A) is the most extensive messenger RNA modification. Despite recent advances in the biological roles of m6A, its role in the development and progression of renal cell carcinoma (RCC) remains unclear.Methods: In this ...
Ying Gan +17 more
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N6-Methyladenosine modification: a novel pharmacological target for anti-cancer drug development
Acta Pharmaceutica Sinica B, 2018 N6-Methyladenosine (m6A) modification is the most pervasive modification of human mRNA molecules. It is reversible via regulation of m6A modification methyltransferase, demethylase and proteins that preferentially recognize m6A modification as “writers”,
Yi Niu +4 more
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A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
Nature Communications, 2021 Epitranscriptomic modifications can regulate learning and memory. Here, the authors provide proteomic and functional analysis of N6-methyladenosine (m6A)-binding proteins in D.
Lijuan Kan +7 more
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, 2021 As one of the most common forms of RNA modification, N6-methyladenosine (m6A) RNA modification has attracted increasing research interest in recent years.
Lihong Yin (328532) +9 more
core +1 more source